An Improved, Highly Efficient Method for the Synthesis of Bisphenols

Boron-doped diamond electrode has been utilized for the study of electrochemical behaviour of an anti-HIV herbal drug wedelolactone in Britton-Robinson buffer (pH-2.5) by square-wave and cyclic voltammetry techniques. The response characteristics of cyclic voltammetry and square wave voltammetry showed a remarkable increase in the anodic peak current and electrochemical impedance spectroscopy revealed a lowering in charge transfer resistance at the boron-doped diamond electrode as compared to the glassy carbon electrode that can be attributed to the higher sensitivity of boron-doped diamond sensor. Cyclic voltammetry at the boron-doped diamond surface revealed the oxidation of wedelolactone with two oxidation peaks (P 1 and P 2 ) with Ep 1 = 0.4V and Ep 2 =1.00 V with scan rate varying from 10 -220 mV/s and exhibits diffusion-controlled process. Based on the electrochemical measurements, a probable oxidation mechanism has been deduced and the electrode dynamics parameters have been evaluated. The effect of concentration on the peak currents of wedelolactone was found to have a linear relationship within the concentration range of 50-700 ng/mL. The LOD and LOQ were found to be 43.87 and 132.93 ng/mL respectively. The applicability of the proposed method was further scrutinized by the successful determination of wedelolactone in real plant samples.

show abstract

“…54,55 Table 3 reveals that the present method is more sensitive and the detection limit of WDL is lower than check the reported methods.…”

Section: Comparison Of the Sensitivity Of The Present Work With Othermentioning

confidence: 65%

Voltammetric determination of wedelolactone, an anti-HIV herbal drug, at boron-doped diamond electrode

2015

View full text Add to dashboard Cite

show abstract

“…ES powder was used as a catalyst for the synthesis of Schiff bases under solvent free conditions. 18 These will bond coordinately with metals to form metal complexes and are used as models for biological systems. 19 Numerous research studies have explored the synthesis of Schiff bases, 20,21 but they faced constraints such as long reaction time, low yield, use of toxic solvents and tedious workup procedures.…”

Section: Schiff Base Synthesismentioning

confidence: 99%

Biogenic derived egg shell and its derivatives as solid base heterogeneous catalysts for organic transformations: a comprehensive review

Naik,

Divakar,

M. S.

et al. 2024

RSC Sustain.

View full text Add to dashboard Cite

show abstract

“…Schiff bases are a significant denomination of ligands retaining vast scope of applications. [1] Schiff base ligands participate in physiological and pharmacological fields, in addition, they act as chelating agents, and the metal ions are bound to give metal chelates that have been employed in biological studies. [2] Also, transition metal chelates are employed in food manufacture, biology, synthesis of dyes, and analytical chemistry.…”

Section: Introductionmentioning

confidence: 99%

Bivalent Metal Chelates with Pentadentate Azo‐Schiff Base Derived from Nicotinic Hydrazide: Preparation, Structural Elucidation, and Pharmacological Activity

Abouel‐Enein

Emam

Abdel‐Satar

2023

Chemistry & Biodiversity

View full text Add to dashboard Cite

Azo‐Schiff base ligand (N′‐((E)‐2‐hydroxy‐5‐((E)‐(2‐hydroxyphenyl)diazenyl)benzylidene)nicotinohydrazide) and its Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Pd(II) chelates were prepared and elucidated. The geometrical structures of the prepared chelates were characterized by several spectroanalytical techniques and thermogravimetric analysis. The obtained data revealed that the chelates have (1M:1L), (1M:2L), (1M:3L), and (1M:4L) molar ratios. The infrared spectra displayed that the H2L ligand behaves in a pentacoordinate fashion in chelates of Mn(II), Ni(II), and Cu(II) ions. However, in Zn(II) and Pd(II) chelates, the ligand is coordinated as a tetradentate species (NONO) through nitrogen atoms of azomethine and azo groups as well as oxygen atoms of phenolic hydroxy, and carbonyl groups. Besides, it was concluded that the oxygen atoms of carbonyl and hydroxy groups along with the azomethine nitrogen atom of the ligand are bounded with Co(II) ion in metal chelate (2). According to the measured molar conductance values, the chelates of Cu(II), Zn(II), and Pd(II) are weak electrolytes, but Mn(II), Co(II), and Ni(II) chelates are ionic. The azo‐Schiff base ligand and its prepared metal chelates were tested for their antioxidant and antibacterial properties. The Ni(II) chelate was found to be considered an effective antioxidant agent. In addition, the available antibacterial data suggest that the Ni(II) and Co(II) chelates may be employed as inhibitor agents against Proteus vulgaris, Escherichia coli, and Bacillus subtilis bacteria. Furthermore, the data showed that, in comparison to the ligand and other metal chelates, copper(II) chelate (4) exhibited higher action against Bacillus subtilis bacteria.

show abstract

An Improved, Highly Efficient Method for the Synthesis of Bisphenols

Abstract: An efficient synthesis of bisphenols is described by condensation of substituted phenols with corresponding cyclic ketones in presence of cetyltrimethylammonium chloride and 3-mercaptopropionic acid as a catalyst in extremely high purity and yields.

Cited by 7 publications

References 2 publications

Voltammetric determination of wedelolactone, an anti-HIV herbal drug, at boron-doped diamond electrode

Voltammetric determination of wedelolactone, an anti-HIV herbal drug, at boron-doped diamond electrode

Biogenic derived egg shell and its derivatives as solid base heterogeneous catalysts for organic transformations: a comprehensive review

Bivalent Metal Chelates with Pentadentate Azo‐Schiff Base Derived from Nicotinic Hydrazide: Preparation, Structural Elucidation, and Pharmacological Activity

Contact Info

Product

Resources

About