Health-related quality of life in outpatients with chronic heart failure associated with sideropenic anemia

Djukic, Biljana; Račić, Maja; Mijović, Biljana; Ivković, Nedeljka

doi:10.1007/s10389-018-0915-7

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…Previous studies found that health -related quality of life, as a treatment outcome, is deteriorated in heart failure 2 , particularly when associated with comorbidities 3,4,5 .Anemia is very common in heart failure, especially in hospitalized patients, females, elder people and those with renal insufficiency. An erythropoietin inhibition occurs on two levels: the kidneys and the bone marrow have the biggest role in the onset of anemia in heart failure.…”

Section: Introductionmentioning

confidence: 99%

“…The damaged myocardium in heart failure produces increased amounts of cytokine tumor necrosis factoralfa, which inhibits the effect of erythropoietin on the progenitor cell of the red blood cell, due to which it prevents the release of iron from the reticuloendothelial system and reduces the hemoglobin synthesis 6 . Anemia may lead to the worsening of heart failure and decline of health-related quality of life of patients suffering from heart failure 4 .…”

Section: Introductionmentioning

confidence: 99%

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Illness perception and treatment adherence in patients with chronic heart failure and sideropenic anemia

Đukić¹,

Račić²,

Pavlović³

et al. 2019

Opšta medicina

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Objective: The primary aim of this study was to examine whether the perception of the patient's disease and adherence to treatment process influence treatment outcomes of heart failure. The secondary aim was to analyze whether there were differences in perception and adherence in patients with heart failure in relation to anemia. Method. A cross-sectional study was carried out in 2015. One group consisted of 100 patients with heart failure and sideropenic anemia. The other group consisted of 100 patients without anemia. The standardized questionnaire was used to collect demographic data, the Brief Illness Perception Questionnaire to measure the patients' perception of the disease and modified Clinician rating scale to assess patient' s adherence. Results: The majority of respondents in the first group were women-63%, while in the second group there were 58% male and 42% female respondents. Respondents from the first group had statistically significantly lower adherence compared to respondents from the second group (χ2 = 23.28; p=0.05). A significant difference was found between the groups of subjects in comparison to the perception of disease control (χ2=18.03; p=0.05). Conclusion: The illness perception and treatment adherence have a significant impact on treatment outcomes of heart failure. Comorbidities, such as anemia, contribute to the patients' perception of their disease and influence their adherence.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Illness perception and treatment adherence in patients with chronic heart failure and sideropenic anemia

Đukić¹,

Račić²,

Pavlović³

et al. 2019

Opšta medicina

View full text Add to dashboard Cite

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The effect of the four pharmacological pillars of heart failure on haemoglobin level

Hullon,

Taherifard,

Al-Saraireh

2024

Annals of Medicine &Amp; Surgery

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Anemia, a condition characterized by low levels of hemoglobin, is frequently observed in patients with heart failure (HF). Guideline-directed medical therapy improves HF outcomes by using medications like beta blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers, along with mineralocorticoid receptor antagonists and sodium-glucose cotransporter 2 inhibitors. In this study, we aimed to review the pathophysiology of anemia in patients with HF and present the current evidence regarding the relationship between the main recommended medications for these patients and hemoglobin levels. We conducted a comprehensive search in the medical literature for relevant original clinical articles in which the four pharmacological pillars of HF were given to the patients; we, then, assessed whether the association of use of these medications and hemoglobin level or development of anemia was provided. These common medications have been shown in the literature that may exacerbate or ameliorate anemia. Besides, it has been shown that even in the case that they result in the development of anemia, their use is associated with positive effects that outweigh this potential harm. The literature also suggests that among patients receiving medications with negative effects on the level of hemoglobin, there was no difference in the rate of mortality between anemic and non-anemic patients when both were on treatment for anemia; this point highlights the importance of the detection and treatment of anemia in these patients. Further research is needed to explore these relationships and identify additional strategies to mitigate the risk of anemia in this population.

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Health-related quality of life in outpatients with chronic heart failure associated with sideropenic anemia

Cited by 2 publications

References 28 publications

Illness perception and treatment adherence in patients with chronic heart failure and sideropenic anemia

Illness perception and treatment adherence in patients with chronic heart failure and sideropenic anemia

The effect of the four pharmacological pillars of heart failure on haemoglobin level

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