Anaerobic Transformation of the Iodinated X-ray Contrast Medium Iopromide, Its Aerobic Transformation Products, and Transfer to Further Iodinated X-ray Contrast Media

Redeker, Maria; Wick, Arne N.; Meermann, Björn; Ternes, Thomas A.

doi:10.1021/acs.est.8b01140

Cited by 24 publications

(12 citation statements)

References 63 publications

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“…In approximately this depth, oxygen was depleted (oxygen concentration <1 mg/l). This coincidence indicates redox sensitive degradation of respective TrOCs and was, for example, observed and also previously reported for iomeprol and iopromide (Redeker et al, 2018;Schulz et al, 2008;Zhang et al, 2019). Furthermore, acesulfame, 4-formylaminoantipyrine, metoprolol (Burke et al, 2014), benzotriazole, bezafibrate, gabapentin, and methylbenzotriazole were previously reported to be better attenuated under oxic/suboxic conditions which is in agreement with our findings.…”

Section: Discussionsupporting

confidence: 93%

Seasonal Differences in the Attenuation of Polar Trace Organics in the Hyporheic Zone of an Urban Stream

Mueller

Schulz

Höhne

et al. 2022

Water Resources Research

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Attenuation of trace organic compounds (TrOCs) in a river occurs to a large extent in its hyporheic zone. A major part of the attenuation of polar TrOCs is of microbial origin. As microbial activity depends on temperature and redox conditions, seasonal differences in TrOC attenuation are likely. We investigated TrOC attenuation at a river influenced by treated wastewater during two sampling campaigns, one in summer and one in winter. In addition to redox conditions and temperature, we also determined residence times of porewater in sediment using three methods: (a) non‐parametric deconvolution of electrical conductivity time series, (b) the model VFLUX 2.0 based on temperature time series (only summer), and (c) applying Darcy's law to differences in hydraulic heads (only summer). Contrary to our expectations, we found higher attenuation for 12 out of 18 TrOCs in winter, while three TrOCs were better attenuated in summer. Sediment conditions varied between seasons as more of the top sandy layer with a higher hydraulic permeability accumulated on the river bed in summer. As a result, residence times in the sediment were shorter in summer. In winter, longer residence times, lower temperatures, and a steeper oxygen gradient in sediment coincided with higher TrOC attenuation. Further research is needed to understand our unexpected findings and underlying mechanisms.

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Section: Discussionsupporting

confidence: 93%

Seasonal Differences in the Attenuation of Polar Trace Organics in the Hyporheic Zone of an Urban Stream

Mueller

Schulz

Höhne

et al. 2022

Water Resources Research

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“…The highest removal rate constants were calculated for the iodinated X-ray contrast agents iomeprol (IOM) and IOP. Complete deiodination of both compounds in saturated sediments has only been observed under anoxic redox conditions, but both compounds are known to readily loose side chains of the iodinated ring structure under aerobic conditions. , It is therefore likely that the high removal rates calculated in the present study are due to transformation of both compounds and do not represent complete mineralization. Removal of the artificial sweetener ACS, the lipid-lowering agent bezafibrate (BZF), the anticorrosive agents benzotriazole (BTA) and methylbenzotriazole (MBT), and the anticonvulsant GAB along oxic to suboxic (i.e., denitrifying) flow paths in hyporheic sediments has previously been described in laboratory column experiments , and observed in the HZ .…”

Section: Resultsmentioning

confidence: 67%

Section: ■ Results and Discussionmentioning

confidence: 99%

Fate of Trace Organic Compounds in the Hyporheic Zone: Influence of Retardation, the Benthic Biolayer, and Organic Carbon

Schaper

Posselt

Bouchez

et al. 2019

Environ. Sci. Technol.

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The fate of 28 trace organic compounds (TrOCs) was investigated in the hyporheic zone (HZ) of an urban lowland river in Berlin, Germany. Water samples were collected hourly over 17 h in the river and in three depths in the HZ using minipoint samplers. The four relatively variable time series were subsequently used to calculate first-order removal rates and retardation coefficients via a one-dimensional reactive transport model. Reversible sorption processes led to substantial retardation of many TrOCs along the investigated hyporheic flow path. Some TrOCs such as dihydroxy-carbamazepine, Odesmethylvenlafaxine and venlafaxine were found to be stable in the HZ. Others were readily removed with half-lives in the first 10 cm of the HZ ranging from 0.1±0.01 h for iopromide to 3.3±0.3 h for tramadol. Removal rate constants of the majority of reactive TrOCs were highest in the first 10 cm of the HZ, where removal of biodegradable dissolved organic matter was also highest. Because conditions were oxic along the top 30 cm of the investigated flow path we attribute this finding to the high microbial activity typically associated with the shallow HZ. Frequent and short vertical hyporheic exchange flows could therefore be more important for reach-scale TrOC removal than long, lateral hyporheic flow paths.

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“…For example, Kong et al studied the degradation of IPM by using UV/chlorine, by comparing with UV or chlorine alone 10 , and they found that in contrast to chemical processes, biochemical methods have limited pollutants removal efficiency. For instance, it took over 20 days to achieve more than 95% of IPM degradation by using anaerobic process 11 .…”

Section: Introductionmentioning

confidence: 99%

Fe(II)-activated persulfate oxidation to degrade iopamidol in water: parameters optimization and degradation paths

Dong

Chen

Sun

et al. 2020

Sci Rep

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Iodinated contrast media (ICM), which was widely used in medical imaging and was difficult to remove by conventional wastewater treatment methods, attained much attention due to its potential environmental impacts. Herein, iopamidol (IPM), one typical compound of ICM, was found to be rapidly degraded by ferrous activated persulfate oxidation (Fe(II)/PS) as compared with PS or Fe(II) alone. With a persulfate concentration of 1 mmol L−1, n(Fe(II))/n(PS) of 1:10, and a pH of 3.0, 78% IPM was degraded within 60 min, with a degradation rate of 0.1266 min−1. It was demonstrated that IPM degradation and deiodination were favored by a high temperature, while affected positively by acidic and neutral conditions. Radical quenching experiments and Electron Paramagnetic Resonace (EPR) spectra showed that the combined effects of SO4−· and ·OH contributed dominantly to degrade IPM, while the ·OH played an essential role during the degradation reaction. Through the Discrete Fourier Transform quantum chemical calculation, the possible reaction pathways for the oxidation of IPM by ·OH are as follows: IPM-TP651-TP667-TP541-TP557, IPM-TP651-TP525-TP557, IPM-TP705-TP631-TP661, and IPM-TP705-TP735. The obtained results showed that IPM could be degraded effectively by Fe(II)/PS system, giving a promising technique for IPM removal from water.

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Anaerobic Transformation of the Iodinated X-ray Contrast Medium Iopromide, Its Aerobic Transformation Products, and Transfer to Further Iodinated X-ray Contrast Media

Cited by 24 publications

References 63 publications

Seasonal Differences in the Attenuation of Polar Trace Organics in the Hyporheic Zone of an Urban Stream

Seasonal Differences in the Attenuation of Polar Trace Organics in the Hyporheic Zone of an Urban Stream

Fate of Trace Organic Compounds in the Hyporheic Zone: Influence of Retardation, the Benthic Biolayer, and Organic Carbon

Fe(II)-activated persulfate oxidation to degrade iopamidol in water: parameters optimization and degradation paths

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