Metallomics in Multidisciplinary Research and the Analytical Advances

Li, Yufeng

doi:10.46770/as.2021.108

Cited by 8 publications

(4 citation statements)

References 36 publications

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“…The extensive development of the metallomic approaches in different scientific fields and research subjects has resulted in the accumulation of a vast volume of experimental data. Due to the need to systematize the available literature accumulating on the matter in different directions, a problem arises from the division of the separated subgroups in metallomic studies [ 47 ]. Metallomics could be divided into subgroups in several ways, depending on the criteria for classification, with the focus on various aspects of the problem.…”

Section: Metallomics As a Scientific Approachmentioning

confidence: 99%

Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

Fedenko

Landi

Shemet³

2022

IJMS

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Plant adaptive strategies have been shaped during evolutionary development in the constant interaction with a plethora of environmental factors, including the presence of metals/metalloids in the environment. Among adaptive reactions against either the excess of trace elements or toxic doses of non-essential elements, their complexation with molecular endogenous ligands, including phenolics, has received increasing attention. Currently, the complexation of phenolics with metal(loid)s is a topic of intensive studies in different scientific fields. In spite of the numerous studies on their chelating capacity, the systemic analysis of phenolics as plant ligands has not been performed yet. Such a systematizing can be performed based on the modern approach of metallomics as an integral biometal science, which in turn has been differentiated into subgroups according to the nature of the bioligands. In this regard, the present review summarizes phenolics–metal(loid)s’ interactions using the metallomic approach. Experimental results on the chelating activity of representative compounds from different phenolic subgroups in vitro and in vivo are systematized. General properties of phenolic ligands and specific properties of anthocyanins are revealed. The novel concept of metallophenolomics is proposed, as a ligand-oriented subgroup of metallomics, which is an integrated approach to study phenolics–metal(loid)s’ complexations. The research subjects of metallophenolomics are outlined according to the methodology of metallomic studies, including mission-oriented biometal sciences (environmental sciences, food sciences and nutrition, medicine, cosmetology, coloration technologies, chemical sciences, material sciences, solar cell sciences). Metallophenolomics opens new prospects to unite multidisciplinary investigations of phenolic–metal(loid) interactions.

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Section: Metallomics As a Scientific Approachmentioning

confidence: 99%

Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

Fedenko

Landi

Shemet³

2022

IJMS

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“…As an emerging interdisciplinary science, metallomics aims to integrate the research fields related to metals and metalloids in biological systems from a systematic perspective. 3,7 In this context, metallomics is extremely complicated. On the other hand, the metallome is highly dynamic because many metal complexes and intermediates are thermodynamically unstable and easily change.…”

Section: Metallomics: Concept and Historymentioning

confidence: 99%

ICP-MS-Based Methodology In Metallomics: Towards Single Particle Analysis, Single Cell Analysis, And Spatial Metallomics

Chen¹,

Wang²

2022

At.Spectrosc.

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As an emerging interdisciplinary science, metallomics aims to integrate research fields related to metals and metalloids in biological systems from a systematic perspective. Inductively coupled plasma mass spectrometry (ICP-MS) is considered one of the most versatile tools for metallomics research. This review presents a brief overview of ICP-MS and describes recent advances in ICP-MS instrumentation. Then, ICP-MS-based methods and applications are discussed, focusing on single particle analysis, single cell analysis, and spatial metallomics. With the rapid developments in instrumentation and methodology, ICP-MS-based methodologies will evolve further and play a dominant role in metallomics research.

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“…Metal ions play a crucial role in various important biochemical functions within the human body, [1][2][3] making it essential to monitor their concentrations, particularly in homeostatic environments such as serum. 4 For instance, patients with bipolar disorder (BD) typically rely on long-term lithium (Li) drug therapy, necessitating continuous monitoring of serum Li concentrations to maintain an effective concentration range and prevent side effects caused by excess concentrations.…”

Section: Introductionmentioning

confidence: 99%

Development of a droplet cathode glow discharge excitation source for high throughput detection of Li, Ca and K in serum samples

Liu,

Dong,

Han

et al. 2024

J. Anal. At. Spectrom.

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Metallomics in Multidisciplinary Research and the Analytical Advances

Cited by 8 publications

References 36 publications

Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

ICP-MS-Based Methodology In Metallomics: Towards Single Particle Analysis, Single Cell Analysis, And Spatial Metallomics

Development of a droplet cathode glow discharge excitation source for high throughput detection of Li, Ca and K in serum samples

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