An analysis of application of health informatics in Traditional Medicine: A review of four Traditional Medicine Systems

Ikram, Raja Rina Raja; Ghani, Mohd Khanapi Abd; Abdullah, Noraswaliza

doi:10.1016/j.ijmedinf.2015.05.007

Cited by 40 publications

(31 citation statements)

References 30 publications

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“…This shows that there is a huge informatics gap in the Traditional Malay Medicine field [9]. In addition, no literature was found for application of informatics in Traditional Malay Medicine [10].…”

Section: Introductionmentioning

confidence: 99%

A conceptual integrated health information systems framework in postnatal care for modern and traditional malay medicine

Ikram

Salahuddin

Naim

et al. 2020

IJEECS

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<span>This paper proposes an integrated health information systems framework for Traditional Malay Medicine (TMM) and modern medicine in the field of postnatal care. A qualitative study was conducted via healthcare experts in the field of modern medicine and Traditional Malay Medicine to assess the current situation and identify the research gap and point of isolation between both traditional and modern medicine field. A total of 26 healthcare practitioners whom represented five different set of healthcare organisations participated in this study. The healthcare practitioners consist of modern and traditional Malay medicine background with and without proper training. Results show that there is a gap in the current people, process and technology areas of the current framework. A novel conceptual framework, MyPostnatal, proposes the existence of a sufficiently generic, extensible in-formation model where new data sources can be integrated without major changes to the data scheme. Human and organization factors are also highlighted to stimulate the adoption towards electronic health records.</span>

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Section: Introductionmentioning

confidence: 99%

A conceptual integrated health information systems framework in postnatal care for modern and traditional malay medicine

Ikram

Salahuddin

Naim

et al. 2020

IJEECS

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“…Although vital research attention through a systematic literature review has been experienced over the past decades in the field, studies identifying themes as future research directions from existing research has been somehow limited. Ikram, Ghani and Abdullah (2015) conduced a systematic literature review to analyse the application of health informatics in the four traditional medicine systems -Chinese Medicine, Ayurveda, Traditional Arabic and Islamic Medicine and Traditional Malay Medicine. The study by Ikram et al (2015) utilised four databases (such as Ebsco Host, IEEE Explore, Proquest and Google scholar) finding the terms such as "Traditional Medicine", "informatics", "informatics infrastructure", "traditional Chinese medicine", "Ayurveda", "traditional Arabic and Islamic medicine", and "traditional Malay medicine".…”

Section: Introductionmentioning

confidence: 99%

“…Ikram, Ghani and Abdullah (2015) conduced a systematic literature review to analyse the application of health informatics in the four traditional medicine systems -Chinese Medicine, Ayurveda, Traditional Arabic and Islamic Medicine and Traditional Malay Medicine. The study by Ikram et al (2015) utilised four databases (such as Ebsco Host, IEEE Explore, Proquest and Google scholar) finding the terms such as "Traditional Medicine", "informatics", "informatics infrastructure", "traditional Chinese medicine", "Ayurveda", "traditional Arabic and Islamic medicine", and "traditional Malay medicine". Based on the combination of the search terms, the study explored the involvement of informatics as a modern medicine system.…”

Section: Introductionmentioning

confidence: 99%

Emerging Insights of Health Informatics Research: A Literature Analysis for Outlining New Themes

Miah

Shen

Lamp

et al. 2019

AJIS

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This paper presents a contemporary literature review to provide insights into the current health informatics literature. The objective of this study is to identify emerging directions of current health informatics research from the latest and existing studies in the health informatics domain. We analyse existing health informatics studies using a thematic analysis, so that justified sets of research agenda can be outlined on the basis of these findings. We selected articles that are published in the science direct online database. The selected 73 sample articles (published from 2014 to 2018 in premier health informatics journals) are considered as representative samples of health informatics studies. The analysis revealed ten topic areas and themes that would be of paramount importance for researchers and practitioners to follow. The findings provide an important foundational understanding for new health informatics studies.

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“…Drug-induced kidney injury has become a major cause of nephrotoxicity, which attracted high attentions of researchers. Chinese herbs, described as an artificial intelligence of healthcare practices with a long history of use, were largely unregulated without registration, monitor or verification ( Ikram et al, 2015 ; Stegelmeier et al, 2015 ). Chinese-herb nephropathy (CHN), a progressive renal interstitial fibrosis, was initially reported after intaking nephrotoxic components from Chinese herbs ( Debelle et al, 2003 ).…”

Section: Introductionmentioning

confidence: 99%

Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells

Wang

Feng

et al. 2017

Front. Pharmacol.

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Two natural compounds alisol A 24-acetate (24A) and alisol B 23-acetate (23B) are abundant in Rhizoma alismatis. In the present study, we evaluated the induction of 24A and 23B on apoptosis and possible nephrotoxicity of human renal proximal tubular (HK-2) cells by activating autophagy and also explored its regulation on PI3K/Akt/mTOR signaling pathway. Presently, Clusterin, Kim-1, and TFF-3 were considered to be new bioindicators of nephrotoxicity. Interestingly, the protein expression and mRNA levels of Clusterin, Kim-1 and TFF-3 could be significantly increased by 23B and 24A in vivo and in vitro. Furthermore, cell apoptosis could be triggered by 23B and 24A via significantly decreasing the protein expression and mRNA levels of Bcl-2 and Bcl-xl. Autophagy of HK-2 cells could be induced by both 23B and 24A via significantly enhancing the ratio of LC3II/LC3I, the protein expression of Beclin-1 as well as the mRNA levels of LC3 and Beclin-1. Meanwhile, PI3K/Akt/mTOR signaling pathway could be inhibited by these two compounds. An autophagy inhibitor, 3-methyladenine, could partially reverse cell viability and conversely change the ratio of LC3II/LC3I and the protein expression of Bcl-2 and Kim-1. Thus this study helped to understand that 23B and 24A induced autophagy resulted in apoptosis and nephrotoxicity through inhibiting PI3K/Akt/mTOR signaling pathway, facilitating further studies for nephrotoxicity induced by these two compounds and could be beneficial for safe use of Rhizoma alismatis in clinic.

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An analysis of application of health informatics in Traditional Medicine: A review of four Traditional Medicine Systems

Cited by 40 publications

References 30 publications

A conceptual integrated health information systems framework in postnatal care for modern and traditional malay medicine

A conceptual integrated health information systems framework in postnatal care for modern and traditional malay medicine

Emerging Insights of Health Informatics Research: A Literature Analysis for Outlining New Themes

Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells

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