Allium Sativum Essential Oil (Aseo); Effect of Supplementation on Serum Triglycerides, Total Cholesterol, Hdlc, LDLC and Blood Cell Counts in Albino Rats

Abstract

ABSTRACT… Objectives:To determine the effects of Allium sativum essential oil (ASEO) phytotherapy on serum triglycerides, total cholesterol, HDLc, LDLc and blood cell counts in albino rat model. Study design: Experimental study. Setting and Duration: Animal House, Sindh Agriculture University and Isra University Hyderabad from May 2014 to January 2015. Materials and Methods: 60 albino rats were divided into four groups. Controls were given Placebo. Experimental rat groups were given ASEO 100 mg/kg, 200 mg/kg and 300 mg/kg orally for 30 days. Cardiac puncture was performed for blood sampling. Research variables were analyzed on Statistix 10.0 (USA). Results: Blood lipids showed significant reduction in various blood lipid fractions. Serum LDLc exhibited with a concomitant rise in serum HDLc (p =0.0001) in high ASEO treated rats. Red blood cells, white blood cells and platelet showed significant improvement ASEO fed rats (p=0.001). Conclusion: Allium sativum essential oil (ASEO) phytotherapy showed a rise in HDLc and a reduction in LDLc, triglycerides and total cholesterol with improvement in red blood cell counts. Key words:Allium sativum essential oil Blood lipids LDLc HDLc Blood cell counts Rats. Article Citation: Irshad F, Mawani H, Naz S. Allium sativum essential oil (ASEO); effect of supplementation on serum triglycerides, total cholesterol, HDLC, LDLC and blood cell counts in albino rats. Professional Med J 2017;24(4):612-616.

Propriedades funcionais do açafrão, cebola e alho no combate à dislipidemia, uma revisão integrativa

“…-Redução dos níveis de CT, TGs, LDL-c e aumento HDL-c (p<0,05). IRSHAD; MAWANI; NAZ, 2017. YANG et al, 2018.…”