Amebic Acute Appendicitis: Systematic Review of 174 Cases

Otan, Emrah; Akbulut, Sami; Kayaalp, Cüneyt

doi:10.1007/s00268-013-2079-5

Cited by 30 publications

(27 citation statements)

References 49 publications

(83 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One previous systematic review showed that preoperative diagnosis was established in only 3.0% of the patients (12). On the other hand, there are no epidemiological studies that used highly sensitive methods to detect E.…”

Section: Discussionmentioning

confidence: 99%

“…Two review articles reported the clinical features of amoebic appendicitis (11, 12). The oversight of E.…”

Section: Introductionmentioning

confidence: 99%

“…histolytica infection sometimes results in serious complications after appendectomy. It was reported that amoebic appendicitis presents a high rate of perforated appendicitis at surgery (26.1%) and a high rate of postoperative complications (25.4%) (12, 13). Also, several case reports indicated that the diagnosis of E.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Underestimated Amoebic Appendicitis among HIV-1-Infected Individuals in Japan

et al. 2017

View full text Add to dashboard Cite

Entamoeba histolytica is not a common causative agent of acute appendicitis. However, amoebic appendicitis can sometimes be severe and life threatening, mainly due to a lack of awareness. Also, its frequency, clinical features, and pathogenesis remain unclear. The study subjects were HIV-1-infected individuals who presented with acute appendicitis and later underwent appendectomy at our hospital between 1996 and 2014. Formalin-fixed paraffin-embedded preserved appendix specimens were reexamined by periodic acid-Schiff (PAS) staining and PCR to identify undiagnosed amoebic appendicitis. Appendectomies were performed in 57 patients with acute appendicitis. The seroprevalence of E. histolytica was 33% (14/43) from the available stored sera. Based on the medical records, only 3 cases were clinically diagnosed as amoebic appendicitis, including 2 diagnosed at the time of appendectomy and 1 case diagnosed by rereview of the appendix after the development of postoperative complications. Retrospective analyses using PAS staining and PCR identified 3 and 3 more cases, respectively. Thus, E. histolytica infection was confirmed in 9 cases (15.8%) in the present study. Apart from a significantly higher leukocyte count in E. histolytica-positive patients than in negative patients (median, 13,760 versus 10,385 cells/μl, respectively, P = 0.02), there were no other differences in the clinical features of the PCR-positive and -negative groups. In conclusion, E. histolytica infection was confirmed in 9 (15.8%) of the appendicitis cases. However, only 3, including one diagnosed after intestinal perforation, were diagnosed before the present analyses. These results strongly suggest there is frequently a failure to detect trophozoites in routine examination, resulting in an underestimation of the incidence of amoebic appendicitis.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Two review articles reported the clinical features of amoebic appendicitis (11, 12). The oversight of E.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Underestimated Amoebic Appendicitis among HIV-1-Infected Individuals in Japan

et al. 2017

View full text Add to dashboard Cite

show abstract

“…This was not the issue in our case. Turkish authors obtained a total of 174 cases of amebic appendicitis using the PubMed and MEDLINE databases [7]. The mean age of the patients was 23.5 years (range 2 months-83 years).…”

Section: Discussionmentioning

confidence: 99%

Amebiasis Presenting as Acute Appendicitis: Case Report

Onuigbo¹

2018

OARA

View full text Add to dashboard Cite

“…Clinically, there may be a clinical course that varies from mild colitis and hemorrhagic dysentery to toxic megacolon, colon perforation and peritonitis. Perforation and peritonitis emerging as a result of fulminant colitis and intestinal necrosis are observed in 0.5% of patients and the mortality rate of these patients is above 40% (4). In a series of amebic appendicitis reported from Japan, postoperative intraabdominal severe complication rate reported as 37%, and the mortality rate reported as 25% (2).…”

Section: Amebiasis Is a Parasitic Infection Caused By Amoeba Called Ementioning

confidence: 99%