A NXIETY and depression are two highly prevalent disorders in all human communities.The purpose of the present study was to report medicinal plant species that local people, according to their ethnobotanical knowledge, in Shahrekord use as antianxiety and antidepressant agents. The present ethnobotanical study was carried out to report and collect indigenous knowledge in the studied region in 2017 via face-to-face interviews and by using a questionnaire distributed among 29 traditional therapists. To this end, interviewers referred to respondents in person to elicit their pharmacological and ethnobotanical knowledge, and then register their viewpoints related to herbal medicine. The data extracted from the questionnaires were appropriately and meticulously tabulated, and data analysis was done by the Excel software.In this study, the formula below was used to calculate the frequency of plant use. Medicinal plants that are used as antianxiety and antidepressant drugs according to the ethnobotanical knowledge in Shahrekord include Fritillaria imperialis L., Ducrosia anethifolia L., Anchusa italyca Retz. (L.) DC., Dracocephalum multicaule, Stachys lavandulifolia, Thymus vulgaris, Tripleurospermum parviflorum L., Crataegus persica, Hypericum scabrum L., Valeriana officinalis, Centaurea cyanus, Rheum ribes L. and Melissa officinalis L are the most herbal plants effective on anxiety and depression on shahrekord ethno-botany.
Background Fatigue is a common compliant among patients who undergo coronary artery bypass graft (CABG) surgery. This may affect patients’ function in all aspects. A few studies have already assessed the influence of complementary therapies on minimizing fatigue. This study aimed to investigate the combined effect of vitamin C and omega-3 polyunsaturated fatty acids (n-3 PUFA) on fatigue following CABG surgery. Methods In this randomized, triple-blind placebo-controlled trial, 160 patients who already underwent CABG surgery were randomly assigned into an experimental or a control groups. Each group consisted of 80 patients. The experimental group was given both n-3 PUFA and vitamin C the day before surgery. They also received the same supplements in the first 5 days of operation. The control group received only placebo. Subjects in both groups responded to Multidimensional Fatigue Inventory (MFI-20) scale in the beginning, and at the end of the intervention as well as on the fifth day of the operation. Chi-square test and independent t-test were used for data analysis. Results The mean fatigue score in experimental and control groups came up to 62.01 ± 4.06 and 67.92 ± 4.95 (p<0.0001), respectively, which was greater than that of the values we had before intervention. The mean difference of fatigue score was 3.97 ± 3.49 and 9.56 ± 6.41 (p<0.0001) prior and following the intervention, correspondingly. Conclusion Combination of vitamin C and n-3 PUFA effectively reduces post-operative fatigue among patients who undergo CABG surgery.
Introduction: Coronary Artery Bypass Grafting (CABG) is a surgical procedure that aims to ease symptoms and reduce the risk of death in patients with coronary artery occlusion. In this surgery, healthy blood vessels from other parts of the body replace occluded coronary arteries. This surgery is done to improve blood supply to the heart. Because of its invasive nature, this procedure is associated with complications including postoperative bleeding. Methods: The study included 68 subjects in each group. The inclusion criteria were age of 40-80 years, serum creatinine under 1.5 mg/dl, platelet count above 100 thousand per microliter, hemoglobin above 8 g per deciliter, and normal PT and PTT. The patients underwent the procedure through the on-pump method. The study population included the patients undergoing CABG in Khorramabad Heart Hospital. The convenience, consecutive sampling method was applied, based on the inclusion criteria of the study. Results: The mean age of the patients treated with aspirin was 60.9 ± 11.05, and the mean age of the patients treated with aspirin plus clopidogrel was 60.48 ± 9.8 years. The mean FFP intake in the aspirin plus clopidogrel group during hospitalization was significantly higher than the mean in the aspirin group (PV= 0.0009). The mean cell pack intake in the aspirin plus clopidogrel group during hospitalization was higher than the mean in the aspirin group, but this difference was not statistically significant (PV=0.068) Discussion: The rate of postoperative bleeding in the clopidogrel plus aspirin group was higher than the rate in the aspirin group, but this difference was not significant (PV=0.067). The rate of Hb, HCT, and platelets in the aspirin plus clopidogrel group at discharge was higher than the rate in the aspirin group, which was due to excess bleeding in the aspirin plus clopidogrel group compared to the aspirin group. The rate of FFP intake in the aspirin plus clopidogrel group was significantly higher than the rate in the aspirin group, which was due to excess bleeding in the aspirin plus clopidogrel group (PV=0.0009).
B ackground, Sedatives are usually prescribed for people who are anxious and worried, and have developed depression. The use of these drugs in the short term can have benefits, but their use in the long term may develop drug addiction. Therefore, research attempts are being made to identify a natural and effective drug source to discover and ultimately produce effective sedative drugs. The aim, The aim of this study was to report plant species in Shahrekord, Iran, that are used as sedatives by collecting local people's information about their properties and methods of use. Methods, This study was conducted in 2017 using face-to-face interviews and a questionnaire distributed among 29 traditional therapists in the region under purpose. The data drawn from the questionnaires were meticulously and appropriately tabulated, and finally analyzed by the Excel software. Results, According to the ethnobotanical knowledge in the studied region, medicinal plants Melissa officinalis, Hypericum scabrum L, Dracocephalum multicaule , Anchusa italyca Retz, Valeriana officinalis, Origanum vulgare L , Kelussia odoratissima , Tanacetum polycephal , Hyssopus augustifolia , Alcea spp, Dianthum capillus-veneris, Lavandula angustifolia are used as herbal sedatives. Conclusion, These plants might be used as alternative or complementary remedies and might be used for preparation of new drugs.
Background: Identification of indigenous medicinal plants, including the gathering of information regarding the uses of these plants can help find out their traditional pharmacological activities and their benefits for the community’s healthcare system. In this study, an ethnobotanical investigation was conducted in Shahrekord city, southwest of Iran to indicate the ethnobotanical knowledge about analgesic medicinal plants in the region and the methods of using them. Materials and Methods: To this end, plant antioxidants and analgesic medicinal plants were identified. For this purpose, a questionnaire was used to obtain indigenous knowledge from traditional therapists in Shahrekord regarding pain relief using medicinal plants. This ethnobotanical study was conducted in 2018 with the participation of 29 traditional therapists of the region under purpose. Finally, the data drawn from the questionnaires were analyzed using the Excel software. The frequency of plants use was also calculated. Results: Our study showed that in Shahrekord, 23 species of medicinal plants are used to relieve pain. The highest frequency of use was obtained for Eugenia caryophylata (44%), followed by Alhagi maurorum (31%), Tribulus terrestris (27%), and angustifolia (24%). The Laminaceae family (7 species) was the most frequently used plant family for pain relief. The most frequently used plant organ to relieve the pain was flower (25%), followed by the stem (22%) and leaves (19%). Conclusion: Given the high importance of medicinal plants in Shahrekord, the results of this study and additional scientific investigations can help produce more effective and less harmful drugs from medicinal plants. [GMJ.2019;8:e1593]
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