Analysis of haloacetic acids in water by a novel technique: simultaneous extraction– derivatization

Benanou, D.; Acobas, F.; Sztajnbok, Pascale

doi:10.1016/s0043-1354(98)00020-7

Cited by 41 publications

(23 citation statements)

References 12 publications

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“…Xie (2001) used USEPA Method 552.2 with GC-MS rather than GC-ECD and obtained cleaner baselines with fewer interfering peaks. GC-MS (Berg et al, 2000; Analytical methods for the determination of trichloroethylene 619 REVIEW et al, 1999619 REVIEW et al, , 2000Wong et al, 2003) and GC-ECD LeBel et al, 1997;Dalvi et al, 2000;Benanou et al, 1998;Singer et al, 1995;Krasner et al, 1989) were used to monitor the levels of HAAs in drinking water in the USA, Canada, Switzerland, Saudi Arabia, France and Spain. All methods successfully measured HAAs in drinking water, with limits of detection for DCA and TCA ranging from 0.01 to 4 ng/mL using GC-MS and 0.07 to 0.5 ng/mL using GC-ECD.…”

Section: Gas Chromatographymentioning

confidence: 99%

“…A GC-ECD method also exists for the analysis of TCE in seminal fluids of humans exposed to TCE occupationally (Forkert et al, 2003). There are also several GC-ECD methods for the analysis of HAAs in water LeBel et al, 1997;Dalvi et al, 2000;Benanou et al, 1998;Singer et al, 1995;Krasner et al, 1989) and biological samples (Kim et al, 1999;Wu et al, 2002;Ketcha et al, 1996).…”

Section: Electron Capture Detectionmentioning

confidence: 99%

“…As a result, no methods for the extraction of TCE by SPE were found. Several methods do exist, however, for the analysis of HAAs in water (Benanou et al, 1998;Martínez et al, 1998aMartínez et al, ,b, 1999Loos and Barcelo, 2001;Carrero and Rusling, 1999;Sarzanini et al, 1999) and urine (Kuklenyik et al, 2002;Calafat et al, 2003) using SPE.…”

Section: Solid-phase Extractionmentioning

confidence: 99%

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A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Delinsky

Bruckner

Bartlett

2005

Biomedical Chromatography

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Trichloroethylene (TCE) and some of its metabolites are potentially carcinogenic compounds that the general population is commonly exposed to in drinking water. Concentrations of TCE, dichloroacetic acid (DCA) and trichloroacetic acid (TCA) given to laboratory animals in cancer bioassays are high, whereas drinking water levels of the compounds are very low. It is not clear whether the trace amounts of TCE, DCA and TCA in drinking water pose a cancer risk to humans. The accuracy of pharmacokinetic studies relies on the analytical method from which blood and tissue concentration data are obtained. Models that extrapolate cancer risks of TCE and its metabolites from laboratory animals to humans, in turn, rely on the results of pharmacokinetic studies. Therefore, it is essential to have reliable analytical methods for the analysis of TCE and its metabolites. This paper reviews the methods currently in the literature for the analysis of TCE, DCA, TCA and, to a lesser extent, chloral hydrate (CH). Additional aspects of analytical methods such as method validation, species preservation and future directions in the analysis of TCE and its metabolites are also discussed.

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Section: Gas Chromatographymentioning

confidence: 99%

Section: Electron Capture Detectionmentioning

confidence: 99%

Section: Solid-phase Extractionmentioning

confidence: 99%

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A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Delinsky

Bruckner

Bartlett

2005

Biomedical Chromatography

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“…In 1995 the US EPA published Method 552.2, proposing a liquid-liquid extraction and acidic methanol derivatization technique with final quantification by electron capture detector (GC/ECD). Later on some modifications to these methods were suggested, as performing the extraction and derivatization simultaneously [13] or separately by sample evaporation [14] or by headspace technique. [15] In 1999, a closed-loop stripping analysis (CLSA) technique was employed for the determination of halogenated DBPs using GC-ECD analysis, but only results for DCAA and DBAA were reported.…”

Section: Introductionmentioning

confidence: 99%

Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD

Sá

Boaventura

Pereira

2012

Journal of Environmental Science and Health, Part A

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A solid phase microextraction method was used for the analysis of nine haloacetic acids (HAAs) in water and air (aerosols) from indoor swimming pools (ISPs). The analysis is characterized by derivatization of HAAs to their methyl-esters with dimethyl sulphate, headspace solid phase microextraction (HS-SPME) with a Carboxen-polydimethylsiloxane (CAR-PDMS) fiber and gas chromatography -electron capture detector (GC/ECD). High correlation coefficients were obtained for esters mixture calibration lines and detection limits were found to be at the low ppb level. Repeatability was assessed and coefficients of variation varied from 10 to 20%. Reproducibility was also evaluated and coefficients of variation from 15 to 25% were obtained. Analytical results from four Portuguese ISPs showed that the mean concentration of total HAAs (THAAs) in water ranged from 10 ± 2 to 183 ± 28 µg/L in which 55 ± 20% corresponded to trichloroacetic and dichloroacetic acids (TCAA and DCAA). THAAs highest concentrations were directly related to higher ISPs' water organic matter content. In the lack of European specific regulation for water from ISPs and taking into consideration that ingestion is a form of exposure, THAAs concentration values were compared with drinking water maximum contamination level (MCL) of 60 µg/L proposed by the US EPA for the sum of five HAAs. In 35% of water sampling campaigns the sum of MBAA (monobromoacetic acid), MCAA (monochloroacetic acid), DCAA and TCAA exceeded that MCL value. The concentrations obtained for THAAs in the ISPs' atmosphere ranged from 5 ± 1 to 64 ± 10 µg/m 3 (T = 28 • C at 5 cm above the water surface) and were proportional to the aerosols' quantity, which was deeply related to indoor air ventilation system.

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“…The conditions applied for the analysis were as follows: Hypersil GOLD column (8 μm, 250 mm 21.2 mm i.d.) (Thermo, USA); mobile phase, acetonitrile/ water (20 : 80 v/v) (pH 2.1) containing 10.5 ml phosphoric acid (10%, w/v); flow-rate, 1.0 ml/min; wavelength, 210 nm; and temperature, 25 °C.The medium containing 2-CPA was acidified with phosphoric acid (50:1 v/v), and extracted with methylbutyl ether [12]. The chirality of 2-CPA was determined using a normal phase HPLC method.…”

mentioning

confidence: 99%

Isolation, characterization and identification of a Paracoccus sp. 2‐haloacid‐degrading bacterium from the marine sponge Hymeniacidon perlevis

Huang

Xin

Zhang

2011

J. Basic Microbiol.

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A 2-haloacid dehalogenase-producing bacterium, designated DEH99, was isolated from the marine sponge Hymeniacidon perlevis using a modified enrichment medium and a pH indicator method. DEH99 could degrade only half of the racemic mixture 2-chloropropionic acid (2-CPA) in the medium. The dehalogenase of DEH99 was further determined to be a (S)-2-haloacid dehalogenase, which can degrade 2-CPA, 2-bromopropionic acid (2-BPA), and iodoacetic acid. The gene encoding the (S)-2-haloacid dehalogenase was partially sequenced and classified into the Group II family. The 2-haloacid dehalogenase showed the highest sequence similarity (77% with 21% query coverage) to the haloacid dehalogenase (dhlB) gene of Xanthobacter autotrophicus. A phylogenetic analysis of the 16S rDNA sequence demonstrated that the isolate DEH99 is a member of the genus Paracoccus. To our knowledge, this is the first report detailing the isolation of a strain of genus Paracoccus having 2-haloacid dehalogenase activity from marine sponges.

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Analysis of haloacetic acids in water by a novel technique: simultaneous extraction– derivatization

Cited by 41 publications

References 12 publications

A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD

Isolation, characterization and identification of a Paracoccus sp. 2‐haloacid‐degrading bacterium from the marine sponge Hymeniacidon perlevis

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