Complete heart block in a Caucasian woman with Behçet’s disease: a case report

Butt, Sabeeh-Ur-Rehman; McNeil, Julian

doi:10.1186/s13256-016-0890-y

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…in Gao et al, and according to the same study prompt management is recommended even with mild conduction disturbance [62,63]. Also arrhythmia such as paroxysmal atrial tachycardia, complex ventricular arrhythmias, premature ventricular beat, or conduction defects as QT dispersion can be found [11,55] Laboratory finding…”

Section: Electrocardiographymentioning

confidence: 91%

Cardiac complication spectrum of Behçet disease in Tunisia: A 10-case series: Clinical and therapeutic approach

Hammami¹,

Jellazi²,

Brahim³

et al. 2020

Preprint

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Introduction:Cardiac involvement (CI), although rare, remains one of the most severe complications of Behçet Disease (BD).Objectiveto investigate the frequency and spectrum of cardiac involvement in BD and to assess the clinical and imaging features, treatment, and outcomes.MethodsWe retrospectively retrieved the medical records of patients with CI among 220 BD patients admitted to the internal medicine department between 2006 and 2016 who fulfilled the International Study Group diagnostic criteria for the classification of BD.ResultsTen patients were eligible for the study with a sex ratio (male/female) of 8/10. Three cases had 2 isolated episodes of cardiac BD. The mean age when diagnosing the first cardiac episode was 37,3-year-old. The different types of CI were: coronary artery disease (5/10), intracardiac thrombus (4/10) myocarditis (1/10), pericarditis (1/10), myocardial fibrosis (1/10). Vascular involvement was associated to CI in 5 cases (50%). The main symptoms were chest pain (80%), fever (60%), dyspnea (50%), cough (10%) and hemoptysis (10%). The laboratory tests revealed increased inflammatory markers in 5 patients. Medical treatment was based on colchicine and corticosteroid in all patients (100%), anticoagulants in 8 patients (80%), Cyclophosphamide followed by Azathioprine in 9 patients (90%), Azathioprine monotherapy was started in one patient (10%). Antiplatelet and anti-ischemic therapy in 5 patients who had coronary artery disease. The evolution was favorable in 9 cases and marked by severe heart failure and the death of one patient.ConclusionCI despite its rarity, remains an important feature of BD due to the increased risk of mortality and morbidity. Thus, early screening and detection are paramount. Also, imaging has been of great contribution to diagnose such complications and hence indicate the adequate treatment, including immunosuppressant agents.

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Section: Electrocardiographymentioning

confidence: 91%

Cardiac complication spectrum of Behçet disease in Tunisia: A 10-case series: Clinical and therapeutic approach

Hammami¹,

Jellazi²,

Brahim³

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…Behcet's disease (BD) is a multi-systemic, inflammatory, and chronic disorder characterized by a triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, uveitis [1,2], and other diverse spectrum of clinical manifestations, including skin, joint, Central Nervous System (CNS), gastrointestinal, pulmonary, and cardiovascular system involvement, which are reported in addition to the major findings of this disorder. Cardiac involvement in BD is known as cardio-Behcet's disease that occurs in 7% to 31% of patients with BD, with a mortality rate of 20% [3].…”

Section: Introductionmentioning

confidence: 99%

Dilated Cardiomyopathy in Behcet′s Disease in a Young Male Patient

Khederlou

Taheri

Sadeghi

et al. 2017

ijcp

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Behcet's disease is a multi-systemic, inflammatory, and chronic disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and other systemic organ involvement. Cardiac involvement in Behcet's disease is rare; however, it plays an important role in prognosis and increases mortality. The current researchers hereby have reported a case of Behcet′s disease with dilated cardiomyopathy. A 28-year-old male patient was presented with constitutional symptoms, oral and genital aphthous ulcers, pseudofolliculitis, tachycardia, arthritis, splenomegaly, erythrocyte sedimentation rate and C-reactive protein elevation, and left ventricular systolic dysfunction with left ventricular ejection fraction of 45%. Azathioprine and prednisolone were begun for the patient.

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Clinical characteristics of conduction disturbance in patients with Behcet’s disease

Gao

Bai

2017

Clin Rheumatol

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To summarized clinical features of Behcet's patients with conduction disturbances and explore the underlying risk factors. A retrospective case-control study was conducted in Anzhen Hospital, Capital Medical University. Demographic data, clinical features, laboratory results, treatments, and fatality rate during hospital stay were analyzed. We found 23.1% of Behcet's disease had conduction disturbances and 84.0% had aortic valvular insufficiency. The male percentage of the Behcet's disease patients with conduction disturbances was significantly higher than controls (88.9 vs. 61.7%, P = 0.03). The echocardiography showed left ventricular end-diastolic diameter [64.00 (18) vs. 48.00 (15) mm, P = 0.000]; left ventricular end-contraction diameter [47.50 (11) vs. 30 (13) mm, P = 0.000]; left atrial diameter [47 (17) vs. 34 (14) mm, P = 0.001]; and left ventricular ejection fraction [60 (10) vs. 63 (13) mm, P = 0.023] were significantly different between two groups. Aortic valvular insufficiency was an independent risk factor for Behcet's disease with conduction disturbances (OR = 17.830; 95% CI 2.106, 150.981; P = 0.008). Conduction disturbance in Behcet's disease deserved attention. The diagnosis of BD and evaluation of conduction disturbance should be kept in mind when accepting patients with valvular regurgitation.

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Complete heart block in a Caucasian woman with Behçet’s disease: a case report

Cited by 5 publications

References 8 publications

Cardiac complication spectrum of Behçet disease in Tunisia: A 10-case series: Clinical and therapeutic approach

Cardiac complication spectrum of Behçet disease in Tunisia: A 10-case series: Clinical and therapeutic approach

Dilated Cardiomyopathy in Behcet′s Disease in a Young Male Patient

Clinical characteristics of conduction disturbance in patients with Behcet’s disease

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