Allergic contact cheilitis caused by menthol in toothpaste and throat medication: a case report

Bourgeois, Pieter; Goossens, An

doi:10.1111/cod.12571

Cited by 13 publications

(8 citation statements)

References 14 publications

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“…Patch test reaction was positive to menthol, peppermint oil and the menthol-containing throat spray. Semi patch test for his toothpaste which contained menthol was also positive [113].…”

Section: Mentholmentioning

confidence: 99%

“…The patch-test results were positive to peppermint oil and indicated that peppermint oil was the most likely cause of allergic reactions in these patients [50]. Another case report noted allergic contact cheilitis caused by menthol in a toothpaste and throat medication [51]. In the period of 2000-2009, positive patch test reactions or positive usage tests to the patients' own cosmetic products were investigated.…”

Section: Peppermint Essential Oilmentioning

confidence: 99%

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Essential Oils and Their Single Compounds in Cosmetics—A Critical Review

2018

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Essential oils are widely incorporated in cosmetic products, perfumes and related household products due to the variety of their properties but mainly due to their pleasant odour. The composition of these volatile natural complex mixtures may vary depending on the quality of plant material from which they were obtained and the extraction method by which they were derived. These factors are also important in ensuring the safe use of essential oils in personal care products. As they contain compounds with varied chemical structure and effects, skin sensitivity and irritations as well as other symptoms may arise after their application. Although essential oils are considered as safe and nontoxic when used at low concentrations, available scientific literature indicates that essential oils and their compounds may possess a strong allergy potential. This review focuses on side effects and allergy contact dermatitis caused by selected essential oils and their single compounds in cosmetic products, summarizing data from the most recent scientific literature.

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“…Patch test reaction was positive to menthol, peppermint oil and the menthol-containing throat spray. Semi patch test for his toothpaste which contained menthol was also positive [113].…”

Section: Mentholmentioning

confidence: 99%

Section: Peppermint Essential Oilmentioning

confidence: 99%

Essential Oils and Their Single Compounds in Cosmetics—A Critical Review

2018

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“…6,17,18 Toothpaste flavors, which are fragrance mixtures commonly containing oils of peppermint and spearmint, carvone and anethole, seem to represent the most common toothpaste allergens. 4,5,7,10,13,[19][20][21] Other allergens in toothpaste flavors include menthol and dipentene 5,7 and less commonly associated substances include chlorexedine, stannous fluoride, triclosan, propolis and hydrogen peroxide. 1,2,[22][23][24][25] Whitening and anti-tartar toothpastes are more associated with oral reactions due to the constant presence of irritant agents, especially peroxyde, pyrophosphate and hexametaphosphate, substances responsible for improving teeth cleanliness and whiteness.…”

Section: Discussionmentioning

confidence: 99%

Estomatite de contato a creme dental: importância do diagnóstico diferencial

Amaral

Miranda

Netto

et al. 2019

Rev. Bras. Odontol.

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Objetivo: o objetivo do presente trabalho é relatar 4 casos de estomatite de contato relacionada a cremes dentais com foco em sua apresentação clínica e a importância do diagnóstico diferencial com outras condições reativas, inflamatórias e potencialmente malignas da cavidade oral. Relato de caso: os 4 casos envolveram mulheres adultas e apresentaram-se clinicamente como manchas e placas brancas e vermelhas multifocais acometendo a língua, o assoalho de boca e a mucosa labial, associadas a discreta sensação de queimação e com evolução de 7 a 15 dias. Todas as pacientes relataram terem iniciado o uso de um novo creme dental poucos dias antes do surgimento dos sintomas e todas as lesões desapareceram em um intervalo de 5 a 7 dias após a suspensão do seu uso. Conclusão: estomatite de contato relacionada a cremes dentais deve ser considerada no diagnóstico diferencial das manchas e placas brancas e vermelhas da cavidade oral, e a história clínica detalhada é essencial para o diagnóstico final correto e precoce. Como o uso de novos enxaguatórios e cremes dentais, assim como de outros produtos de higiene oral, vem aumentando, dentistas clínicos devem estar atentos a possibilidade de reações locais orais associadas ao seu uso.

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“…gastrointestinal symptoms are reported to be associated with citric acid consumption 9 hydrated silica active in extrinsic stain and plaque removal 49 use of silica nanoparticles in-vivo poses risks of bioaccumulation 50 mica not found not found sodium bicarbonate active in extrinsic stain and plaque removal 51 rare reactions such as dizziness, confusion, irritability, memory problems, muscle pain or aches, vomiting, or weakness are reported to be associated with its excess consumption 52 titanium dioxide active in extrinsic stain removal 53 mixed findings; recent work suggested that titanium dioxide in higher concentrations may be dangerous 53 ; particularly, chronic health effects include possible harm to the upper respiratory tract and lungs 54 trisodium phosphate not found not found xylitol active in caries prevention 55 no carcinogenicity 55 Wetting agents glycerin used to prevent toothpaste from drying out 56 generally used with low toxicity, but at high concentrations, it could impair blood circulation 57 Mentha viridis (spearmint) leaf oil analgesic counterirritant sensitizer and allergenic 59 Melissa officinalis flower/leaf/ stem water antimicrobial and antioxidant agent case reports on contact dermatitis 60 Aloe barbadensis leaf juice emollient and antimicrobial agent; used to treat aphthous ulcers and to reduce the incidence of alveolar osteitis after third molar extraction surgeries 61 ; a mouthrinse containing A. vera was found to reduce gingival inflammation and gingival bleeding 62 and was more effective than Listerine ® in reducing the count of aerobic, microaerophilic and anaerobic bacteria 63 not found…”

Section: Identification Of Active Ingredientsmentioning

confidence: 99%

Green dentistry: Organic toothpaste formulations. A literature review

Mazur¹,

Ndokaj²,

Bietolini³

et al. 2022

Dent. Med. Probl.

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Dentistry as a profession should take into account the goals of sustainable development in daily practice and encourage the transition to a green economy. Consumers are becoming more conscious about the impact of self-care products, including toothpastes, on the environment. Organic toothpastes are considered very safe. A broad literature review was conducted to: (i) identify the ingredients in available organic toothpastes; (ii) classify them into active and inactive; and (iii) evaluate each ingredient's purpose and the adverse events that may be associated with its use. A comprehensive list of available organic toothpastes and their ingredients was compiled based on the products from the largest Italian organic supermarket chain (NaturaSì ® ) that is representative of the European market. Then, PubMed, Scopus and Google Scholar databases were searched to identify, classify and evaluate each ingredient. The final sample consisted of 46 organic toothpastes that included 156 ingredients; 139 (89.1%) and 17 (10.9%) were classified as active and inactive, respectively. Overall, 32 (20.5%) ingredients were associated with known adverse events. The results of this study indicate that organic toothpastes are highly biocompatible with oral cavity tissues. Careful product selection may help consumers avoid potential adverse effects that can be caused by ingredients such as polymers (e.g., polyethylene glycol) and carbomers, detergent agents (e.g., sodium lauryl sulfate), and triclosan. The lack of clinical studies should encourage the development of sufficient evidence to provide consumers with recommendations for daily use, based on both efficacy and biocompatibility.

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Allergic contact cheilitis caused by menthol in toothpaste and throat medication: a case report

Cited by 13 publications

References 14 publications

Essential Oils and Their Single Compounds in Cosmetics—A Critical Review

Essential Oils and Their Single Compounds in Cosmetics—A Critical Review

Estomatite de contato a creme dental: importância do diagnóstico diferencial

Green dentistry: Organic toothpaste formulations. A literature review

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