2020
DOI: 10.1016/j.neuroscience.2020.09.009
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Analysis of the Circular Transcriptome in the Synaptosomes of Aged Mice

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Cited by 8 publications
(4 citation statements)
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“…Another example is circ‐Mbl which is principally expressed in the Drosophila 's head than its ovaries (Westholm et al, 2014). On the other hand, developmental stage‐ or age‐related abundance of circRNAs, as the other characteristic, is defined as the alteration of circRNAs' expression level with the process of aging (Curry‐Hyde et al, 2020; Gruner et al, 2016; Meng et al, 2017).…”
Section: An Outlook On Circrnasmentioning
confidence: 99%
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“…Another example is circ‐Mbl which is principally expressed in the Drosophila 's head than its ovaries (Westholm et al, 2014). On the other hand, developmental stage‐ or age‐related abundance of circRNAs, as the other characteristic, is defined as the alteration of circRNAs' expression level with the process of aging (Curry‐Hyde et al, 2020; Gruner et al, 2016; Meng et al, 2017).…”
Section: An Outlook On Circrnasmentioning
confidence: 99%
“…During the biogenesis of exonic circRNA (ecircRNA), direct backsplicing is preferred to be occurred instead of the exon skipping (Jeck & Sharpless, 2014). According to their composition, circRNAs can be categorized into four subclasses: (i) ecircRNAs; (Curry‐Hyde et al, 2020) circular intronic RNAs (ciRNAs); (iii) exon–intron circRNAs (EIciRNAs); and (iv) tRNA intronic circular RNAs (tricRNAs) (Geng et al, 2020). EcircRNAs, which are mostly distributed in the cytoplasm, have been reported as the most identified circRNAs (~80% of all subtypes) (Jeck et al, 2013; Memczak et al, 2013).…”
Section: An Outlook On Circrnasmentioning
confidence: 99%
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“…The hippocampus has been shown to express specific regions of circRNAs in the mouse brain (Rybak-Wolf et al, 2015). Some studies have shown that circRNAs are specifically located in dendrite (You et al, 2015), axons (Qian et al, 2022) and synapses (Curry-Hyde et al, 2020), regulating synaptic plasticity (Xu et al, 2020). CircRNAs also play a causative role in aging and longevity, whose levels are also altered in an age-dependent manner across specific human organs and tissues (Kim et al, 2021).…”
Section: Introductionmentioning
confidence: 99%