2013
DOI: 10.1016/j.ijcard.2012.01.030
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Alcohol and the heart: To abstain or not to abstain?

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Cited by 57 publications
(34 citation statements)
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References 157 publications
(17 reference statements)
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“…[3][4][5][6][7][8][9][10] In addition, most of the existing studies have not been population based and have often been conducted in specialized units which raise concerns about the generalizability of the findings. There is consequently a need for large-scale studies on unselected patients in order better to comprehend the impact of lifestyle on stroke outcomes, including stroke severity, the risk of important medical complications, and mortality in acute stroke care settings.…”
mentioning
confidence: 99%
“…[3][4][5][6][7][8][9][10] In addition, most of the existing studies have not been population based and have often been conducted in specialized units which raise concerns about the generalizability of the findings. There is consequently a need for large-scale studies on unselected patients in order better to comprehend the impact of lifestyle on stroke outcomes, including stroke severity, the risk of important medical complications, and mortality in acute stroke care settings.…”
mentioning
confidence: 99%
“…In a meta-analysis, the intake of one drink a day was consistently associated with a 14%–25% reduction in the risk of these outcomes compared with abstention 1. A recent review concluded that existing data clearly demonstrate many favourable biological effects of light to moderate alcohol consumption on the cardiovascular system 2. However, a small number of studies have failed to demonstrate such benefit, and heavier alcohol consumption is associated with cardiovascular complications 2.…”
Section: Introductionmentioning
confidence: 99%
“…Zudem gibt es in zahlreichen Untersuchungen Hinweise auf weitere positive Eigenschaften von Alkohol, z. B. auf das Lipidprofil mit LDL-Reduktion und HDL-Erhöhung, auf die Gerinnungs-und Fibrinolysekaskade, die Plätt-chenaggregation, den oxidativen Stress, die Insulinsensitivität und die Endothelfunktion sowie antiinflammatorische Effekte, die zu einer Risikoreduktion kardiovaskulärer Ereignisse führen könnten [46,62,64,67]. Des Weiteren gibt es experimentelle Daten, die einen direkten Effekt von Alkohol auf Kardiomyozyten vermuten lassen, die zu einer protektiven Wirkung bezüglich ischämie-bzw.…”
Section: Fazit Alkoholunclassified