An intelligent face mask integrated with high density conductive nanowire array for directly exhaled coronavirus aerosols screening

Xue, Qiannan; Kan, Xinyuan; Pan, Zhihao; Li, Zheyu; Pan, Wenwei; Zhou, Feng; Duan, Xuexin

doi:10.1016/j.bios.2021.113286

Cited by 51 publications

(45 citation statements)

References 38 publications

(31 reference statements)

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“…With the use of nanowires, there are advantages such as ultra-low power consumption; small size; rapid response; high sensitivity; and being non-hazardous, easy to use, non-invasive, stored well and not that costly. For the management and detection of respiratory infections, a sensitive and affordable POC tool was provided as a combination of nanoscale sensors and a face mask [ 157 ].…”

Section: Discussionmentioning

confidence: 99%

Biosensors as Nano-Analytical Tools for COVID-19 Detection

Pradhan

Lahare

Sinha

et al. 2021

Sensors

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Selective, sensitive and affordable techniques to detect disease and underlying health issues have been developed recently. Biosensors as nanoanalytical tools have taken a front seat in this context. Nanotechnology-enabled progress in the health sector has aided in disease and pandemic management at a very early stage efficiently. This report reflects the state-of-the-art of nanobiosensor-based virus detection technology in terms of their detection methods, targets, limits of detection, range, sensitivity, assay time, etc. The article effectively summarizes the challenges with traditional technologies and newly emerging biosensors, including the nanotechnology-based detection kit for COVID-19; optically enhanced technology; and electrochemical, smart and wearable enabled nanobiosensors. The less explored but crucial piezoelectric nanobiosensor and the reverse transcription-loop mediated isothermal amplification (RT-LAMP)-based biosensor are also discussed here. The article could be of significance to researchers and doctors dedicated to developing potent, versatile biosensors for the rapid identification of COVID-19. This kind of report is needed for selecting suitable treatments and to avert epidemics.

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Section: Discussionmentioning

confidence: 99%

Biosensors as Nano-Analytical Tools for COVID-19 Detection

Pradhan

Lahare

Sinha

et al. 2021

Sensors

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“…In approximately 5 min, viral concentrations as low as 7 pfu/mL were detected from an atomized sample of coronavirus aerosol mimic. The POC systems can be used on-site for basic screening of coronavirus infections and may aid in understanding the course of COVID-19 while a patient is on treatment [90]. A cotton-tipped electrochemical immunosensor for detecting the virus antigen of the SARS-CoV-2 was developed by Eissa et al [90].…”

Section: Wearable Microfluidic and Smart (Nano)biosensorsmentioning

confidence: 99%

A review on corona virus disease 2019 (COVID-19): current progress, clinical features and bioanalytical diagnostic methods

2022

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A new epidemic of acute respiratory viral pneumonia was discovered in central China at the end of 2019. The disease was given the name coronavirus disease 2019 (COVID-19), and the virus that caused this disease was known as severe acute respiratory syndrome coronavirus (SARS-CoV-2). So far, diagnostic methods have been focused on (a) human antibody detection, (b) viral antigen detection and (c) viral gene detection, the latter using RT-PCR being the most accurate approach. In this paper, we present a summary of the COVID-19 pandemic, clinical features and epidemiology and pathogenesis. Also, we focus on the recent advances in bioanalytical diagnostic methods based on various techniques for SARS-CoV-2 sensing that have recently been published (2020)(2021). Furthermore, we present the mechanisms, advantages and disadvantages of the most common biosensors for COVID-19 detection, which include optical, electrochemical and piezoelectric biosensors as well as wearable and smart nanobiosensors, immunosensors, aptasensors and genosensors.

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“…Based on micro/nano technologies and the principle of immunoassay, some POCT platforms are constructed directly for detection of infectious pathogens waiving nucleic acid amplifications. Integrating the detection devices into wearables can expand opportunities for long-term and noninvasive monitoring of infections [ 158 , 159 ]. Xue et al reported an intelligent wearable face mask integrated with a flexible immunosensor for highly sensitive screening of exhaled coronavirus aerosols.…”

Section: Micro/nano Devices For Point-of-care Testing Of Sars-cov-2mentioning

confidence: 99%

Micro/nano biomedical devices for point-of-care diagnosis of infectious respiratory diseases

Wang

Dong

et al. 2022

Medicine in Novel Technology and Devices

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Corona Virus Disease 2019 (COVID-19) has developed into a global pandemic in the last two years, causing significant impacts on our daily life in many countries. Rapid and accurate detection of COVID-19 is of great importance to both treatments and pandemic management. Till now, a variety of point-of-care testing (POCT) approaches devices, including nucleic acid-based test and immunological detection, have been developed and some of them has been rapidly ruled out for clinical diagnosis of COVID-19 due to the requirement of mass testing. In this review, we provide a summary and commentary on the methods and biomedical devices innovated or renovated for the quick and early diagnosis of COVID-19. In particular, some of micro and nano devices with miniaturized structures, showing outstanding analytical performances such as ultra-sensitivity, rapidness, accuracy and low cost, are discussed in this paper. We also provide our insights on the further implementation of biomedical devices using advanced micro and nano technologies to meet the demand of point-of-care diagnosis and home testing to facilitate pandemic management. In general, our paper provides a comprehensive overview of the latest advances on the POCT device for diagnosis of COVID-19, which may provide insightful knowledge for researcher to further develop novel diagnostic technologies for rapid and on-site detection of pathogens including SARS-CoV-2.

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An intelligent face mask integrated with high density conductive nanowire array for directly exhaled coronavirus aerosols screening

Cited by 51 publications

References 38 publications

Biosensors as Nano-Analytical Tools for COVID-19 Detection

Biosensors as Nano-Analytical Tools for COVID-19 Detection

A review on corona virus disease 2019 (COVID-19): current progress, clinical features and bioanalytical diagnostic methods

Micro/nano biomedical devices for point-of-care diagnosis of infectious respiratory diseases

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