Anti-oxidant, antimicrobial and anti-acetylcholinesterase activities of organic extracts from aerial parts of three Tunisian plants and correlation with polyphenols and flavonoids contents

Abstract

<p class="Abstract">In goal of searching new active compounds with important biological activities, a screening of several plants from salt-marsh region of Chebba-Tunisia had been realized. Three species had been selected: <em>Calendula arvensis, Chenopodium murale</em> and <em>Nicotiana glauca</em>. The organic extracts of different aerial parts of these plants (stems, leaves and flowers) displayed variable contents of total polyphenols (TPP) and total flavonoids (TF). Flowers acetone extract from <em>N. glauca</em> contained the higher quantity in TPP (264.8 ± 1.6 µg GA/mg), while stems dichloromethane extract exhibited the best TF content (49.8 ± 2.2 µg QE/mg). The important TPP and TF contents reflected a good anti-oxidant and antimicrobial activities. The best acetylcholinesterase inhibitory activity had been shown in the fractions obtained after extraction with low polarity solvents. Whence, a correlation of flavonoids contents with biological activities had been shown, while, there was no correlation with acetylcholinesterase inhibitory activity.</p><p> </p>

Bioactive secondary metabolites from new endophytic fungus Curvularia. sp isolated from Rauwolfia macrophylla

“…The antimicrobial activity of the isolated compounds was studied using micro-dilution method with some modification [18]. The bacterial strains, Escherichia coli (DSMZ1058), Micrococcus luteus (DSMZ1605), Pseudomonas agarici (DSMZ11810), and Staphylococcus warneri (DSMZ20036) were grown on a nutrient agar medium (3 g L −1 beef extract, 10 g L −1 peptone, and 20 g L −1 agar) and the pH was adjusted to 7.2.…”

GC-MS Based Metabolite Profiling, Antioxidant and Antimicrobial Properties of Different Solvent Extracts of Malaysian Plectranthus amboinicus Leaves

“…Recent studies have suggested the success of this herb against oral, respiratory, skin, cardiovascular, digestive, and urinary diseases [2]. Previous studies have witnessed the existence of significant variations in secondary metabolites accumulation among the same plant species grown under diverse ecological conditions [5, 6]. In general, various solvents are used for extracting plant metabolites from their different parts.…”

Anti-oxidant, anti-inflammatory and enzyme inhibitory activities of 10 selected Unani herbs

“…These studies mainly focus on the individual plant. Comparative studies are a few (Alam et al, 2014;Sellem et al, 2016). In the present letter, the antimicrobial, antioxidant, anti-inflammatory, and enzyme inhibitory activity as well as phytochemical analysis of 10 selected herbs (Rubia cordifolia, Rauwolfia serpentine, Origanum vulgare, Hyssopus officinalis, Cichorium intybus, Malva sylvestris, Portulaca oleracea, Aristolochia indica, Achyranthes aspera, Symplocos racemosa) are shown and compared.…”