Anti-Diabetic Effects of Some Medicinal Plants in Experimental Animals: A Review

Maqbool, Mudasir; Gani, Imran; Dar, Mohmad Amin

doi:10.22270/ajprd.v7i1.469

Cited by 19 publications

(6 citation statements)

References 17 publications

(17 reference statements)

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“…Results indicated that AMAE attenuated body weight gain as compared HFD control group were in agreement with who found that AM extracts attenuated body weight gain and exhibited anti-obesity activity may due to decrease fat pad mass, by reduced adipocyte differentiation or by decreasing adipocyte hypertrophy in high fat diet induced obese rats. Also, Maqbool et al, (2019) and Siddiqui et al, (2019) reported that Aegle marmelos is effective in restoration the body weight to normal levels.…”

Section: Resultsmentioning

confidence: 96%

bioactive role of aqueous extract of aegle marmelos leaves on obese rats

Sharshar

Ameen

El-Masry

2022

ijhs

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The aim of this study was to evaluate the effect of Aegle marmelos aqueous extract (AMAE) leaves on obese rats. Twenty-five adult male albino rats (Sprague-Dawley strain), weighing about (200±10g) were divided randomly into two main groups as follow: the first group (-Ve control= 5 rats) was fed on basal diet. The second group (20 rats) was fed on high fat diet (HFD) for 4 weeks then divided equally to 4 groups from group 2 to group 5. Group 2 (+Ve control) fed on basal diet. Group 3, 4 and 5 fed on HDF administrated orally with 1, 2 and 3 ml of AMAE, respectively. At the end of the experimental period (4 weeks), rats were scarified and serum was collected to determine levels of lipid profile, glucose, leptin kidneys and liver functions. The results showed that the body weight of rats and serum levels of lipids profile, leptin, glucose, kidneys functions and liver enzymes were elevated by HFD administration (positive control group) compared with negative control group, while HDL-C decreased. It was also found that oral administration of AMAE diet with reversed these changes that caused by HFD.

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Section: Resultsmentioning

confidence: 96%

bioactive role of aqueous extract of aegle marmelos leaves on obese rats

Sharshar

Ameen

El-Masry

2022

ijhs

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“…According to new study, the leaf juice from A.Marmelos was effective in diabetes mellitus, which may be attributed to the presence of bioactive components such as aegelin, scopoletin, and sitosterol in the leaves. 14,15…”

Section: Antihyperglycemic Activitymentioning

confidence: 99%

A review on phytochemical and pharmacological values of Aegle marmelos

Lomate¹,

Murthy²,

Adak³

et al. 2021

J. Drug Delivery Ther.

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India is the largest producer of medicinal plants and is rightly referred to as "the World's Botanical Garden." Medicinal plants play a key role in the health and vitality of humans and animals alike. Researchers have been attempting to recognize and validate plant-derived substances for the treatment of various diseases that promote compounds for health and nutrition for the past few years. Bael is a common plant that originated in India (Aegle marmelos). According to a study of the literature, entire parts of the plant, such as roots, barks, leaves, fruits, seeds, and flowers, are used to treat various diseases. Bangladesh, Indonesia, China, and other Asian countries, for example, it is a spiritual, religious, and medicinal plant that can be found all over the world. It has a number of therapeutic applications. Nowadays, various products from various parts of the plant are prepared. The biological profile, botanical description, physicochemical parameters, conventional uses, therapeutic applications and creative aspects are included in this study. The purpose of the present analysis is to compile the general chemical profile, both medicinal and economic value, value-added items such as juice, jam and toffee, and other uses of Aegle marmelos. Keywords: Aegle marmelos, Rutaceae, Medicinal Values

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“…[87] The hexane fraction of N. sativa seeds' methanol extract revealed substantial anti-inflammatory activity by inhibiting nitric oxide release in lipopolysaccharide-stimulated RAW 264.7 macrophages, with an IC50 value of 6.20 μg/mL (Pichette et al, 2012). [88][89][90] A clinical trial study was conducted as prospective and double blind with descriptive analytic to investigate the antiinflammatory property of N. sativa in patients with symptoms of allergic rhinitis. 66 patients (placebo and case) with allergic rhinitis were involved and exposed to N. sativa oil.…”

Section: Hepatoprotective Actionmentioning

confidence: 99%

Pharmaceutical Significance of Nigella Sativa L., a Wonder Herb

Ara

Maqbool

Fekadu

et al. 2021

J App Pharm Sci Res

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Nigella sativa L. (Family: Ranunculaceae; commonly known as black cumin) is an annual herb. N. sativa is cultivated and distributed all over India, especially in Punjab, Himachal Pradesh, Gangetic plains, Bihar, Bengal, Assam and Maharashtra. Among the traditional remedies, prescriptions of Nigella sativa for the treatment of various diseases are well-known since the prehistoric era. Therapeutic effects of Nigella sativa are thought to be due to nigellone and thymoquinone contents. The reported pharmacological properties include protection against disease and chemical-induced renal and hepatic toxicity, anti-inflammatory, analgesic, antipyretic, anti-microbial and antineoplastic activities. The oil decreases blood pressure, cholesterol, triglycerides, and glucose and increases respiration, hemoglobin and packed cell volume. In the traditional system of medicine, black cumin seeds are effective against cough, bronchitis, asthma, chronic headache, migraine, dizziness, chest congestion, dysmenorrheal, obesity, diabetes, paralysis, hemiplegia, back pain, infection, inflammation, rheumatism, hypertension and gastrointestinal problems such as dyspepsia, flatulence, dysentery, and diarrhea. In this review, we will elaborate about this wonder herb having miraculous effects.

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Anti-Diabetic Effects of Some Medicinal Plants in Experimental Animals: A Review

Cited by 19 publications

References 17 publications

bioactive role of aqueous extract of aegle marmelos leaves on obese rats

bioactive role of aqueous extract of aegle marmelos leaves on obese rats

A review on phytochemical and pharmacological values of Aegle marmelos

Pharmaceutical Significance of Nigella Sativa L., a Wonder Herb

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