Patient: Male, 25Final Diagnosis: Nasal type • extra nodal NK/T-cell lymphomaSymptoms: Left periorbital swelling • redness • pain for 25 days • yellowish eye discharge associated • headache • feverMedication: —Clinical Procedure: —Specialty: OtolaryngologyObjective:Unusual clinical courseBackground:Extranodal lymphoma of the paranasal sinuses is a rare clinical entity seen in only 5–8% of extranodal lymphomas of the head and neck. Nasal natural killer/T cell lymphoma (Nasal NKTCL), which is a subtype of peripheral T cell lymphoma, constitutes about 1.4% of all lymphomas. NKTCL is usually diagnosed at a late stage because it presents with nonspecific symptoms in the early stages.Case Report:We report the case of a 25-year-old male patient who presented with periorbital swelling treated as fungal sinusitis but proven to have NKTCL. We review the literature and discuss the clinical manifestations of the disease, its relation to EBV virus, the histological and radiological characteristics, the prognostic indicators, and treatment options. This case report shows physicians that NKTCL lymphoma can present as periorbital cellulitis, although few similar cases are found in the literature.Conclusions:NKTCL is a destructive midline tumor that should be kept in mind as a differential diagnosis of paranasal sinus lesions to help in early diagnosis, which can improve the prognosis.
Background. Angiofibroma is a benign tumor, consisting of fibrous tissue with varying degrees of vascularity, characterized by proliferation of stellate and spindle cells around the blood vessels. It most commonly arises from the nasopharynx, although it may rarely arise in extranasopharyngeal sites. Case Report. A 46-year-old male presented with left side nasal obstruction and epistaxis for one month. Clinical nasal examination revealed left sided polypoidal mass arising from the vestibular region of the lateral nasal wall. Results. CT scan and MRI showed highly vascular soft tissue mass occupying the anterior part of the left nostril. Preoperative selective embolization followed by transnasal excision was performed. Histopathological examination confirmed the diagnoses of nasal vestibular angiofibroma. Conclusion. Extranasopharyngeal angiofibroma is a very rare pathology. It should be kept in mind as a differential diagnosis with any unilateral nasal vestibular mass causing nasal obstruction and epistaxis. A biopsy without further investigation can cause life threatening bleeding in the patient.
More than 90% of malignant tumors of the larynx are squamous cell carcinomas. Extramedullary plasmacytoma is a plasma cell tumour representing less than 1 % of all head and neck malignancies and involvement of the larynx is very rare. In the larynx the supraglottis is the primary site of involvement compared to the glottic and subglottic regions. We report a case of 54-yearold Indonesian female who presented at our clinic with stridor as primary manifestation secondary to solitary extramedullar plasmacytoma involving the glottis and subglottis of the larynx. The patient underwent microlaryngoscopy, biopsy and CO2 laser excision of the tumour with significant improvement of the airway and was referred for locoregional radiotherapy. We review the literature and discuss the management of this rare condition.
Given the overlapping clinical features of sino‐nasal immunoglobulin 4‐related disease (IgG4‐RD) to rhinitis or rhinosinusitis, this paper aims to delineate this rare, isolated manifestation significant to physicians for their daily practice and researchers contributing to this field.
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