Angiotensin II reverses the inhibitory action produced by theca cells on bovine oocyte nuclear maturation

Giometti, Inês Cristina; Bertagnolli, Angélica Cavalheiro; Ornes, Roberta Caroline; Costa, Luis Fabiano Santos Da; Carambula, Silvia; Reis, Adelina Martha dos; Oliveira, João Francisco Coelho de; Emanuelli, Isabele Picada; Gonçalves, Paulo Bayard Dias

doi:10.1016/j.theriogenology.2004.05.022

Cited by 32 publications

(39 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The high rate of embryo development demonstrates that saralasin did not change the kinetics of oocyte nuclear and cytoplasmatic maturation. These results show that saralasin does not have a direct effect on bovine oocyte, which are in agreement with those reported previously (Giometti et al 2005, Stefanello et al 2006.…”

Section: Discussionsupporting

confidence: 94%

“…Resumption of meiosis in fully grown follicles is triggered by a preovulatory surge of LH (Ayalon et al 1972, Dekel et al 1979, and herein we report the inhibition of these events by a competitive AngII antagonist. These results are complementary to previous findings of our group regarding oocyte meiotic resumption (Giometti et al 2005, Stefanello et al 2006) and ovulation, an event closely related to oocyte maturation (Ferreira et al 2007). Together, these results suggest that AngII is an important intrafollicular mediator of the LH surge to induce meiotic resumption in bovine oocytes.…”

Section: Discussionsupporting

confidence: 87%

“…The dissection and follicle culture procedures have been previously conducted in our laboratory and validated by measuring the progesterone and estradiol ratio and by histological analysis (Giometti et al 2005, Stefanello et al 2006.…”

Section: Angiotensin II In Bovine Oocyte Meiosis Resumptionmentioning

confidence: 99%

“…AngII has also been associated with follicular growth (Ferreira et al 2008) and ovulation in cows (Acosta et al 2000, Ferreira et al 2007. Furthermore, AngII stimulated the resumption of meiosis in co-culture systems of cumulusenclosed bovine oocytes and follicular cells (Giometti et al 2005, Stefanello et al 2006. AngII is the active octapeptide hormone product of the renin enzymatic cascade, and two receptor subtypes of AngII have been identified (Bottari et al 1993, De Gasparo et al 1995, Gallinat et al 2000.…”

Section: Introductionmentioning

confidence: 99%

“…In spite of reports that AngII induces meiotic resumption in oocytes co-cultured with follicular cells (Giometti et al 2005, Stefanello et al 2006, there is no information available regarding the requirement of AngII for oocyte resumption of meiosis after the LH surge. Consequently, our hypotheses were that AngII is essential for meiotic resumption after the LH surge and that it acts through PTGS2-mediated PG synthesis.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Evidence that the effect of angiotensin II on bovine oocyte nuclear maturation is mediated by prostaglandins E2 and F2α

Barreta

Oliveira²,

Ferreira³

et al. 2008

Reproduction

View full text Add to dashboard Cite

Angiotensin II (AngII) prevents the inhibitory effect of follicular cells on oocyte maturation, but its involvement in LH-induced meiotic resumption remains unknown. The aim of this study was to assess the involvement of AngII in LH-induced meiotic resumption and of prostaglandins (PGs) in the action of AngII. In the experiment I, seven cows were superovulated, intrafollicularly injected with 10 mM saralasin (a competitive AngII antagonist) or saline when the follicles reached a diameter larger than 12 mm, and challenged with a GnRH agonist to induce an LH surge. Fifteen hours after GnRH, the animals were ovariectomized and the oocytes were recovered to determine the stage of meiosis. The oocytes from follicles that received saline were in germinal vesicle (GV) breakdown (30.8%) or metaphase I (MI; 69.2%) stage while those that received saralasin were in the GV stage (100%; P!0.001) 15 h after GnRH agonist. In another experiment, oocytes were co-cultured with follicular hemisections for 15 h to determine whether PGs mediate the effect of AngII on meiotic resumption. Indomethacin (10 mM) inhibited AngII-induced meiotic resumption (13.4 vs 77.5% MI without indomethacin; P!0.001). Furthermore, the GV oocytes progressed to MI at a similar rate when PGE 2 , PGF 2a or AngII was present in the co-culture system with follicular cells (PGE 2 77.4%, PGF 2a 70.0%, and AngII 75.0% MI). In conclusion, our results provide strong evidence that AngII mediates the resumption of meiosis induced by an LH surge in bovine oocytes and that this event is dependent on PGE 2 or PGF 2a produced by follicular cells. Reproduction (2008) 136 733-740

show abstract

Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 87%

Section: Angiotensin II In Bovine Oocyte Meiosis Resumptionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Evidence that the effect of angiotensin II on bovine oocyte nuclear maturation is mediated by prostaglandins E2 and F2α

Barreta

Oliveira²,

Ferreira³

et al. 2008

Reproduction

View full text Add to dashboard Cite

show abstract

Induction of multiple ovulation via modulation of angiotensin II receptors in in vitro ovarian follicle culture models

Kim

Kang

et al. 2016

J Tissue Eng Regen Med

View full text Add to dashboard Cite

In vitro culture of ovarian follicles is a promising bioengineering technique for retrieving fertilizable oocytes from preserved ovarian tissues of cancer survivors. However, current in vitro follicle culture techniques are labour-intensive and of low efficiency, as only single follicle culture (SFC) has been possible to date. The present study investigated the feasibility of multifollicular cluster culture (MFCC) system using angiotensin II receptor (ATII-Rc) analogues. Ovarian pre-antral follicles isolated from 2-week-old C57BL6 mice were cultured with ATII-Rc agonist or antagonist and their maturation outcomes were compared with control group. When single follicles were cultured, the ovulation and maturation rates were similar in all three groups. When three-follicle clusters were cultured, up to three follicles were ovulated in the ATII-Rc agonist group while none or one follicle ovulated in control or antagonist groups (p < 0.0001). Significantly higher numbers of mature oocytes were obtained in the agonist group (three-follicle 28.2 ± 4.9 vs. SFC 11.0 ± 1.3, per 25 cultured droplets) (p < 0.0001), and the development of each fertilized oocytes was comparable to those from SFC. It is therefore concluded that this novel MFCC system can significantly improve the efficiency of in vitro mature oocyte retrieval via ATII-Rc modulation. Copyright © 2016 John Wiley & Sons, Ltd.

show abstract

Plausible Impacts of SARS-CoV-2 on Human Reproductive System

Sharma

Kumari

2021

Delineating Health and Health System: Mechanistic Insights Into Covid 19 Complications

View full text Add to dashboard Cite

Angiotensin II reverses the inhibitory action produced by theca cells on bovine oocyte nuclear maturation

Cited by 32 publications

References 36 publications

Evidence that the effect of angiotensin II on bovine oocyte nuclear maturation is mediated by prostaglandins E2 and F2α

Evidence that the effect of angiotensin II on bovine oocyte nuclear maturation is mediated by prostaglandins E2 and F2α

Induction of multiple ovulation via modulation of angiotensin II receptors in in vitro ovarian follicle culture models

Plausible Impacts of SARS-CoV-2 on Human Reproductive System

Contact Info

Product

Resources

About