Anti–inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees

Saleem, TK Mohamed; Azeem, A. K.; Dilip, C; Sankar, Cheriyedath Raj; ., N.V. Prasanth; Duraisami, Rasilingam

doi:10.1016/s2221-1691(11)60014-2

Cited by 104 publications

(51 citation statements)

References 7 publications

(6 reference statements)

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“…hydrolytic enzymes) which are associated to inflammatory process. 21 The result (Table 2) suggest that the plant extracts could have anti-inflammatory potential via membrane stabilization mechanism. Data are presented as mean ± SEM (n = 3).…”

Section: Resultsmentioning

confidence: 99%

Preliminary Phytochemical and Pharmacological Screenings of Plumbago indica L. and Alpinia conchigera Griff.

Ibrahim

Hossain

Shajib

et al. 2018

Dhaka Univ. J. Pharm. Sci

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Section: Resultsmentioning

confidence: 99%

Preliminary Phytochemical and Pharmacological Screenings of Plumbago indica L. and Alpinia conchigera Griff.

Ibrahim

Hossain

Shajib

et al. 2018

Dhaka Univ. J. Pharm. Sci

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“…Different types of plants possess antiinflammatory activities. This study involved hypotonic solution-and heat-induced hemolysis in mice models on the basis of their membrane-stabilizing properties (Saleem et al 2011;Umukoro et al 2006).…”

Section: Resultsmentioning

confidence: 99%

Canvassing of thrombolytic, cytotoxic, and erythrocyte membrane-stabilizing attributes in in vitro screening of Gynocardia odorata

et al. 2014

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“…The following procedure was followed by for evaluating the percentage of inhibition of protein denaturation 22 .…”

Section: Inhibition Of Albumin Denaturationmentioning

confidence: 99%

In Vitro Anti-Inflammatory and Anti-Diabetic Activity of Methanolic Extract of Cardanthera Difformis Druce

De¹,

Das²,

Mandal³

2017

Int. Res. J. Pharm.

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In rural and backward areas of West Bengal in India, several plants were commonly used as herbal medicine for the treatment of many diseases without studying any photochemical and biological information in detail. The current study was to investigate the anti-inflammatory and antidiabetic study of methanolic extract of Cardanthera difformis. Methanolic extract of Candanthera difformis was screened for anti-inflammatory activity by denaturation of egg albumin. The methanolic extract of Candanthera difformis was subjected to in vitro inhibition of protein denaturation in various concentrations i.e. 100, 200, 400, 800, 1000 µg/ml. Methanolic extract exhibited a concentration dependent inhibition of protein (albumin) denaturation. The anti-diabetic behaviour of methanol extracts of whole plant of Cardanthera difformis using the standard optical density assay were investigated against the two very essential enzyme α-amylase and α-glucosidase. The intestinal digestive enzymes play a vital role in the carbohydrate digestion. Pancreatic alpha-amylase and glucosidase inhibitors offer an effective strategy to lower the levels of post prandial hyperglycaemia via control of starch breakdown. The goal of the present study is to improve in vitro evidence of potential inhibition of alpha-amylase and alpha-glucosidase enzymes by using the methanolic extract of Cardanthera difformis. The present study suggests that the crude extract of Cardanthera difformis effectively act as in vitro anti-inflammatory and in vitro anti-diabetic activity.

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Anti–inflammatory activity of the leaf extacts of Gendarussa vulgaris Nees

Abstract: The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.

Cited by 104 publications

References 7 publications

Preliminary Phytochemical and Pharmacological Screenings of Plumbago indica L. and Alpinia conchigera Griff.

Preliminary Phytochemical and Pharmacological Screenings of Plumbago indica L. and Alpinia conchigera Griff.

Canvassing of thrombolytic, cytotoxic, and erythrocyte membrane-stabilizing attributes in in vitro screening of Gynocardia odorata

In Vitro Anti-Inflammatory and Anti-Diabetic Activity of Methanolic Extract of Cardanthera Difformis Druce

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