Aloe vera-based antibacterial porous sponges for wound dressing applications

Tamahkar, Emel; Özkahraman, Bengi; Özbaş, Zehra; İzbudak, Burçin; Yarimcan, Filiz; Boran, Filiz; Bal‐Öztürk, Ayça

doi:10.1007/s10934-020-01029-1

Cited by 21 publications

(8 citation statements)

References 40 publications

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“…In vitro cytotoxicity evaluation of tissue adhesives was performed using the “indirect MTT assay” according to the standard test method. 30–32 Human corneal fibroblast cell lines (HCFs) were used. The passage number of cells was 3.…”

Section: Methodsmentioning

confidence: 99%

Photocurable silk fibroin-based tissue sealants with enhanced adhesive properties for the treatment of corneal perforations

et al. 2022

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Section: Methodsmentioning

confidence: 99%

Photocurable silk fibroin-based tissue sealants with enhanced adhesive properties for the treatment of corneal perforations

et al. 2022

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“…The swelling behaviors of the hydrogel films were determined by the gravimetric method following the protocol 40 . The dry hydrogel films ( W Dried ) were weighed (~0.25 g) and placed in PBS at 37°C for 24 h. Then, the swollen hydrogel films were taken out and weighed ( W Swollen ) after the excess water was removed by filter paper.…”

Section: Methodsmentioning

confidence: 99%

Boric acid‐impregnated silk fibroin/gelatin/hyaluronic acid‐based films for improving the wound healing process

Özen

Özbaş

İzbudak

et al. 2021

J of Applied Polymer Sci

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Recently, with the progression in wound dressings, the importance of the biocompatible material with enhanced features for potential applications in the biomedical field has been more developed. Current strategies focus on the acceleration of the wound healing by systematically designed dressing materials. In this study, biocompatible hydrogel films with the combination of silk fibroin, hyaluronic acid and gelatin biopolymers were fabricated. To gain the enhanced wound healing behavior of wound dressings, boric acid (BA) was formulated in various ratios. The prepared hydrogel films were characterized in terms of FTIR, TGA, DSC, and SEM analysis. Following to the swelling and mechanical tests, in vitro biocompatibility and wound healing tests were performed against L929 fibroblast cell line. Results suggest that the presence of 1% (wt/vol) BA in the formulation of silk fibroin/gelatin/hyaluronic acid based hydrogel films is the key in providing such an enhanced mechanical and wound healing feature and may offer an alternative approach for wound healing treatment.

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“…Typically, this material causes antibacterial activity by interfering with the adhesion of bacteria to the surface, changing the nature of cell membranes or blocking the penetration of glucose into bacterial cells. [95,96] In many of the previous studies, chitosan, [49,97] keratin, [46,98] honey, [99,100] pectin, [101,102] and aloe vera [103,104] have been used in wound healing applications.…”

Section: Solvent Castingmentioning

confidence: 99%

An Overview on the Recent Advances in the Treatment of Infected Wounds: Antibacterial Wound Dressings

Mirhaj

Labbaf

Tavakoli

et al. 2022

Macromolecular Bioscience

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A wound can be surgical cuts from an operation or due to accident and trauma. The infected wound, as a result of bacteria growth within the damaged skin, interrupts the natural wound healing process and significantly impacts the quality of life. Wound dressing is an important segment of the skincare industry with its economic burden estimated at $ 20.4 billion (in 2021) in the global market. The results of recent clinical trials suggest that the use of modern dressings can be the easiest, most accessible, and most cost‐effective way to treat chronic wounds and, hence, holds significant promise. With the sheer number of dressings in the market, the selection of correct dressing is confusing for clinicians and healthcare workers. The aim of this research is to review widely used types of antibacterial wound dressings, as well as emerging products, for their efficiency and mode of action. In this review, introducing antibiotics and antibacterial nanoparticles as two important and clinically widely used categories of antibacterial agents is focused. The perspectives and challenges for paving the way for future research in this field are also discussed.

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Aloe vera-based antibacterial porous sponges for wound dressing applications

Cited by 21 publications

References 40 publications

Photocurable silk fibroin-based tissue sealants with enhanced adhesive properties for the treatment of corneal perforations

Photocurable silk fibroin-based tissue sealants with enhanced adhesive properties for the treatment of corneal perforations

Boric acid‐impregnated silk fibroin/gelatin/hyaluronic acid‐based films for improving the wound healing process

An Overview on the Recent Advances in the Treatment of Infected Wounds: Antibacterial Wound Dressings

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