Aktivitas Antibakteri Ekstrak Etanol Daun Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr.) terhadap Staphylococcus aureus dan Salmonella typhi.

Rachmatiah, Tiah; Syafriana, Vilya; Helma, Fitria

doi:10.33221/jikes.v19i03.598

Cited by 5 publications

(10 citation statements)

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“…The difference results between E. coli and S. typhi against the akar kaik-kaik leaves extract probably due to the presence of flavonoid in extract. Our results showed no flavonoid content, while Rachmatiah et al [38] showed positive in flavonoid test. Flavonoid could interrupt the bacterial cell wall and membrane of microorganisms.…”

Section: Antimicrobial Activitycontrasting

confidence: 59%

“…Flavonoids were more dissolved in 96% ethanol rather than at 70% ethanol [36,37]. This assumption was also supported by the result of Rachmatiah et al [38], which showed a positive result in flavonoid screening in 96% ethanol extract of akar kaik-kaik leaves.…”

Section: Phytochemicals Screeningmentioning

confidence: 73%

“…The research about the antimicrobial activity from akar kaik-kaik leaves was very limited. The only study regarding antimicrobial activity was reported by Rachmatiah et al [38] which using 96% ethanol as a solvent. They reported that 96% ethanol extract of akar kaik-kaik leaves have activities against S. aureus and Salmonella typhi.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

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Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans

Syafriana¹,

Setyaningsih²,

Rachmawani³

et al. 2021

Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)

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Akar kaik-kaik (Uncaria cordata) or known as hook vine is one of the medicinal plants whose leaves are used in traditional medicine as an antidiabetic by the people of Riau. Other than that, this plant also has potential as an antimicrobial agent due to the dominant of alkaloid content possessed by members of the genus Uncaria. This research aims to study the antimicrobial activity from the ethanol extract of akar kaik-kaik leaves against Staphylococcus aureus (Gram-positive bacteria), Escherichia coli (Gram-negative bacteria), and Candida albicans (yeast). The extraction was carried out using the maceration method and a solvent of 70% ethanol. The extract then tested for phytochemical screening to find out the secondary metabolite. After that, the extract was tested for antimicrobial activity. The test was done by Kirby-Bauer Method at Nutrient Agar (NA) for bacteria, and Sabouraud Dextrose Agar (SDA) for yeast. The extract contained alkaloid, saponin, and tannin according to the phytochemical analysis. The antimicrobial activity showed that the extract can inhibit the growth of S. aureus at a concentration of 10%, 20%, and 40% respectively about 6.91 ± 0.04 mm, 8.51 ± 0.14 mm, and 10.89 ± 1.09 mm. Meanwhile, the extract cannot inhibit the growth of E. coli and C. albicans.

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Section: Antimicrobial Activitycontrasting

confidence: 59%

Section: Phytochemicals Screeningmentioning

confidence: 73%

Section: Antimicrobial Activitymentioning

confidence: 99%

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Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans

Syafriana¹,

Setyaningsih²,

Rachmawani³

et al. 2021

Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)

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“…Tumbuhan kaik-kaik yang berasal dari hutan larangan adat Kabupaten Kampar, Riau mempunyai beberapa aktivitas diantaranya ekstrak etanol daun mempunyai aktivitas sebagai antibakteri terhadap bakteri Staphylococcus aureus dan Salmonella typhi [13] , ekstrak etanol daun ini juga mempunyai aktivitas terhadap bakteri Staphylococcus aureus, Escherichia coli dan Candida albicans [14] . Ekstrak etanol dari akarnya mempunyai aktivitas yang dapat menurunkan kolesterol pada mencit jantan putih dengan dosis terbaik pada 200 mg/kgBW [15] .…”

Section: Pendahuluanunclassified

“…Skrining fitokimia yang dilakukan meliputi pemeriksaan alkaloid, flavonoid, fenolik, saponin, steroid dan terpenoid [13], [18], [20] .…”

Section: Skrining Fitokimiaunclassified

Aktivitas Anti Hiperurisemia Ekstrak Akar Kaik-kaik (Uncaria cordata. L. Merr) pada Mencit (Mus muscullus) yang Diinduksi Kalium Oksonat

et al. 2022

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Consuming food containing high level of purin leads to increase uric acid in the blood which, in turn, cause hyperuricemia or high uric acid level. The use of improper allopurinol for hyperuricemia medication that doesn’t follow medical doctor’s prescription can give harmful side effect. It is therefore required to use an alternative safe medication. Uncaria cordata (Lour.) Merr.) is a plant often used for medication of high levels of blood uric acid by communities in Pasar Ngalam village, Bengkulu Province. This research aims to evaluate the potency of extracted compounds from Uncaria cordata (Lour.) Merr.) in reducing uric acid of Mus musculus suffering from hyperuricemia. This research is a laboratory experiment using completed random design. As many as 25 Mus musculus were divided into 5 groups of treatment: PN = normal treatment, PA = treated with allopurinol, P1 – P3 = treated with extracted compound of Uncaria cordata (Lour.) Merr.) with a dose of 5.3 mg/30gBW (P1); 10.6 mg/30gBW (P2); and 21.2 mg/30gBW (P3). In order for Mus musculus to suffer from high uric acid level, potassium oxonate-induced hyperuricemia was injected. The result showed that extracted compounds of Uncaria cordata (Lour.) Merr.) using ethanol exhibited antihyperuricemia proven by decline of uric acid level of Mus musculus from hyperuricemia on each given dose. Decreasing uric acid level for each given dose of ethanol extract (5.3 mg/30gBW, 10.6mg/30gBW and 21.2mg/30gBW) was not significant different (0.541; with a ³0.05).

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Aktivitas antioksidan dan kandungan flavonoid total ekstrak etanol batang bajakah kalalawit (Uncaria cordata (Lour) Merr.) asal Kecamatan Loksado Kalimantan Selatan

Wathan,

Safarina,

Fitriana

2024

SJP

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Bajakah kalalawit (Uncaria cordata (Lour) Merr.) is widely used by Dayak Tribes, based on empirical evidence, and often used to treat diabetes and various diseases such as cancer. This research aimed to determine the total flavonoid content and antioxidant activity of the ethanolic extract of U. cordata stems. The sample used bajakah kalalawit from Loklahung village, Loksado District, South Hulu Sungai Regency, South Kalimantan Province. Flavonoid levels were determined using quercetin standards, 10% AlCl3 reagent, and 5% acetic acid, then measured at a wavelength of 416 nm, while the antioxidant activity using DPPH 0.4 mM in UV-Vis spectroscopy at a wavelength of 516 nm. The results obtained were a thick extract mass with a dark brown color and a distinctive aroma. The total flavonoid content of the ethanol extract of U. cordata stems was found to be 3.6 ± 0.086 % w/w equivalent quercetin and showed very strong antioxidant activity with an IC50 value of 9.159 ppm.

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Aktivitas Antibakteri Ekstrak Etanol Daun Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr.) terhadap Staphylococcus aureus dan Salmonella typhi.

Cited by 5 publications

References 0 publications

Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans

Antimicrobial Activity of Ethanol Extract of Akar Kaik-kaik (Uncaria cordata (Lour.) Merr.) Leaves Against Staphylococcus aureus, Escherichia coli, and Candida albicans

Aktivitas Anti Hiperurisemia Ekstrak Akar Kaik-kaik (Uncaria cordata. L. Merr) pada Mencit (Mus muscullus) yang Diinduksi Kalium Oksonat

Aktivitas antioksidan dan kandungan flavonoid total ekstrak etanol batang bajakah kalalawit (Uncaria cordata (Lour) Merr.) asal Kecamatan Loksado Kalimantan Selatan

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