“…The high sensitivity of laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) makes it the preferred technique for imaging trace elements in biological tissues. Since the seminal paper of Gray, there has been significant improvements in the speed, sensitivity, and resolution of LA-ICP-MS imaging with growing utility for medical, life science, environmental, geoscience, and food safety applications. − However, there has been sporadic development of data reduction software with no preferred open-source option available. While a large library of software does exist for the conversion and analysis of MS imaging (MSI) data, very few of these programs focus on LA-ICP-MS data specifically (Table ).…”