2011
DOI: 10.3109/13880209.2010.520322
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Analgesic, anti-inflammatory, and antipyretic activities of the ethanol extract fromDesmodium caudatum

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Cited by 22 publications
(27 citation statements)
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“…Their target cells are present in the immediate vicinity of the site of their secretion. The diversity of receptors means that prostaglandins act on an array of cells and have a wide variety of effects such as relaxation of smooth muscle issue (Nelson, 2005), action on mesangial cells in the glomerulus of the kidney to increase glomerular filtration rate (Vane, 1971;Kim, 2008), and elicitation of pain and inflammation responses (Foegh and Ramwell, 2001;Roberts and Morrow, 2001;Ma et al, 2011).…”
Section: Discussionmentioning
confidence: 98%
“…Their target cells are present in the immediate vicinity of the site of their secretion. The diversity of receptors means that prostaglandins act on an array of cells and have a wide variety of effects such as relaxation of smooth muscle issue (Nelson, 2005), action on mesangial cells in the glomerulus of the kidney to increase glomerular filtration rate (Vane, 1971;Kim, 2008), and elicitation of pain and inflammation responses (Foegh and Ramwell, 2001;Roberts and Morrow, 2001;Ma et al, 2011).…”
Section: Discussionmentioning
confidence: 98%
“…ICR mice were tested by orally administered different doses of the extract. All animals were observed for any gross effect or mortality within 7 days (Ma et al, 2011). The given doses of TGC, TGC-D and TGC-E were up to 2 g/kg, while the control mice were only administered 0.5% CMC-Na at 0.1 mL/10 mg body weight.…”
Section: Acute Toxicity Test In Micementioning
confidence: 99%
“…Hot plate test and tail immersion test are used to assess central analgesic activity [20][21]. Our result demonstrated that MCFL elicited its inhibitory activity by increasing latency time at 120 min that opposed the involvement of opioid.…”
Section: Discussionmentioning
confidence: 74%
“…In the acetic acid-induced writhing test, intraperitoneal injection of acetic acid causes the release of endogenous substances such as PGE2 and PGF2, serotonin and histamine in the peritoneal area. Acetic acid induced increase in prostaglandin E2 and F2α levels in peritoneal fluid excite pain nerve endings [20][21]. MCFL elicited significant analgesic activity in a dose dependent manner when compared with control in acetic acid induced writhing test.…”
Section: Discussionmentioning
confidence: 90%