An efficient three-component, one-pot synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines in water

Li, Qiao-Yan; Zhang, Ge; Cheng, Tanyu; Li, Runtao

doi:10.1007/s11030-012-9376-z

Cited by 9 publications

(1 citation statement)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Highly substituted pyrimidines were also furnished by the catalysis of SDS or triethylamine. It was noteworthy that SDS requires an additional base to facilitate the reaction while triethylamine alone [211]. Triethylamine was also studied by Yan et al [212] for the condensation reaction of amidine hydrochlorides 349 and β-bromovinyl aldehydes 350 to produce pyrimidines 351 (Scheme 100) in good to excellent yields.…”

Section: Synthesis Of Pyrimidinesmentioning

confidence: 99%

Transition metal-free one-pot synthesis of nitrogen-containing heterocycles

et al. 2015

View full text Add to dashboard Cite

One-pot heterocyclic synthesis is an exciting research area as it can open routes for the development of otherwise complex transformations in organic synthesis. Heterocyclic compounds show wide spectrum of applications in medicinal chemistry, chemical biology, and materials science. These heterocycles can be generated very efficiently through highly economical and viable routes using one-pot synthesis. In particular, the metal-free one-pot synthetic protocols are highly fascinating due to several advantages for the industrial production of heterocyclic frameworks. This comprehensive review is devoted to the transition metal-free one-pot synthesis of nitrogen-containing heterocycles from the period 2010-2013.

show abstract

Section: Synthesis Of Pyrimidinesmentioning

confidence: 99%