Alkaloids of Mappia foetida

Govindachari, T. R.; Viswanathan, N.

doi:10.1016/s0031-9422(00)89852-0

Cited by 173 publications

(72 citation statements)

References 5 publications

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“…Many authors have reported beneficial effects of sulphuric acid in breaking seed coat dormancy in a number of leguminous plants (Mohammad and Amuse, 2003) and other plants which have hard seed coat (Hosseini et al, 2013). The acid helps in removal of cuticle and softening of testa which facilitates water absorption and gaseous exchange (Govindachari and Viswanathan, 1972) however increase in acid concentration to 20% reduced the germination was recorded due to damage of embryo or killing the endosperm cells.…”

Section: Discussion: Seed Germinationmentioning

confidence: 99%

In Vitro Seed Germination and Embryo Culture in Nothapodytes foetida (Wight) Sleumer

Kaveri

Srinath

2015

ILNS

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ABSTRACT. In vitro seed germination and embryo culture have been achieved in Nothapodytes foetida, this plant is known for its rich source of anticancer drug i. e., Camptothecin. In present study both normal and decoated seeds were subjected to different treatments viz., H2O, GA 3 , H2O2, H2SO4, chlorine water and mechanical scarification, further these were germinated on water agar medium (WA), filter paper bridge (FB), half strength MS (HMS) and full strength MS (FMS) medium. The highest percentage (69%) of germination was achieved from decoated seeds treated with 10mg/L GA 3 and germinated on Filter Paper Bridge. And for embryo culture mature embryos were inoculated on MS medium containing various combination and concentrations of cytokinins (BAP, Kn and TDZ) and auxin (IAA and NAA) for rapid conversion into a plantlet. Among the different combinations of growth regulators; highest frequency (100%) of plantlet conversion was obtained on MS medium containing Kn (1.0mg/L) and NAA (0.2mg/L).

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Section: Discussion: Seed Germinationmentioning

confidence: 99%

In Vitro Seed Germination and Embryo Culture in Nothapodytes foetida (Wight) Sleumer

Kaveri

Srinath

2015

ILNS

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“…The important active principle is camptothecin, which is an anticancer compound, first isolated from Camptotheca acuminata [8]. Later it was isolated from Merrilliodendron megacarpum [9], Nothapodytes nimmoniana [10], Ervatamia heyneana, Mostuea brunonis [11] …”

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confidence: 99%

A New Record of Ophiorrhiza trichocarpon Blume (Rubiaceae: Ophiorrhizeae) from Western Ghats, India: Another Source Plant of Camptothecin

Sibi¹,

Dintu²,

Renjith³

et al. 2012

J. Sci. Res.

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“…1). CPT is a monoterpene cytotoxic quinoline alkaloid, first isolated from the plant Camptotheca acuminata [4] which belongs to the family Nyssaceae and later in N. nimmoniana [5] . It is also reported in Pyrenacantha klaineana [6] , Ophiorrhiza species [7] , Chenomorpha fragrance [8] , Dysoxylum binectariferum [9] , and other related species [10] .…”

Section: Introductionmentioning

confidence: 99%

Production of Camptothecin from Nothapodytes nimmoniana: An Overview

Pr¹,

Xavier²,

Reddy³

et al. 2017

IJLSSR

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ABSTRACT-Nothapodytes nimmoniana is an endangered tree endemic to Western Ghats, India and it is the convenient source for large scale isolation of camptothecin (CPT). Since the first report of CPT detection in N. nimmoniana, significant work has been done on its applications. Due to heavy collection of its wood chips for CPT, population is under threat in India. Several plant tissue culture techniques offer alternative strategies for clonal propagation and CPT production to conserve the species. Various strategies are employed to enhance in vitro condition response through culture medium optimization, elicitation, and artificial seed method. In this article, we have reviewed progress made so far on different methods of plant tissue culture techniques for production of camptothecin from N. nimmoniana and biosynthesis of CPT in details.

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Alkaloids of Mappia foetida

Cited by 173 publications

References 5 publications

<i>In Vitro</i> Seed Germination and Embryo Culture in <i>Nothapodytes foetida</i> (Wight) Sleumer

<i>In Vitro</i> Seed Germination and Embryo Culture in <i>Nothapodytes foetida</i> (Wight) Sleumer

A New Record of <i>Ophiorrhiza trichocarpon</i> Blume (Rubiaceae: Ophiorrhizeae) from Western Ghats, India: Another Source Plant of Camptothecin

Production of Camptothecin from Nothapodytes nimmoniana: An Overview

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