Analysis of anti-inflammatory toothpastes efficiency among patients with diabetes mellitus and chronic generalized periodontitis

Subject. The article is a literary review devoted to the peculiarities of clinical manifestations of major dental diseases in patients with impaired carbohydrate metabolism, type 2 diabetes mellitus. Methodology. The data of Russian and foreign literature were studied using scientific search library databases: PubMed, Elibrary, Cochrane. Literature analysis was carried out on 59 sources over the past 5 years (42 domestic authors and 17 foreign ones). The analysis of the literature data allows us to consider type 2 diabetes mellitus as highly common somatic diseases leading to the development of various symptoms, syndromes and diseases of the hard tissues of the teeth, periodontal and oral mucosa. Results. Among the wide range of possible complications and symptoms are - impaired taste sensitivity, the presence of xerostomia, burning mouth syndrome, glossalgia, lichen planus, leukoplakia, candidiasis, chronic inflammatory diseases of periodontal tissues, complicated and uncomplicated caries of hard dental tissues. Diagnostic and therapeutic and preventive measures in this case should be aimed at their early diagnosis and prevention. Conclusions. Against the background of manifestations of DM2, there is a significant prevalence of major dental diseases, which most often depends not only on the duration of the course and severity of DM2, but also on the state of carbohydrate metabolism compensation, age and gender. Undoubtedly, the principle of continuity of interested specialties, including dentists, endocrinologists, gastroenterologists and other specialists, has great prospects both in the diagnosis and prevention of pathology of the oral mucosa.

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Features of Clinical Manifestations of Major Dental Diseases in Patients With Type 2 Diabetes Mellitus (Literature Review)

Senina

Usmanova

Ishmukhametova

et al. 2022

Actual Problems in Dentistry

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Evaluation of the preventive care effectiveness in the adults with odontogenic infection given social and hygienic risk factors

Ulitovskiy

Kalinina

Shevcov

et al. 2021

jour

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Relevance. Odontogenic infection is one of the most important problems of dental science. The variety of anti-inflammatory oral hygiene products determines the need for targeted selection of preventive toothpastes and rinses, balms, foams, elixirs, as well as monitoring and training the algorithm of hygienic measures for a patient with an odontogenic infection. The aim of the study was to study the hygienic status of the adult population for the selection of individual oral hygiene products for odontogenic infection, taking into account social and hygienic factors.Materials and methods. The study examined the prevalence of odontogenic infection in the adult population to determine the need for professional care and dental education. The study involved 198 people without somatic pathology, who were allocated into four groups according to the performed oral care and taking into account the dental status and the intensity of oral microbiota formation in the adult population. The patients were followed-up every week for one month. The study examined the simplified oral hygiene index by GreenVermillion (OHI-S), PMA index and Mühlemann and Son sulcus bleeding index, which allowed calculating the effectiveness of oral care products.Results. The preventive care effectiveness evaluation showed an increase in the cleansing effect in the adult population over the entire study period. The anti-inflammatory effectiveness analysis demonstrated positive changes: by the end of the study, the PMA index was 51.52 ± 3.40% in group 1; it increased by a factor of 3 and amounted to 44.17 ± 2.77% in group 2; 56.51 ± 4.61% – in group 3, 48.95 ± 3.60% – in group 4. The Mühlemann and Son sulcus bleeding index demonstrated the changes in the periodontal tissue condition and amounted to 52.78 ± 3.62% in group 1, 44.11 ± 3.54% in group 2, 54.97 ± 3.98% in group 3, 47.78 ± 2.73% in group 4.Conclusions. The development of oral health promotion measures determines the significance of oral care products for the prevention of odontogenic infection in the adult population, which plays a crucial role in the individual program planning for the main dental disease prevention.

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Experience in the toothpaste’s hygienic effectiveness assessment by oral ﬂuid biochemical parameters

Gromova

Elikov

Ogorodova

et al. 2022

jour

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Relevance. The oral hygiene and prevention quality depends on toothpaste. The literature analysis shows the underuse of saliva biochemical parameters for assessing oral hygiene product effectiveness.Materials and methods. Thirty-three subjects aged 19 to 22 years participated in the study. The participants used four kinds of toothpaste by the same manufacturer to evaluate the toothpaste’s effectiveness. We conducted clinical examinations and collected saliva samples on the 1st, 14th and 28th days of the study. The saliva was collected on an empty stomach without stimulation in the morning. Then it was centrifuged. The supernatant was biochemically studied.Results. The study established the criteria for the toothpaste’s low effectiveness, which involve a signifcant increase in hygienic indices and total antioxidant activity, associated with a statistically signifcant trend towards an increase in lactate content. The criteria for a toothpaste with medium effectiveness are a signifcant decrease in one of the hygienic indices, associated with an alkaline pH shift, and an increase in the total antioxidant activity, without signifcant changes in the lactate content. The criteria for a highly effective toothpaste are a signifcant decrease in hygienic indices, and an alkaline pH shift, associated with a signifcant lactate decrease. Determination of total calcium and inorganic phosphorus in the oral ﬂuid may be crucial for assessing the toothpaste remineralizing properties. The glucose content in mixed saliva yields little information for the toothpaste’s hygienic effectiveness assessment.Conclusion. We can recommend saliva biochemical parameters for assessing the oral hygiene status and the effectiveness of oral hygiene products during oral hygiene product comprehensive studies.

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Analysis of anti-inflammatory toothpastes efficiency among patients with diabetes mellitus and chronic generalized periodontitis

Cited by 6 publications

References 9 publications

Features of Clinical Manifestations of Major Dental Diseases in Patients With Type 2 Diabetes Mellitus (Literature Review)

Features of Clinical Manifestations of Major Dental Diseases in Patients With Type 2 Diabetes Mellitus (Literature Review)

Evaluation of the preventive care effectiveness in the adults with odontogenic infection given social and hygienic risk factors

Experience in the toothpaste’s hygienic effectiveness assessment by oral ﬂuid biochemical parameters

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