Background: In the current study, different plant extracts of Gynocardia odorata such as methanol extract (ME), aqueous soluble fraction (AQSF), chloroform soluble fraction (CSF), carbon tetrachloride soluble fraction (CTCSF), and petroleum ether soluble fraction (PESF) were examined for the analysis of thrombolytic, cytotoxic, and erythrocyte membrane-stabilizing activities.