An Ethnobotanical Study of Medicinal Plants With Antianxiety and Antidepressant Effects in Shahrekord

Abbaszadeh, Sepideh; Teimouri, Hassan; Farzan, Behrooz

doi:10.21608/ejvs.2019.12612.1077

Cited by 8 publications

(6 citation statements)

References 23 publications

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“…Medicinal plants which can be used as tools against anxiety and as antidepressant drugs according to the ethnobotanical knowledge in Shahrekord (Iran) include M. officinalis, proven to be effective on anxiety and depression [29]. In the Unani system of medicine, its grass and seeds are used in epilepsy, paralysis, Bell's palsy, arthritis, mastitis, and halitosis; its syrup and distillate are made for different ailments [30].…”

Section: Traditional Medicinal Usesmentioning

confidence: 99%

[Retracted] Phytochemical Constituents, Biological Activities, and Health‐Promoting Effects of the Melissa officinalis

Sharifi‐Rad

Quispe

Herrera‐Bravo

et al. 2021

Oxidative Medicine and Cellular Longevity

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Medicinal plants are being used worldwide for centuries for their beneficial properties. Some of the most popular medicinal plants belong to the Melissa genus, and different health beneficial effects have already been identified for this genus. Among these species, in particular, the Melissa officinalis L. has been reported as having many biological activities, such as antioxidant, antimicrobial, antitumour, antiviral, antiallergic, anti-inflammatory, and also flatulence inhibiting effects. The beneficial properties of the Melissa officinalis, also known as “lemon balm herb”, can be related to the bioactive compounds such as terpenoids, alcohols, rosmarinic acid, and phenolic antioxidants which are present in the plant. In this updated review, the botanical, geographical, nutritional, phytochemical, and traditional medical aspects of M. officinalis have been considered as well as in vitro and in vivo and clinically proven therapeutic properties have been reviewed with a special focus on health-promoting effects and possible perspective nutraceutical applications. To evidence the relevance of this plant in the research and completely assess the context, a literature quantitative research analysis has been performed indicating the great interest towards this plant for its beneficial properties.

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Section: Traditional Medicinal Usesmentioning

confidence: 99%

[Retracted] Phytochemical Constituents, Biological Activities, and Health‐Promoting Effects of the Melissa officinalis

Sharifi‐Rad

Quispe

Herrera‐Bravo

et al. 2021

Oxidative Medicine and Cellular Longevity

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“…From the aqueous extract of D. ismaelis' aerial parts, four isoflavone glycosides, including daidzin (20), genistin (21), daidzein-4 -O-β-D-glucopyranoside (22) and prunetrin (23), have been isolated. Moreover, two chalcones, including a new compound ismaeloside A (25) and isobavachalcone (24), have been isolated [54].…”

Section: Flavonoidsmentioning

confidence: 99%

“…The in vitro anti-osteoporotic activities of some secondary metabolites of D. ismaelis were determined by utilizing the TRAP (tartrate-resistant acid phosphatase) method. (Z)-Plicatin B (44), citrusin C (39), daidzein-4 -O-β-d-glucopyranoside (22) and liriodendrin (34) suppressed osteoclast formation with TRAP values of 86.05%, 100.93%, 104.77% and 106.05% of the control, respectively, at a concentration of 10 µM, considering that daidzein as the positive control had an inhibition of 131% at the same concentration [54].…”

Section: Anti-osteoporotic Activitymentioning

confidence: 99%

“…The aerial parts of D. anethifolia have been traditionally used to relieve headache, backache and colic pain in Asian countries, particularly Afghanistan, Iran, Iraq, Pakistan and Lebanon [4,[15][16][17][18][19][20][21]. The effects of the aerial parts of D. anethifolia on the central nervous system were also reported, especially its use as anxiolytic, antidepressant and in treating insomnia [17,[21][22][23]. For this plant, the following traditional applications have also been documented: treatment of cold [7,17,21,24], heartburn [21] and inflammation of the inner wall of the nose [7], and as an analgesic [4,17,18,20,25], a flavoring in food [4,23,[26][27][28][29][30] and an insecticide [7,17,21,24].…”

Section: Introductionmentioning

confidence: 99%

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Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review

et al. 2020

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The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1‒74.0%) and dodecanal (7.2‒33.41%), and α-pinene (4.0‒70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants.

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“…Earlier reports show that the plant possesses different pharmacological effects. Some of the activities reported include anti-diabetic and antiulcer effects ( Unissa Syed et al., 2022 ), analgesic, central nervous system depressant actions such as anti-anxiety, sedative, and anti-depressant effects ( Abbaszadeh et al., 2019 ), carminative, relief of colic pain and as a flavoring agent ( Mottaghipisheh et al., 2020 ). Further there are reports on phytoconstituents present in Ducrosia anethifolia showing antibacterial activity against MRSA ( Mahboubi et al., 2014 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of Ducrosia anethifolia methanol extract against methicillin resistant Staphylococcus aureus and Pseudomonas aeruginosa biofilms on excision wound in diabetic mice

Almuhanna

2024

Front. Cell. Infect. Microbiol.

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BackgroundDucrosia anethifolia is an aromatic desert plant used in Saudi folk medicine to treat skin infections. It is widely found in Middle Eastern countries.MethodsA methanolic extract of the plant was prepared, and its phytoconstituents were determined using LC-MS. In-vitro and in-vivo antibacterial and antibiofilm activities of the methanolic extract were evaluated against multidrug-resistant bacteria. The cytotoxic effect was assessed using HaCaT cell lines in-vitro. Diabetic mice were used to study the in-vivo antibiofilm and wound healing activity using the excision wound method.ResultsMore than 50 phytoconstituents were found in the extract after LC-MS analysis. The extract exhibited antibacterial activity against both the tested pathogens. The extract was free of irritant effects on mice skin, and no cytotoxicity was observed on HaCaT cells with an IC50 value of 1381 µg/ml. The ointment formulation of the extract increased the healing of diabetic wounds. The microbial load of both pathogens in the wounded tissue was also reduced after the treatment. The extract was more effective against methicillin-resistant Staphylococcus aureus (MRSA) than MDR-P. aeruginosa in both in vitro and in vivo experiments. Further, skin regeneration was also observed in histological studies.ConclusionsThe results showed that D. anethifolia methanol extract supports wound healing in infected wounds in diabetic mice through antibacterial, antibiofilm, and wound healing activities.

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An Ethnobotanical Study of Medicinal Plants With Antianxiety and Antidepressant Effects in Shahrekord

Cited by 8 publications

References 23 publications

[Retracted] Phytochemical Constituents, Biological Activities, and Health‐Promoting Effects of the Melissa officinalis

[Retracted] Phytochemical Constituents, Biological Activities, and Health‐Promoting Effects of the Melissa officinalis

Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review

Effect of Ducrosia anethifolia methanol extract against methicillin resistant Staphylococcus aureus and Pseudomonas aeruginosa biofilms on excision wound in diabetic mice

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