2014
DOI: 10.1590/0037-8682-0128-2014
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Analysis of the prevalence of dyslipidemia in individuals with HIV and its association with antiretroviral therapy

Abstract: Introduction: Antiretroviral therapy (ART) has been used to treat large numbers of patients living with human immunodefi ciency virus (HIV) infection. Lipid disorders are often observed in these patients, and include elevations in total cholesterol (TC) and triglycerides (TG). Methods: A cross-sectional study was performed using 333 patient records from the Regional Hospital of São José Doutor Homero de Miranda Gomes (HRSJHMG). The study population consisted of patients with HIV who were under medical follow u… Show more

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Cited by 12 publications
(13 citation statements)
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“…Many studies also reported a similar finding. 33,34 This positive association could be explained by the possible interaction of aging, HIV infectious process and the drug adverse outcome on lipid metabolism. 23 Moreover, the study also showed that lower odds of dyslipidemia were found among subjects who have attained a lower level of education (no formal education, primary and secondary education) compared to those who attained college and above.…”
Section: Discussionmentioning
confidence: 99%
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“…Many studies also reported a similar finding. 33,34 This positive association could be explained by the possible interaction of aging, HIV infectious process and the drug adverse outcome on lipid metabolism. 23 Moreover, the study also showed that lower odds of dyslipidemia were found among subjects who have attained a lower level of education (no formal education, primary and secondary education) compared to those who attained college and above.…”
Section: Discussionmentioning
confidence: 99%
“…28 The discrepancy is more likely due to gender-related exercise habits and biologic differences in males and females in handling ART adverse outcomes. 20 In addition, the consequence of the increased life expectancy of PLHIV results from the growing number of women living with HIV going through the physical as well as hormonal changes of the menopausal transition. Despite the viral suppression and immune recovery promoted by modern treatment, aging, together with prolonged exposure to antiretroviral drugs, may increase the risk of dyslipidemia in women.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…En effet, l'infection au VIH est fortement associée à des anomalies du métabolisme lipidique, notamment une hypercholestérolémie, une élévation des taux du VLDL et des triglycérides et une diminution du taux de cholestérol HDL. On assiste ainsi à une mauvaise répartition corporelle de la graisse et à l'insulinorésistance [ 4 ]. Ces différentes anomalies favorisent le syndrome métabolique.…”
Section: Introductionunclassified
“…The results of the study were in correlation with studies conducted by Calza et al in 2009, [6] PNS et al in 2013, [7] V I et al in 2014, [8] , Bekolo et al in 2014, [9] Limas et al in 2014. [10] Previous reports have demonstrated that HIVinfected patients exhibit multiple abnormalities in lipid metabolism parameters both in pre-HAART and post-HAART eras, especially with the use of protease inhibitors (PIs). Several mechanisms have been proposed to explain the dyslipidemia seen with both HIV infection and exposure to ART.…”
Section: Resultsmentioning
confidence: 99%