Alterações na audiometria de tronco encefálico em mulheres adultas com hipotireoidismo subclínico

Abstract

A correlação entre perda auditiva e distúrbios adquiridos da glândula tireóide tem sido tema de interesse há muito tempo na Medicina. Diversos trabalhos foram dedicados à investigação audiológica de pacientes com hipotireoidismo, mas poucos autores abordaram a forma subclínica desta doença utilizando a audiometria de tronco encefálico (ABR). Objetivo: Avaliar se ocorrem ou não alterações na ABR em mulheres normoacúsicas com hipotireoidismo subclínico não tratado quando comparadas a mulheres sem doença endócrina. Desenho do Estudo: Prospectivo clínico. Material e Método: Uma série de 16 pacientes foi analisada com ABR e seus resultados foram relacionados aos do grupo-controle análogo em sexo e idade. Resultados: Houve diferença significativa (p<0,05) nas médias das latências absolutas das ondas III (p=0,039) e V (p=0,006) e dos intervalos interpicos I-III (p=0,017), III-V (p=0,044) e I-V (p=0,002) entre os dois grupos, mostrando que as medidas destas latências foram significativamente maiores no grupo do hipotireoidismo. Conclusão: Na condição de hipotireoidismo subclínico, antes mesmo de haver qualquer anormalidade nos limiares psicoacústicos, já poderá ser observado comprometimento na condução nervosa ao longo das vias auditivas no tronco encefálico, como demonstrado pela avaliação com ABR. Lília ORIGINAL ARTICLE ARTIGO ORIGINAL «««« ««««The association between hearing loss and acquired disorders of the thyroid gland have been an interesting topic for a long time in Medicine. Several researches were based on audiological studies of hypothyroid patients but few authors conducted studies of the sub clinical form of the disease using auditory brainstem response (ABR). Aim: To evaluate whether there are or are not changes on the ABR study of normal hearing adult females with sub clinical hypothyroidism without treatment compared to a group of women without endocrine disease. Study Design: Clinical prospective. Material and Method: A group of 16 patients was analyzed with ABR test and its results were co-related to age-and sex-matches control group. Results: There was a significative difference (p<0,05) between absolute latencies averages of the waves III(p=0,039) and V(p=0,006) and interpeak latencies I-III(p=0,017), III-V(p=0,044) and I-V(p=0,002) on both groups, showing that measures of these latency periods were significantly larger on the hypothyroid patients. Conclusion: In sub clinical hypothyroidism conditions, even before presentation abnormalities in subjective pure-tone threshold, we can have nervous conduction involvement on the brainstem auditory pathways as given evidences by assessment of ABR.Rev Bras Otorrinolaringol. V.69, n.4, 542-7, jul./ago. 2003

Hearing levels in patients with subclinical hypothyroidism

“…Diğer taraftan Figueiredo ve ark. [18] 23 subklinik hipotiroidili hasta üzerinde yaptıkları bir çalışmada BAEPs testinde III ve V dalgada gecikme ve I-III, III-V ve I-V dalgalar arası anlamlı değişiklik izlendiğini belirtmişlerdir.…”

Assessment of Audiologic Evaluation in Patients with Acquired Hypothyroidism

“…And one case also had deterioration in hearing. Further it was observed that the thyroxine treatment influences the hearing maximally at 1000 Hz, the frequency at which 31 ears had a significant gain of 10 db or more There are diverse views regarding improvement in hearing in hypothyroid patients with thyroxine treatment [12]. Although it was not the endeavour of this study to analyse the vestibular changes in goitrous hypothyroid-ism, the authors would like to highlight that almost 39% cases had a history of vertigo, out of which 26 patients had an subjective improvement after levothyroxine therapy at the end of 6 months.…”

Congenital Hypothyroidism and the Deleterious Effects on Auditory Function and Language Skills: A Narrative Review

“…This data is significantly worrying when thinking about the harm that the reduction or absence of action of TH in the crucial periods of neurological development and maturation can bring. The central nervous system is one of the most affected ( 51 ), and it can alter the processing of the acoustic signal up to the cortex, causing difficulties in auditory skills ( 52 ) that will result in problems with behavioral, language, and social difficulties.…”