2011
DOI: 10.1590/s1413-86702011000100004 View full text |Buy / Rent full text
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Abstract: Cutaneous leishmaniasis (CL) is a widespread tropical infection which has a high incidence rate in Iran. Leishmania tropica, the causative agent of anthroponotic cutaneous leishmaniasis (ACL), and Leishmania major, which causes zoonotic cutaneous leishmaniasis (ZCL), are endemic in various parts of Iran with a high incidence rate. The aim of this study was to evaluate the reappraisal of the diagnosis and epidemiology of CL in Iran, by different clinical, parasitological and molecular assays among patients susp… Show more

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“…These finding are similar to those of Al-Tawfiq and Abu Khamsin [7]. Most recent epidemiological studies in Yemen, Saudi Arabia and Israel revealed a similar trend, with single lesions on the face or limbs being the most common form of presentation [7,[9][10][11][12].…”
Section: Resultssupporting
“…Leishmaniasis of the skin may occur anywhere on the body but the usual sites are the exposed parts. Most patients have one or two ulcers, but the lesions may be multiple with various presentations (8). The cases of isolated lip leishmaniasis are seldom reported from Iran (9).…”
Section: Discussionmentioning
“…The culture was incubated at 25°C and checked for growth of Leishmania promastigotes for 28 days. Penicillin-G and streptomycin were added to the phosphate buffered saline (PBS) solution utilized in the NNN media culture (Eisenberger and Jaffe, 1999;Farahmand et al, 2008).…”
Section: Culturementioning
“…[9] The history of vaccination with the virulent forms of Leishmania called as leishmanization dates back to early 20th century but due to safety concerns it was banned for trial in human models; first generation vaccine was limited by the immunity conferred by it as it was effective in Sudan (VL) and Iran (CVL) but was not a suitable candidate in Brazil, second generation vaccines are in trial and are useful in providing protection of varying levels in different species along with the DNA and other subunit vaccines.…”
Section: Introductionmentioning
“…In this group Leishmania major is the etiological agent of cutaneous leishmaniasis that is prevalent in many tropical and subtropical areas of the world. The disease has a high incidence rate in Iran (Alvar et al 2012;Farahmand et al 2011). The manifestation of disease is varying from self-limiting with life-long immunity to developing shape as chronic disease.…”
Section: Introductionmentioning