&amp;lt;i&amp;gt;GHRH/Hae&amp;lt;/i&amp;gt;III gene polymorphism and its associations with milk production traits in Polish Black-and-White cattle (short communication)

Dybus, Andrzej; Grzesiak, Wilhelm

doi:10.5194/aab-49-434-2006

Cited by 14 publications

(17 citation statements)

References 19 publications

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“…According to these authors, the rare AA genotype was significantly associated with the discussed traits (P ≤ 0.01). DYBUS and GRZESIAK (2006) also found that cows with one or two GHRH A alleles might produce milk of a higher fat percentage, although this was not statistically signifi cant. However, a low number of the individuals with the AA genotype strongly limits the conclusions.…”

Section: : a Part Of The Fluorogram Of Intron 2 Of Bovine Ghrh Gene mentioning

confidence: 99%

Effect of growth hormone-releasing hormone gene polymorphism (GHRH/HaeIII) on milk performance in polish holstein-friesian cows

Szewczuk¹,

Zych²,

Chaberski³

2014

Acta Univ. Agric. Silvic. Mendelianae Brun.

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SZEWCZUK, M., ZYCH, S., CHABERSKI, R.: Eff ect of growth hormone-releasing hormone gene polymorphism (GHRH/HaeIII) on milk performance in polish holstein-friesian cows. Acta univ. agric. et silvic. Mendel. Brun., 2008, LVI, No. 4, pp. 177-182 The objective of this study was to evaluate the relationship between the polymorphism within GHRH gene (GHRH/HaeIII) and milk production traits for Polish Holstein-Friesian using PCR-RFLP technique for genotyping. The molecular background of this mutation was defi ned as the A→C transversion at the intron 2. A total of 220 cows were examined. The following frequencies were established: 0.0227 for genotype AA, 0.3227 for AB, and 0.6546 for BB; 0.1841 for the allele GHRH A and 0.8159 for GHRH B . A highly signifi cant association was found between the GHRH/HaeIII polymorphism and milk performance. The BB-genotype cows were characterised by a higher fat yield and percentage (P ≤ 0.01). dairy cattle, milk production traits, PCR-RFLP, somatoliberin Molecular genetics has created new means of animal improvement. A range of genetic markers associated with milk performance have been discovered.

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Section: : a Part Of The Fluorogram Of Intron 2 Of Bovine Ghrh Gene mentioning

confidence: 99%

Effect of growth hormone-releasing hormone gene polymorphism (GHRH/HaeIII) on milk performance in polish holstein-friesian cows

Szewczuk¹,

Zych²,

Chaberski³

2014

Acta Univ. Agric. Silvic. Mendelianae Brun.

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“…Contrastly, genotype frequencies of this gene were mostly different for Limousin GG (0.667), AA (0.238) and AG (0.095), Simmental AG (0.529), GG (0.471) and AA (0.000), Pesisir AA (0.604), GG (0.375) and AG (0.021) stated as polymorphic evidences. Dybus & Grzesiak (2006) in their study on the evaluation of the diversity of GHRH gene with milk production in Poland dairy cattle. From that study identified three genotypes and two alleles, by the genotypes of AA (0.0545), AB (0.3133) and BB (0.6322); as well as by the alleles of A (0.2111) and B (0.7889).…”

Section: Genotype and Allele Frequencies Of The Ghrh Genementioning

confidence: 99%

GHRH|HaeIII Gene Polymorphism in Dairy and Beef Cattle at National Livestock Breeding Centers

Rini¹,

Sumantri²,

Anggraini³

2013

Med Pet

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ABSTRACT), kecuali pada sapi FH di BIB Lembang, sapi Brahman, dan Angus di BET Cipelang. Nilai heterozigositas tertinggi adalah 0,471 untuk sapi FH pejantan di BIB Lembang, sebaliknya, nilai terendah adalah 0,344 untuk sapi FH pejantan di BBIB Singosari. Nilai heterozigositas sapi FH lebih rendah daripada sapi Simmental dan Limousin. Gen GHRH pada sapi FH dan sapi pedaging menunjukkan polimorfik, kecuali pada sapi Brahman yang hanya memiliki alel B.

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“…Changes in the functional regions of GHR can affect its binding capacity and signalling pathway, and therefore alter the activity of GH in the target tissues (Olenski et al, 2010). Several polymorphisms of bovine GHR were described by Dybus & Grzesiak (2006) and Kmiec et al (2007). The growth promoting and metabolic actions of the GH are generally mediated by insulin-like growth factor I (IGF-I), which is a 70 amino-acid, single-chain polypeptide produced in the liver in response to GH.…”

Section: Introductionmentioning

confidence: 99%

Genetic variability of bovine GHR, IGF-1 and IGFBP-3 genes in Indian cattle and buffalo

Ramesha¹,

Rao²,

Basavaraju³

et al. 2016

SA J. An. Sci.

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The identification of genetic polymorphisms in the genes that play a crucial role in regulatiing growth and development of livestock enables us to evaluate the biological similarities and to acquire a better perspective of quantitative traits. The present study was undertaken to characterize genetic variability in the bovine growth hormone receptor (GHR), insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3) genes among Bos indicus (Malnad Gidda, Khillar), Bos taurus (Holstein Friesian, Jersey) cattle and Asian water buffalo Bubalus bubalis (Murrah, Surti) using polymerase chain reactionsingle strand conformation polymorphism (PCR-SSCP) analysis. These polymorphisms were confirmed by direct sequencing. The comparative gene sequence analysis in cattle and buffalo breeds revealed 18 single nucleotide polymorphisms (SNPs) across different loci. Eight SNPs were detected in the bovine growth hormone receptor (GHR) gene, of which four were found in the promoter region and four in the exon 4 region. In the IGF-1 gene, two SNPs were observed in the 5ˈUTR, three SNPs in the intron 3 region and two SNPs in the coding region of exon 4. Three SNPs were detected in the exon 2 region of the bovine IGFBP-3 gene. The frequency of rare alleles observed in the present study ranged from 0.04 to 0.16. The present results revealed high levels of genetic variability in the GHR, IGF-1 and IGFBP-3 genes in cattle and buffalo reared in India.

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<i>GHRH/Hae</i>III gene polymorphism and its associations with milk production traits in Polish Black-and-White cattle (short communication)

Cited by 14 publications

References 19 publications

Effect of growth hormone-releasing hormone gene polymorphism (GHRH/HaeIII) on milk performance in polish holstein-friesian cows

Effect of growth hormone-releasing hormone gene polymorphism (GHRH/HaeIII) on milk performance in polish holstein-friesian cows

GHRH|HaeIII Gene Polymorphism in Dairy and Beef Cattle at National Livestock Breeding Centers

Genetic variability of bovine GHR, IGF-1 and IGFBP-3 genes in Indian cattle and buffalo

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