Allergic contact dermatitis caused by acrylates in nail cosmetic products: Case reports and review of the literatures

Lin, Yi; Tsai, Shih‐Wei; Yang, Ching Wen; Tseng, Yu Hsian; Chu, Chia-Yu

doi:10.1016/j.dsi.2018.05.001

Cited by 6 publications

(5 citation statements)

References 14 publications

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“…The oral symptoms include subjective sensations like burning or soreness in the mouth, loss of taste, numbness, mucous membrane inflammation, vesiculations, erosions, lichenoid reaction confined to the area in contact with dental materials [ 21 ]. During last decades, (meth)acrylate allergy has undergone an occupational shift from dentistry toward beauty industry, and this change seems to be constantly trending upwards in many countries [ 22 ]. The most important sources of sensitisation are eyelash, hair extensions and primarily artificial nails [ 18 , 23 ].…”

Section: Sources Of Exposurementioning

confidence: 99%

Acrylates as a significant causes of allergic contact dermatitis – new sources of exposure

Kucharczyk

Słowik-Rylska

Cyran-Stemplewska³

et al. 2021

pdia

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Acrylate monomers have a wide range of applications. Since the 1950s, many reports of occupational origin allergic contact dermatitis due to (meth)acrylate monomers have been published. During last decades, (meth)acrylate allergy has undergone an occupational shift from dentistry toward beauty industry and medical devices. The aim of the study was to conduct a literature review on acrylates as a cause of allergic contact dermatitis, current sources of exposure as well as identification of professional groups with an increased risk of this allergy and methods of effective prevention. Database review: Medline search (PubMed), Wiley Online Library and Web of Science base in years 1956–2019 using the following keywords: acrylates, manicurists, dentists, dental technicians, medical devices, occupational exposure, and allergic contact dermatitis. 204 346 articles containing the term ‘acrylates‘ have been found. They include 2 042 articles with the word ‘manicurists’, 169 919 – ‘dentists’, 218 236 – ‘dental technicians’, 2 427 418 – ‘medical devices’. Fifty-nine articles were chosen based on analysis of abstracts and full texts. In the past allergy to acrylates was mainly of occupational origin and dental technicians were the most often affected professional group. Since the long-lasting manicure has become popular, this problem concerns both manicurists and their customers. Moreover, the new significant trend is non-occupational allergic contact dermatitis caused by medical devices especially dedicated to diabetes patients.

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Section: Sources Of Exposurementioning

confidence: 99%

Acrylates as a significant causes of allergic contact dermatitis – new sources of exposure

Kucharczyk

Słowik-Rylska

Cyran-Stemplewska³

et al. 2021

pdia

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“…In recent decades, the occurrence of allergy to (meth)acrylates has shifted from dentistry to the beauty industry, where the application of acrylates has become very frequent [26]. Concerning acrylates in cosmetics, the most important sources of sensitization are artificial eyelashes, hair extensions, and artificial nails [27,28].…”

Section: Acrylates In Cosmetics and Medicinementioning

confidence: 99%

Unwanted Skin Reactions to Acrylates – an Update

Lugović-Mihić,

Filija,

Varga

et al. 2024

Preprint

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Acrylates and methacrylates are widely used, especially in the dental industry, but can cause adverse skin reactions. These compounds, including 2-hydroxyethyl methacrylate, triethylene glycol dimethacrylate, and bisphenol A-glycidyl methacrylate, are strong contact irritants or allergens. Found in dental prostheses, composite resins, dentin bonding materials, and glass ionomers, they pose a higher risk of exposure for dental personnel. Clinically, acrylate allergies manifest as facial rashes, eczema with cracked skin on fingers (pulpitis), nail dystrophy, and periungual dermatitis. Recently, the highest frequency of allergic reactions to acrylates has shifted from dentistry to the beauty industry due to increased use in artificial nails, eyelashes, and hair extensions. This has led to greater sensitization. Acrylates are also used in medical applications, such as bone cement for orthopedic endoprostheses, soft contact lenses, hearing aids, histological preparations, and wound dressings, which can also cause allergic reactions. Severe dermatitis from surgical glue containing acrylates has been documented, and diabetic medical devices are potential sources of allergic contact dermatitis. Given the extensive use and prolonged skin contact of products containing acrylates and methacrylates, this review aims to present current knowledge and literature on reactions to these compounds across different industries.

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“…They are formed by the polymerisation of small monomers that are chemically linked and form polymer molecular chains. It is a known fact that monomers are strong irritants and sensitisers, while polymers are significantly less active or safe [1,2].…”

Section: Introductionmentioning

confidence: 99%

Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients

Gospodinova,

Angelova,

Gergovska

et al. 2023

Journal of Biomedical and Clinical Research

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Summary The study aimеd to investigate the association between the professional environment and hypersensitivity reactions to various contact allergens, features of the clinical course, and types of allergic contact dermatitis (ACD) in 34 manicurists and ten service users. The analysis was based on the data on length of professional experience, localisation of rashes, clinical diagnoses and allergens, and the cause of positive reactions in epicutaneous testing. Pathological skin changes most often affected the upper limbs (hands, palms, fingers). As a diagnosis, the frequency of ACD was the highest – 79.4%, followed by that of dyshidrotic eczema (DE) – 17.6%, which also determines the highest percentage of dermatitis on the upper limbs (97%). Of the patients, 47.1% had a history of the disease for up to one year. For manicurists, the results of patch tests with the specialised MH-1000 series showed the highest frequency of positive reactions to 2-Hydroxyethyl methacrylate (2-HEMA) and 2-Hydroxypropyl methacrylate (2-HPMA) – 88.88% each, Ethylene glycol dimethacrylate (EGDMA) – 83.33% and 2-Hydroxyethyl acrylate (2-HEA) – 61.11%. After combining data for manicurists and clients, correlation analysis found a significant effect on the development of ACD to 2-HPMA (p=0.003) and EGDMA (p=0.005), as well as for hand dermatitis to 2-HEMA (p=0.05) and 2-HEA (p=0.044).

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Allergic contact dermatitis caused by acrylates in nail cosmetic products: Case reports and review of the literatures

Cited by 6 publications

References 14 publications

Acrylates as a significant causes of allergic contact dermatitis – new sources of exposure

Acrylates as a significant causes of allergic contact dermatitis – new sources of exposure

Unwanted Skin Reactions to Acrylates – an Update

Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients

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