Analysis of chlorotriazines and their degradation products in environmental samples by selecting various operating modes in thermospray HPLC/MS/MS

Abian, Joaquín; Durand, G.; Barceló, Damià

doi:10.1021/jf00032a020

Cited by 73 publications

(44 citation statements)

References 18 publications

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“…Based on our assignment of the daughter ion fragments, the HPLC conditions resulted in HA fragmentation in the enol form (as depicted in Figure 5). The HA mass spectra by electrospray HPLC/MS/MS very closely matched that produced by thermospray HPLC/MS/MS (27).…”

Section: Confirmation Of Hadps In Streamwatersupporting

confidence: 52%

“…Given the results of the HA mass spectra, this was an unexpected finding, but the formation of a [M+2H] parent ion for several triazines by negative mode thermospray HPLC/MS has been reported (27). In addition, the assignment of all major daughter ions could be explained in terms of [M+2H] + parent ion fragmentation.…”

Section: Confirmation Of Hadps In Streamwatermentioning

confidence: 72%

“…Atrazine degradation in a small Iowa stream was postulated to degrade to HA via been shown to occur (44). DEHA and DIHA were also shown to be the major degradation products from photolysis of DEA and DIA in water (27).…”

mentioning

confidence: 99%

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Hydroxylated Atrazine Degradation Products in a Small Missouri Stream

Lerch

Donald

et al. 1996

Herbicide Metabolites in Surface Water and Groundwater

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This research assessed the occurrence of hydroxylated atrazine degradation products (HADPs) in streamwater from Goodwater Creek watershed in the claypan soil region of northeastern Missouri. Streamwater was sampled weekly from June, 1992 to December, 1994 at a V-notch weir used to measure streamflow for this 7250-ha watershed. Filtered water samples were prepared by cation exchange solid-phase extraction and analyzed for hydroxyatrazine (HA), deethylhydroxyatrazine (DEHA), and deisopropylhydroxyatrazine (DIHA) by high performance liquid chromatography with UV detection. HADPs were confirmed by electrospray HPLC/MS/MS and direct probe MS methods. Frequency of HADP detection was 100% for HA, 25% for DEHA, and 6% for DIHA. Concentrations ranged from 0.18-5.7 μg L -1 for HA, <0.12-1.9 μg L -1 for DEHA, and <0.12-0.72 μg L -1 for DIHA. These results establish that HADPs can contaminate surface water and that HA contamination of surface water is a significant fate pathway for atrazine in this watershed.

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Section: Confirmation Of Hadps In Streamwatersupporting

confidence: 52%

Section: Confirmation Of Hadps In Streamwatermentioning

confidence: 72%

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Hydroxylated Atrazine Degradation Products in a Small Missouri Stream

Lerch

Donald

et al. 1996

Herbicide Metabolites in Surface Water and Groundwater

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“…One of the first LC-MS applications to the environmental degradation of pesticides was on chlorotriazines [11]: deisopropylatrazine, deethylatrazine and hydroxyatrazine were identified by LC-TSP MS/MS in positive and [57] and on carbofuran and anilines [12]. The degradation and metabolism of phenoxyacetic acid and diphenyl ether herbicides also mimic their MS/MS fragmentation.…”

Section: Chemical Reactions In the Environmentmentioning

confidence: 99%

Liquid Chromatography Tandem Mass Spectrometry as a Tool to Investigate Pesticides and Their Degradation Products

Medana¹,

Calza²,

Baiocchi³

et al. 2005

COC

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The analytical determination of organic structures is a fundamental need in environmental, food and medicinal chemistry, and the chemistry of pesticide compounds is closely involved in this determination because of the environmental and biological transformations that can occur to these molecules. Degradation products often possess higher toxicity than parent substances but unknown structures, and aqueous milieu produce hard-to-solve instrumental problems. The need to analyze low concentrations in polar solutions means that methods in which liquid chromatography is hyphenated to mass spectrometry have a large playing field, which combines trace determination and structural elucidation. An important area of study comprises degradation-simulating models, such as titanium dioxide mediated photocatalytic attacks on different organic structures. HPLC-mass spectrometric studies on pesticides, their metabolites and their degradation products are reviewed.

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“…However, one should always be aware that, when using these strategies , something has to be known about the unknown' -the unknowns have to be assumed to be unaltered in specific parts of the molecules. Abian et al [80] used the neutral loss mode (42 Da) in a search for triazines and their TPs, desethylatrazine and desisopropylatrazine. Hogenboom et al [76] used the precursor-ion m/z 72 scan mode in on-line SPE -LC -MS -MS search for photodegradation products of diuron and isoproturon in river water ( Figure 12).…”

Section: Ms -Msmentioning

confidence: 99%