Allergic rhinitis in children

Barr, James; Al-Reefy, Hiba; Fox, Adam; Hopkins, Claire

doi:10.1136/bmj.g4153

Cited by 29 publications

(19 citation statements)

References 59 publications

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“…Allergic rhinitis may be classified as intermittent or persistent in accordance with symptom frequency. 102 In adults, it was suggested that obesity predisposes to AR in an inflammatory way by modifying adipocytokines profile, leptin, and adiponectin and by stimulating the synthesis of proinflammatory cytokines and acute-phase proteins. 103 Saadeh et al examined a large French pediatric population finding that high BMI (defined as obesity or OW) correlated positively with AR incidence.…”

Section: Allergic Rhinitismentioning

confidence: 99%

The Association Between ENT Diseases and Obesity in Pediatric Population: A Systemic Review of Current Knowledge

2019

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Obesity in pediatric population is an important global problem. The prevalence of obesity in children is dramatically rising. According to World Health Organization, about 41 million children under the age of 5 years are obese or overweight worldwide. Overweight and obesity are well-known risk factors for a number of health disorders. Diseases commonly observed in this group of patients are metabolic disorders, type 2 diabetes mellitus, cardiovascular diseases, fatty liver disease, musculoskeletal problems, and many others. The main aim of this study was to present the current knowledge of the association between childhood obesity and common otorhinolaryngological disorders. It is suggested that obese children are more prone to suffer from otorhinolaryngological illnesses than the lean ones. Obesity may predispose to otorhinolaryngological diseases in various ways. It strongly interferes with the immune system (increases serum levels of interleukin 6, tumor necrosis factor, C-reactive protein, and leptin and reduces adiponectin concentration) affecting organs of the upper respiratory tract. Additionally, obesity induces mechanical disorders in the upper airways. According to our review, obesity predisposes to otitis media with effusion, acute otitis media, recurrent otitis media, obstructive sleep apnea, sensorineural hearing loss, adenotonsillar hypertrophy, and post-/perioperative complications after adenotonsillectomy. Obesity in children significantly correlates with both obstructive sleep apnea (OSA) and asthma and constitutes a significant component of ''OSA, obesity, asthma'' triad.

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Section: Allergic Rhinitismentioning

confidence: 99%

The Association Between ENT Diseases and Obesity in Pediatric Population: A Systemic Review of Current Knowledge

2019

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“…) and rhinitis (Barr et al . ). The natural causes of allergy are complex and not clearly understood.…”

Section: Introductionmentioning

confidence: 97%

“…Over the past decades, the prevalence of allergic diseases has grown rapidly, affecting more than 20% of the population in industrial countries (Wu et al 2011). This increase in prevalence has been associated with a large percentage of allergy-related comorbidity, such as asthma (Kim et al 2014) and rhinitis (Barr et al 2014). The natural causes of allergy are complex and not clearly understood.…”

Section: Introductionmentioning

confidence: 99%

Oral application of lactic acid bacteria following treatment with antibiotics inhibits allergic airway inflammation

Zhang

Wang

et al. 2015

J Appl Microbiol

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“…With an increasing prevalence over the last few decades shown by previous studies, AR, not surprisingly, has become a well-recognized allergic disease in children. 1 , 2 Detection of aeroallergens sensitization is of great importance in diagnosing AR and optimizing the care of AR patients and management of this disorder. 2 , 3 …”

Section: Introductionmentioning

confidence: 99%

A 10-year retrospective study of alterative aeroallergens sensitization spectrum in urban children with allergic rhinitis

Yang

Cai

et al. 2018

TCRM

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ObjectiveTo investigate the alterative spectrum and trends of aeroallergens sensitization in children with allergic rhinitis (AR) in Guangzhou, China in the past 10 years.Participants and methodsIn this retrospective study, 4,111 children with complaints of nasal hyper-reactivity who visited the Pediatric Department and/or Otolaryngology Department from January 2007 to November 2016 were enrolled. Serum specific immunoglobulin E was measured and positive detection was made in 3,328 patients, who were, therefore, diagnosed with AR. Positive rates and trends of different aeroallergens sensitization were assessed. The tendency of positive rates changing over the years, and the difference and trends in positive rate of aeroallergen sensitization that occurred in subgroups of gender, age, and season were determined and analyzed with logistic regression.ResultsThe percentage of detected common aeroallergens in AR children was (from high to low) 81.07%, 34.44%, 14.72%, 11.81%, 6.04%, and 3.70% for house dust mites (HDMs), cat–dog dander, cockroach, mold mixture, tree pollen mixture, and herb pollen mixture, respectively. An ascending trend of aeroallergens sensitization or AR (odds ratio [OR] =1.116, 95% CI: 1.086–1.146) was found. Interestingly, an increasing trend of cat–dog dander and mold sensitization was found in AR children (OR =1.164, 95% CI: 1.133–1.196; OR =1.169, 95% CI: 1.120–1.223) in this retrospective study, while HDMs sensitization held a steady trend (OR =0.983, 95% CI: 0.961–1.007).ConclusionIn the increasing trend of aeroallergens sensitization or AR, HDMs sensitization still held the majority. But emphasis should be made on pet allergy for young children with AR in the context of ascending trend of sensitization to cat–dog dander.

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Allergic rhinitis in children

Cited by 29 publications

References 59 publications

The Association Between ENT Diseases and Obesity in Pediatric Population: A Systemic Review of Current Knowledge

The Association Between ENT Diseases and Obesity in Pediatric Population: A Systemic Review of Current Knowledge

Oral application of lactic acid bacteria following treatment with antibiotics inhibits allergic airway inflammation

A 10-year retrospective study of alterative aeroallergens sensitization spectrum in urban children with allergic rhinitis

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