Analgesic, Antiinflammatory and CNS Depressant Activities of Sesquiterpenes (I)—(III) and a Flavonoid Glycoside (IV) from Polygonum viscosum.

Abstract

Terpenes Terpenes U 0200 Analgesic, Antiinflammatory and CNS Depressant Activities of Sesquiterpenes (I)-(III) and a Flavonoid Glycoside (IV) from Polygonum viscosum. -(DATTA, B. K.; DATTA, S. K.; CHOWDHURY, M. M.; KHAN, T. H.; KUNDU, J. K.; RASHID, M. A.; NAHAR, L.; SARKER*, S. D.; Pharmazie 59 (2004) 3, 222-225; Phytopharm. Res. Lab., Sch. Pharm., Robert Gordon Univ., Aberdeen AB10 1FR, UK; Eng.) -R. Langenstrassen 28-184

Bioactivity of Excoecaria agallocha

“…Previous phytochemical studies on E. agallocha revealed the presence of diterpenoids (ISI database, 2008;Ji-Dong et al, 2007;Li et al, 2007;Wang et al, 2006Kang et al, 2005), triterpenoids (Zou et al, 2006), fl avonoid (Konishi et al, 2003) and phorbole esters (Ericson et al, 1995). As part of our continuing phytochemical and bioactivity studies on Bangladeshi medicinal plants and also in other parts of the world (Alam et al, 2008a,b;Ali et al, 2008;Datta et al, 2007Datta et al, , 2004Saha et al, 2007;Uddin et al, 2007aUddin et al, -c, 2006aUddin et al, ,b, 2005Uddin et al, , 2004Rouf et al, 2006;Haque et al, 2004;Rahman et al, 2004;Delazar et al, 2006;Shoeb et al, 2007;Auzi et al, 2007;Zamani et al, 2007;Razavi et al, 2008), we now report on the neuropharmacological and antibacterial activities, and acute toxicty of the ethanol extract of the bark of E. agallocha in laboratory rodents as well as brine shrimp toxicity.…”

Anti-inflammatory activity and toxicological effect of Securidaca longepedunculata (Fresen.) root bark extract in albino rats

“…In literature, there are reports on the anti-inflammatory activity of Persicaria stagnina [10]; Scoparia dulcis [11]; Polygonum viscosum [12]; and Sida cordifolia [13]. In addition, Rashid and Mosaddek [14] reported the anti-inflammatory activity of two Bangladeshi medicinal plants namely Mesua nagassarium and Kigelia pinnata.…”

Further Flavonoids from Polygonum viscosum Buch-Ham. ex D. Don. (Polygonoceae)

“…Polygonaceae), commonly known as Biskatale, is an annual herb (up to 1 meter) native to Nepal and also widely distributed in Bangladesh, northeast India, Japan and China. 1 The genus Polygonum is well known for many pharmacologically active compounds. 2 It is reputed for its application in the oriental systems for the treatment of various diseases such as fever, pain, infections, inflammation, cancer and tumor.…”

“…3 The methanol extract of the plant have yielded several novel flavonoids and a sesqueterpene. 1 This investigation reports the isolation and structure elucidation of three additional flavonoids such as 5,7,4′-trihydroxy-3,8,3′-trimethoxy flavonol (1), 5,7-dihydroxyflavone (2) and 5,6,7-trihydroxyflavone (3). This is the first report of their isolation from the genus Polygonum.…”