Analysis of diagnostic criteria in adamantiades-behçet disease: A retrospective study

Abstract

Adamantiades-Behçet's disease (ABD) is a chronic-relapsing, inflammatory and multi-systemic disease. Any organ or system may be involved: ABD presents a great variety of cutaneous and mucosal lesions, ocular manifestations, central and peripheral nervous system abnormalities, joint as well as gastrointestinal involvement. Since clear pathognomonic clinical features and laboratory tests are lacking, the diagnosis of ABD mainly relies on the characteristic clinical features. Several sets of diagnostic criteria have been used. The International Study Group for Behçet Disease (ISGBD) in 1990 formulated a set of criteria to warrant uniformity of both diagnosis and classification. Therefore, in 2006, a new set was proposed by the International Team for the Revision of the International Criteria for Behçet's Disease (ITR-ICBD) not only to uniform the previous criteria but also to establish best accuracy, along with an optimum sensivity and specificity. The aims of this study are both to analyze the clinical features of ABD patients and to validate the ISGBD and ITR-ICDB criteria for the diagnosis of ABD in our cohort.

Complete heart block in a Caucasian woman with Behçet’s disease: a case report

“…BD is a multisystem inflammatory vasculitis with an unclear etiopathogenesis [ 4 ]. Our patient fulfilled international criteria for BD with oral, genital, and ocular involvement, along with arthritis and cardiovascular inflammation in the presence of intestinal inflammation, while an alternative diagnosis was absent [ 5 ].…”

Behçet’s disease leaves the silk road

“…For more than 16 years the ISG criteria have been the most used criteria for diagnosing BD, however the majority of validation studies failed. Therefore, in 2006, the International Team for the Revision of the International Criteria for Behçet's Disease (ICBD), gathered to establish best accuracy and optimum sensitivity and specificity and created a new set of diagnostic criteria (ICBD) [ 8 ]. Vascular manifestations like superficial phlebitis, deep vein thrombosis, large vein thrombosis, arterial thrombosis and aneurysm were added.…”

Introductory Chapter: Behcet’s Disease - An Overview

“…Genital ulcers and ocular manifestations get two points each. The diagnosis of BD is made when three or more points are collected [37]. Then at 2013, the new criteria were revised under the name International Criteria for Behçet's disease (ICBD).…”