Albumin metabolism in hookworm anaemias

Anemia survey in Trinidad and Tobago.

“…Hookworm infestation present in 11 per cent of the subjects may lead to fecal loss of protein as has been demonstrated by Gillis, et al (1964) 20 and by Blackman, et al (1965). 21 Normal serum protein values in the majority of the subjects, even in the presence of hookworm infection, suggest the fact that protein deprivation did not contribute significantly to the causation of anemia in the population studied.…”

“…21 Normal serum protein values in the majority of the subjects, even in the presence of hookworm infection, suggest the fact that protein deprivation did not contribute significantly to the causation of anemia in the population studied.…”

Hookworm Disease: Host-Pathogen Biology

“…Blackman et aI., using 131 I-labeled albumin, have demonstrated that fecal protein loss correlates with hookworm load. They concluded that there is a daily loss of 0.1 g of albumin per 100 N. americanus hookworms [19].…”

Hookworm Disease: Nutritional Implications

“…While the worms feed in the intestine, variable amounts of plasma and extracellular fluid along with erythrocytes may be lost into the intestinal lumen [11,12]. Loss of protein into the intestine has been studied by the measurement of fecal nitrogen excretion [31,32] and by the use of proteins labelled with 131 1 [30,33] and slCr [23,34,35]. While the fecal nitrogen excretion was not markedly different between patients with mild infection «200 worms) and those with no infection [31], fecal nitrogen excretion was increased in patients with heavy infection [32].…”

“…While the fecal nitrogen excretion was not markedly different between patients with mild infection «200 worms) and those with no infection [31], fecal nitrogen excretion was increased in patients with heavy infection [32]. Studies by Gilles et al [30] and Blackman et al [33] with 131 1_ labeled albumin revealed that the intestinal protein loss was increased with heavy hookworm infection. However, there are methodologic problems in studies with radioiodinated proteins [36].…”