An Unusual Location of Juvenile Angiofibroma: A Case Report and Review of the Literature

Maheshwarappa, Ravishankar Pillenahalli; Gupta, Amit; Bansal, Juhi; Kattimani, Mahesh Virupaksha; Shabadi, Sachin Shivayogappa; Baser, Suresh Chandra

doi:10.1155/2013/175326

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…Epistaxis, unilateral nasal obstruction, pain and facial deformities are the most common symptoms associated with nasopharyngeal angiofibroma. They show connective tissue stroma with multiple vascular channels on histopathology 1. Surgery is required for the management of nasopharyngeal angiofibroma.…”

Section: Descriptionmentioning

confidence: 99%

Juvenile nasopharyngeal angiofibroma

et al. 2022

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Section: Descriptionmentioning

confidence: 99%

Juvenile nasopharyngeal angiofibroma

et al. 2022

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“…There are many theories trying to explain the pathology underlying this tumor, like genetic, hormonal, and developmental ones, but none of them had general acceptance. It has been hypothesized that angiofibroma is a testosterone-dependent tumor that arises from a fibrovascular nidus in the nasopharynx that lies dormant until the onset of puberty; hence the incidence is more in males with peak incidence between the ages of 14 and 18 years [1]. Histologically, angiofibroma is made up of fibrous and vascular components, with varying ratio between both of them.…”

Section: Introductionmentioning

confidence: 99%

“…Mostly, the vessels are just endothelium-lined spaces without muscle coat, and that accounts for the severe bleeding as the vessels lose the ability to contract [2]. It is the most common vascular neoplasm of the nasal cavity, representing 0.5% of all head and neck tumors [1, 3, 4]. Although it is a benign tumor, it is locally invasive.…”

Section: Introductionmentioning

confidence: 99%

“…Despite the fact that it most commonly arises from the nasopharynx, it may rarely arise in extranasopharyngeal sites, like maxillary sinus which is the most common site (24.6%–32%) [4–7]. Other rare reported sites include ethmoid and sphenoid sinuses, nasal septum, middle turbinate, inferior turbinate, conjunctiva, molar and retromolar region, and tonsil and larynx [1]. Here, we report a very rare case of extranasopharyngeal angiofibroma originating from the lateral wall of the left nasal vestibular area.…”

Section: Introductionmentioning

confidence: 99%

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Angiofibroma Originating outside the Nasopharynx: A Management Dilemma

Mahmood

Sheikh

Saey

et al. 2016

Case Reports in Otolaryngology

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Background. Angiofibroma is a benign tumor, consisting of fibrous tissue with varying degrees of vascularity, characterized by proliferation of stellate and spindle cells around the blood vessels. It most commonly arises from the nasopharynx, although it may rarely arise in extranasopharyngeal sites. Case Report. A 46-year-old male presented with left side nasal obstruction and epistaxis for one month. Clinical nasal examination revealed left sided polypoidal mass arising from the vestibular region of the lateral nasal wall. Results. CT scan and MRI showed highly vascular soft tissue mass occupying the anterior part of the left nostril. Preoperative selective embolization followed by transnasal excision was performed. Histopathological examination confirmed the diagnoses of nasal vestibular angiofibroma. Conclusion. Extranasopharyngeal angiofibroma is a very rare pathology. It should be kept in mind as a differential diagnosis with any unilateral nasal vestibular mass causing nasal obstruction and epistaxis. A biopsy without further investigation can cause life threatening bleeding in the patient.

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Angiofibroma of the maxillary sinus mimicking mucocele: a diagnostic challenge

Cheah,

Lim,

Japar

et al. 2023

Egypt J Otolaryngol

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Background Angiofibroma is a rare, histologically benign but locally aggressive vascular tumour that typically arises within the nasopharynx. Angiofibroma in sites other than the nasopharynx is extremely uncommon. Despite the histological similarities, the clinical features of this tumour are very much different from the typical nasopharyngeal angiofibroma and pose a diagnostic challenge, hence emphasizing the importance of a thorough evaluation and high index of suspicion in establishing the correct diagnosis. Case presentation A 25-year-old gentleman presented with progressive right nasal blockage and intermittent nasal discharge for 3 years duration. He was clinically and radiologically diagnosed as a mucocele. Surgical excision was done via endoscopic medial maxillectomy with complete relief of all the symptoms. Conclusion Although uncommon, angiofibroma can occur outside the nasopharynx. Therefore, thorough evaluation and a high index of suspicion are crucial in establishing the correct diagnosis.

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An Unusual Location of Juvenile Angiofibroma: A Case Report and Review of the Literature

Cited by 5 publications

References 8 publications

Juvenile nasopharyngeal angiofibroma

Juvenile nasopharyngeal angiofibroma

Angiofibroma Originating outside the Nasopharynx: A Management Dilemma

Angiofibroma of the maxillary sinus mimicking mucocele: a diagnostic challenge

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