Antibacterial Activity of Gel of Ethanol Extract of Papaya Leaves (Carica papaya L.) againts Propionobacterium acnes

Abstract

Abstract
 Papaya plants (Carica papaya L) besides being a food ingredient are also believed to have medicinal properties and are used traditionally, one of which is in dealing with acne problems. The purpose of this study was to formulate papaya leaf extract in the form of a gel preparation and test its antibacterial activity against the Propionibacterium acnes bacteria. The preparation of the ethanol extract of papaya leaves was made in three concentrations namely 5, 10 and 15%, then tested for antibacterial activity and compared with negative controls (blank gel) and positive control (erythromycin). The results showed that the papaya extract ethanol extract of 10 and 15% leaves had significantly different activities to the negative controls, but the 5% gel formula did not show any different activity towards negative controls. The conclusion of this study is that active papaya leaf ethanol extract gel inhibits bacterial growth at concentrations of 10 and 15%.
 Keywords: Carica papaya L., gel formula, antibaterial activity, Propionibacterium acnes

Antibacterial Activities of Belimbing Wuluh (Averrhoa Bilimbi L.) Ethyl Acetate Extract on Gel Formulated Against Propionibacterium Acnes and Staphylococcus Aureus

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“…The number shown by the pH meter is the pH of the preparation. The pH of gel must be in accordance with the skin pH, specifically 4.5-6.5 [12,13].…”

“…The addition of the load is continued until a constant diameter is obtained. The spreadability of 5-7 cm indicates a semisolid consistency, which is very comfortable in use [12,13].…”

Chemical Composition, Antioxidant Potential, and Antimicrobial Activity of Elettaria cardamomum Essential Oil

“…Eventually, more bacteria were added to the bacterial suspension. The turbidity of 0.5 McFarland standard was equal to 1.5×10 8 CFU/mL of bacteria, in order to reach a turbidity of 10 6 CFU/mL, this solution was diluted twice (16) . Preparation of extract: A 50000 ppm stock solution was prepared from cardamom essential oil; of which 0.35 g was weighed and added to 7 mL of dimethyl sulfoxide (DMSO) solvent and 7 mL of ethanol solvent each.…”

In Vitro Test of Anticalculi Effect from Ethyl Acetate Fraction of Chives Leaf (Allium schoenoprasum L.)

“…40 g of chives leaf ethanol extract was fractioned using ethyl acetate solvent, homogenized and partitioned by using separatory funnel. Then the ethyl acetate fraction were concentrated with a rotary evaporator at 50 o C [8].…”