Analisis Histopatologi Pembuluh Darah Tikus Berdasarkan Jarak Luka Masuk Pasca Paparan Listrik

Abstract

Electrical injury is damage to the tissues or organs of the body due to the flow of electric current through the body. The Blood vessel is one of the tissues that is damaged when an electrical injury occurs. One of the damages to the blood vessel is the presence of thrombus that can interfere with blood flow and cause the management of electrical injury to be less good. The purpose of this study was to analyze the histopathology of rat blood vessel based on the distance of entry wound after electrical exposure. The type of research was true experimental laboratories with post test only control group design. This study used 25 Wistar strain rats which were divided into five groups. One controlled and the rats in the other four groups were exposed to 140 V electrical potential for 17 seconds. The control group was not exposed to electricity, the H0 group terminated on the 0 th day after the exposure of electricity, the H3 group terminated on the 3 rd -day post electrical exposure, the H7 group terminated on the 7 th -day post electrical exposure, the H10 group terminated on the 10 thday post exposure to electricity. In this study, the percentage of thrombus in the right saphenous artery was observed. Hypothesis accepted if the data analysis using One Way ANOVA or Kruskal Wallis was p <0.05. In this study, it was found that the percentage of thrombus will decrease as the farther from the entry wound, except in the H7 group. Also, the result showed that thrombus percentage increased over time and decreased at a certain time. However, in this study, it was found that there was no statistically significant difference in blood vessels histopathology, especially thrombus based on the distance of entry wound on days 0 Keywords: electrical injury, blood vessel histopathologic, entry wound, thrombus Correspondence to : annisasarfinadj@gmail.com ABSTRAKElectrical injury adalah suatu kerusakan pada jaringan atau organ tubuh akibat adanya aliran arus listrik yang melewati tubuh. Salah satu jaringan yang mengalami kerusakan ketika terjadi electrical injury adalah pembuluh darah yaitu dapat berupa adanya trombus yang dapat mengganggu aliran darah sehingga menyebabkan tatalaksana electric injury menjadi kurang baik. Tujuan umum dari penelitian ini adalah menganalisis histopatologi pembuluh darah tikus berdasarkan jarak luka masuk pasca paparan listrik. Jenis penelitian yang digunakan adalah penelitian eksperimental sebenarnya dengan rancangan post test only control group design. Penelitian ini menggunakan 25 ekor tikus Wistar yang dibagi menjadi lima kelompok. Perlakuan yang diberikan berupa paparan listrik sebesar 140 V selama 17 detik. Kelompok kontrol Laporan Hasil Penelitian