An electrochemical acetylcholine sensor based on lichen-like nickel oxide nanostructure

Sattarahmady, N.; Heli, H.; Vais, R. Dehdari

doi:10.1016/j.bios.2013.04.001

Cited by 72 publications

(31 citation statements)

References 42 publications

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“…This diffusional behavior was also observed for other nickel-based electrodes [33,34,38,39], due to diffusion of proton in the bulk of nickel oxide [44].…”

Section: Characterization Of Nickel Nanowrinklessupporting

confidence: 67%

“…At ν500 mV s -, the values of Ep are linearly dependent on ln ν and the values of αs and ks were obtained as 0.52 and 2.96 s -1 , respectively. The value of ks for nickel nanowrinkles is higher than lichen-like nickel oxide nanostructure [38], nickel hydroxide nanopetals [39], nickel hydroxide nanoparticles [46] and flower-like nickel oxide nanostructure [47].…”

Section: Characterization Of Nickel Nanowrinklesmentioning

confidence: 88%

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Synthesis of nickel nanowrinkles and its application for the electrocatalytic oxidation and sensitive detection of hydrochlorothiazide

Heli

Pishahang

Amiri

et al. 2017

Microchemical Journal

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Nickel nanowrinkles were synthesized by a simple hydrothermal method in one step in the presence of fluoride ions in ethylene glycol. The nanowrinkles were then employed as the modifier of a carbon paste electrode. The kinetics of the charge transfer across the modified electrode/solution interface was studied and the modified electrode was employed to fabricate an amperometric sensor of hydrochlorothiazide. The mechanism and kinetics of the electrocatalytic oxidation of hydrochlorothiazide on the modified electrode surface were studied by cyclic voltammetry and chronoamperometry. An amperometric procedure was developed for determination of hydrochlorothiazide with a sensitivity of 13.50 mA mol-1 dm 3 cm-2 and a limit of detection of 21.2 mol dm-3. The method was used for the direct assay of hydrochlorothiazide in human serum samples and hydrochlorothiazide tablets. The sensor had the advantages of sensitivity (guaranteed by a Nafion layer on the sensor surface), high electrocatalytic activity and long-term stability toward hydrochlorothiazide.

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“…This diffusional behavior was also observed for other nickel-based electrodes [33,34,38,39], due to diffusion of proton in the bulk of nickel oxide [44].…”

Section: Characterization Of Nickel Nanowrinklessupporting

confidence: 67%

Section: Characterization Of Nickel Nanowrinklesmentioning

confidence: 88%

Synthesis of nickel nanowrinkles and its application for the electrocatalytic oxidation and sensitive detection of hydrochlorothiazide

Heli

Pishahang

Amiri

et al. 2017

Microchemical Journal

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“…Considering its high reactivity, the response of hPG/Pt to ACh was not surprising (du Toit and Di Lorenzo 2014a). Although the electrocatalytic oxidation of ACh on nanostructured electrodes has already been shown (Sattarahmady et al 2013), this is the first time that it is proven also for the case of porous gold.…”

mentioning

confidence: 80%

Towards timely Alzheimer diagnosis: A self-powered amperometric biosensor for the neurotransmitter acetylcholine

Moreira

Sale

Lorenzo

2017

Biosensors and Bioelectronics

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Serious brain disorders, such as the Alzheimer's Disease (AD), are associated with a marked drop in the levels of important neurotransmitters, such as acetylcholine (ACh). Real time monitoring of such biomarkers can therefore play a critical role in enhancing AD therapies by allowing timely diagnosis, verifications of treatment effectiveness, and developments of new medicines. In this study, we present the first acetylcholine/oxygen hybrid enzymatic fuel cell for the self-powered on site detection of ACh in plasma, which is based on the combination of an enzymatic anode with a Pt cathode. Firstly, an effective acetylcholinesterase immobilized electrode was developed and its electrochemical performance evaluated. Highly porous gold was used as the electrode material, and the enzyme was immobilized via a one step rapid and simple procedure that does not require the use of harsh chemicals or any electrode/enzyme pre-treatments. The resulting enzymatic electrode was subsequently used as the anode of a miniature flow-through membrane-less fuel cell and showed excellent response to varying concentrations of ACh. The peak power generated by the fuel cell was 4nW at a voltage of 260mV and with a current density of 9μAcm. The limit of detection of the fuel cell sensor was 10μM, with an average response time as short as 3min. These exciting results open new horizons for point-of-care Alzheimer diagnosis and provide an attractive potential alternative to established methods that require laborious and time-consuming sample treatments and expensive instruments.

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“…The use of nickel nanoparticles is widespread, e.g. in magnetic devices [1], as catalysts [2], in batteries [3] and electrochromatic devices [4], in fuel cells [5] and in sensors [6]. Numerous methods have been developed for the synthesis of nickel particles by researchers.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Investigation of Nickel Nanoparticles

Baumli¹,

Somlyai-Sipos²,

Czagány³

et al. 2019

World Congress on New Technologies

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The melting point is one of the most important thermodynamic properties of metallic materials. The melting point, that characterizes the bulk material is independent of the size in the microscopic range but will be size-dependent in the nano-range. The reason of this phenomenon is the high surface to volume ratio, thus the atoms situated on the surface play a greater role. One of the objectives of our research was to synthetize nickel nanoparticles (Ni NPs) using aqueous medium technology. The analysis of the produced particles was performed by X-ray diffraction (XRD) and Scanning electron microscopy (SEM). Furthermore, the main objective of our work was to determine the size dependence of the melting point of the produced nickel nanoparticles by differential scanning calorimetry (DSC).

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An electrochemical acetylcholine sensor based on lichen-like nickel oxide nanostructure

Cited by 72 publications

References 42 publications

Synthesis of nickel nanowrinkles and its application for the electrocatalytic oxidation and sensitive detection of hydrochlorothiazide

Synthesis of nickel nanowrinkles and its application for the electrocatalytic oxidation and sensitive detection of hydrochlorothiazide

Towards timely Alzheimer diagnosis: A self-powered amperometric biosensor for the neurotransmitter acetylcholine

Synthesis and Investigation of Nickel Nanoparticles

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