“…Although the prevalence is therefore highest in under-resourced developing countries with the lowest levels of sanitation, occurrence in developed countries is documented in association with modern travel, high rates of emigration and the existence of high risk groups, such as institutionalised patients and homosexuals [1,16,18]. While the clinicopathological spectrum, morbidity and mortality of invasive intestinal amoebiasis are well recorded in medical literature [6,13,18], clinicopathological reports on isolated amoebic appendicitis (IAA), regarded as a rare intestinal manifestation of invasive amoebiasis globally, are confined mainly to single case reports [2,3,12,17,20,24,25,32]. Although amoebic appendicitis may share the spectrum of complications and morbidity and mortality trends associated with invasive amoebic colitis, some authors have documented excellent outcome in IAA [2,24,25].…”