Alterações dermatológicas nos pacientes em hemodiálise e em transplantados

Abstract

Recently, the world is facing an escalate in the incidence of chronic kidney disease (CKD). Databases containing information about patients in end stage renal disease (ESRD), especially in the United States, were the sources of initial information about it. Brazil has the third largest population on dialysis in the world, and there are about 680 dialysis centers, spread across all units of the federation in the present, providing treatment to an estimated population of almost 90,000 patients. Cutaneous involvement in the chronic renal failure is characterized by a number of manifestations, which may be related to three processes: the primary renal disease, the uremic state, or the therapeutic measures used in their handling. The skin changes in these two classes of patients, dialysis and transplant recipients, have been the subject of several studies. n recent years, however, great progress has been achieved in these two therapeutic modalities, which may have changed not only the type of the dermatologic disorders associated with these two conditions, but also their intensity or frequency. This article aims to yield an update as to the topic skin diseases in hemodialysis and kidney transplant patients.

Dermatosis in dialytic chronic kidney failure

“…A histopathological exam with staining by Masson’s trichrome demonstrated transepidermal elimination of collagen ( Figure 1 D ) and orcein staining revealed preservation of elastic fibers. The diagnosis of acquired perforating dermatosis was based on clinical, histopathological, and onset findings at 38 years of age 4 , 5 .…”