An Investigation of Topics and Trends of Tracheal Replacement Studies Using Co-Occurrence Analysis

Abstract

This study evaluated tracheal regeneration studies using scientometric and co-occurrence analysis to identify the most important topics and assess their trends over time. To provide the adequate search options, PubMed, Scopus, and Web of Science (WOS) were used to cover various categories such as keywords, countries, organizations, and authors. Search results were obtained by employing Bibexcel. Co-occurrence analysis was applied to evaluate the publications. Finally, scientific maps, author's network, and country contributions were depicted using VOSviewer and NetDraw. Furthermore, the first 25 countries and 130 of the most productive authors were determined. Regarding the trend analysis, 10 co-occurrence terms out of highly frequent words were examined at 5-year intervals. Our findings indicated that the field of trachea regeneration has tested different approaches over the time. In total, 65 countries have contributed to scientific progress both in experimental and clinical fields. Special keywords such as tissue engineering and different types of stem cells have been increasingly used since 1995. Studies have addressed topics such as angiogenesis, decellularization methods, extracellular matrix, and mechanical properties since 2011. These findings will offer evidence-based information about the current status and trends of tracheal replacement research topics over time, as well as countries' contributions.

A Bibliometric Analysis of the Impacts of Air Pollution on Children

“…Overall, 15,999 articles in research were published by 8425 institutions. Fifteen institutes were selected because of their critical role for scientific knowledge dissemination [19,20]. The list of top 15 institutions is presented in Table 2, which published about 24.81% of all the articles.…”

Mesenchymal stem cell (MSC)-derived exosomes as a cell-free therapy for patients Infected with COVID-19: Real opportunities and range of promises

“…Exosome-based therapy is an attractive strategy for achieving the therapeutic benefits of MSCs without the complications and difficulties of the cells to the patients. In particular, the possible use of exosomes in preclinical models to alleviate ARDS is well known ( Ghorbani et al, 2017 ).…”

Mechanical Evaluation of Tracheal Grafts on Different Scales

“…Recently, there has been an increasing number of works related to tracheal regeneration . This article aimed to elucidate a better understanding of the mechanical evaluations of tracheal grafts for basic research.…”