Anaemia predicts health related quality of life in heart failure patients

Prevalence of anemia and its influence on hospital readmissions and emergency department visits in outpatients with heart failure

“…19 Severe reductions in Hb and Hct can result from increased plasma volume and impaired erythropoietin activity in CRF. 19,33 In our study, an ejection fraction of less than 40% was associated with anemia. However, some studies have reported that the prevalence of anemia among patients with preserved left ventricular ejection fraction (LVEF) and among those with reduced LVEF is comparable.…”

“…These findings are consistent with those of previous studies. 9,15,16,19,21,[28][29][30][31][32][33][34] Generally, patients with anemia and heart failure tend to be older than patients without anemia and heart failure. [28][29][30] Furthermore, elderly individuals with heart failure are usually unemployed or retired, and therefore have no income.…”

“…These issues lead to a lower quality of life and lower BMI among patients with heart failure and anemia. [31][32][33] Anemia is associated with CRF, increased serum creatinine levels or decreased glomerular filtration rate, decreased BMI, use of ACE inhibitors, and increased jugular venous pressure. 19 Severe reductions in Hb and Hct can result from increased plasma volume and impaired erythropoietin activity in CRF.…”

The clinical epidemiology of fatigue in newly diagnosed heart failure

“…These aberrations have been hypothesized as a direct cause of fatigue and other symptoms in HF, and importantly, both the muscle abnormalities and fatigue have been shown to improve with exercise training [4, 9, 25–27]. Beyond depression and markers of volume regulation and frailty, other notable independent predictors of fatigue were female gender, anemia, sleep apnea, vitamin D deficiency, and higher age – female gender and anemia in particular have shown to be predictors of fatigue in prior studies [4, 6, 17, 28, 29]. …”