Alcohol and plasma triglycerides

Klop, Boudewijn; Rego, Ana Torres do; Cabezas, Manuel Castro

doi:10.1097/mol.0b013e3283606845

Cited by 135 publications

(93 citation statements)

References 37 publications

(45 reference statements)

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“…In alcoholic pancreatitis, alcohol can directly affect the metabolism of TG, causing elevated TG levels, and is therefore directly involved in the occurrence of pancreatitis. Thus, an elevated TG level can be seen as an associated etiological factor of alcoholic pancreatitis [16], whereas it may be considered as concurrent symptom of biliary pancreatitis [17]. In addition, the relationships between TG elevation and the severity and prognosis of AP, as reported in the literature, are also inconsistent.…”

Section: Discussionmentioning

confidence: 99%

Clinical significance of serum triglyceride elevation at early stage of acute biliary pancreatitis

Cheng

Luo

et al. 2015

BMC Gastroenterol

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BackgroundPancreatitis induced by hypertriglyceridemia (HTG) has gained much attention. However, very limited numbers of studies have focused on the clinical significance of TG elevation in non-HTG induced pancreatitis, such as acute biliary pancreatitis (ABP). This study aimed to study the clinical significances of triglyceride (TG) elevation in patients with ABP.MethodsWe retrospectively analyzed a total of 426 ABP cases in our research center. According to the highest TG level within 72 h of disease onset, the patients were divided into a normal TG group and an elevated TG group. We analyzed the differences between the two groups of patients in aspects such as general information, disease severity, APACHE II (acute physiology and chronic health evaluation II) and Ranson scores, inflammatory cytokines, complications and prognosis.ResultsCompared with the normal TG group, patients in the elevated TG group showed a significantly higher body mass index and were significantly younger. TG elevation at the early stage of ABP was associated with higher risk of severe pancreatitis and organ failures, especially respiratory failure. For patients with severe pancreatitis, those with elevated TG levels were more likely to have a larger area of necrosis, and higher incidence of pancreatic abscess as well as higher mortality (17.78% versus 9.80%, P < 0.05).ConclusionsIn ABP patients, TG elevation might participate in the aggravation of pancreatitis and the occurrence of systemic or local complications. Thus, the TG level may serve as an important indicator to determine the prognosis of patients with ABP.

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Section: Discussionmentioning

confidence: 99%

Clinical significance of serum triglyceride elevation at early stage of acute biliary pancreatitis

Cheng

Luo

et al. 2015

BMC Gastroenterol

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“…The mean fasting glucose of our subjects-99.70 mg/dL-was almost equal to the cutoff value for impaired fasting glucose (≥100 mg/dL), as described by the International Diabetes Federation (IDF), whereas the mean level of triglycerides-187.14 mg/dL-was higher than the cutoff value considered by the NCEP-ATP III as a risk factor for MS (≥150 mg/dL). Furthermore, it is known that high alcohol intake is associated with elevated levels of serum triglycerides, cardiovascular disease, fatty liver disease, and acute pancreatitis of alcoholic etiology (Klop, Rego, & Cabezas, 2013); alcohol intake per se was not addressed in this study. In the present study, 72.64% of subjects were overweight/obese.…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Metabolic Syndrome Among Soldiers of the Military Police of Bahia State, Brazil

Filho

Júnior

2013

Am J Mens Health

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ArticleThe life expectancy of men is nearly 8 years less than that of women, and social factors are known to contribute to the morbidity and mortality rates of men. Men in almost all age groups have higher mortality rates from non-sexspecific diseases than women (Chagas, Zilli, Ferreira, Moretti, & Ramos, 2009). The differences in the rates of morbidity and mortality between men and women may well be explained by genetic and hormonal factors, lifestyle, and habits (alcohol, smoking, working conditions), but they could also be a consequence of the way in which men are raised and the way in which gender roles are assigned in different societies. Therefore, in the process of acquiring a masculine role, men adopt behaviors that subjectively, but ostensibly, renounce that they are childish, homosexual, or feminine. In an effort to renounce these features, behaviors that are associated with sensitivity and tenderness are suppressed. This includes the denial of pain. Men would reduce their self-preservation in an effort to affirm the role of a strong provider and leader (Braz, 2005). The prevalence of cardiovascular diseases has been one of the key concerns for health professionals and organizations worldwide. Some of the World Health Organization (WHO) projections forecast a 250% increase in morbidity and mortality events due to cardiovascular diseases in the Brazilian population. Intervention programs that could reduce cardiovascular risk factors among Brazilians are thus urgently needed (Chagas et al., 2009 AbstractThe mortality rate of men is generally higher than that of women, irrespective of the age group. Currently, a key concern for health care professionals is the prevalence of risk factors associated with cardiovascular disease and metabolic syndrome. This study aimed at assessing the prevalence of individual risk factors for cardiovascular disease as well as the prevalence of metabolic syndrome among men serving in the Military Police Corps of the state of Bahia, Brazil. This service employs mostly men, and they are known to experience high levels of occupational stress and professional victimization. We conducted a cross-sectional study among military police soldiers (n = 452) who were candidates for a military police training course in Bahia, Brazil. All candidates who attended the selection process were evaluated according to the criteria of the National Cholesterol Education Program's Adult Panel III in order to assess the presence of medical disorders that could contribute to cardiovascular disease and metabolic syndrome. The authors identified a high prevalence of hypertension (55.76%), hypertriglyceridemia (50.85%), waist circumference of >102 cm (31.76%), low high-density lipoprotein cholesterol levels (30.46%), and impaired fasting glucose (28.15%) in our subjects. The overall prevalence of metabolic syndrome was 38.54%. The authors suggest that measures should be taken to ensure that military policemen receive continued medical care, both in their professional capacity and in their personal circu...

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“…Light-to-moderate alcohol intake has been associated with lower insulin levels and improved glycaemic control [3], lower levels of fibrinogen [4], and reduced inflammation [5] whereas the antioxidant polyphenolics in red wine have been linked to reduced arterial stiffness [6]. In contrast, heavier alcohol intake, irrespective of beverage type, has been linked to increased blood pressure (BP) [7], triglycerides [8], homocysteine levels [9], arterial stiffness [10], and incidence of the metabolic syndrome [11]. Such contrasting influences may explain, at least in part, why there is a U-shaped relationship between alcohol consumption and incidence of coronary artery disease (CAD) [12], a pattern also seen in type 2 diabetes [13].…”

Section: Introductionmentioning

confidence: 99%

The effects of alcohol on ambulatory blood pressure and other cardiovascular risk factors in type 2 diabetes

Mori

Burke

Zilkens

et al. 2016

Journal of Hypertension

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Alcohol and plasma triglycerides

Cited by 135 publications

References 37 publications

Clinical significance of serum triglyceride elevation at early stage of acute biliary pancreatitis

Clinical significance of serum triglyceride elevation at early stage of acute biliary pancreatitis

The Prevalence of Metabolic Syndrome Among Soldiers of the Military Police of Bahia State, Brazil

The effects of alcohol on ambulatory blood pressure and other cardiovascular risk factors in type 2 diabetes

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