“…The observation in the present study of the predominance of cells expressing IgG might indicate that lacaziosis, as a chronic infectious disease, suffer a constant antigen stimulus, as previously considered. In frozen histological sections analyzed by immunofluorescence staining, deposits of C3, IgG and IgM were observed in the fungal wall of 100%, 91% and 18% of the lesions, respectively 20 .…”