AKTIVITAS ANTIBAKTERI BIJI,KULIT DAN DAUN PEPAYA (Carica papaya L.) TERHADAP BAKTERI Escherichia Coli dan Staphylococcus Aureus

Roni, Asep; Maesaroh, Maesaroh; Marliani, Lia

doi:10.26874/kjif.v6i1.134

Cited by 12 publications

(17 citation statements)

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“…The highest effect was at a concentration of 75%, and the inhibition zone was 6.73 mm. Research by (Roni, Maesaroh, and Marliani, 2019) 22 reported that ethanol fraction of papaya seed has antibacterial effects against S. aureus with an inhibition zone diameter of 12.2 mm. (Kusumawati's 2020) 21 also found that the ethanol fraction of papaya seeds has an antibacterial effect against S. aureus with inhibition zone diameter of 5 to 9 mm.…”

Section: Antibacterial Analysismentioning

confidence: 99%

Green synthesis of silver nanoparticles from papaya seed extracts with alkaloid content for antibacterial application

Surura

Abdullah²,

Ginting³

et al. 2021

J. Teknol. Laboratorium

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This research aims to develop a silver nanoparticle (AgNPs) using several plant extracts for antibacterial application. The papaya seed extract has been fractioned by n-hexane, ethyl acetate, water, and ethanol. The n-hexane fraction was the only fraction that succeeded in synthesizing AgNPs. The characterization methods showed AgNPs marked at 430 nm with UV-Vis and 1640 cm-1 with FTIR. SEM observed the aggregation of spherical AgNPs at the 200 nm scale. The particle size of 91.3 nm was measured with PSA that confirmed the nanoscale of the synthesized material. All fractions contained alkaloid compound, and ethyl acetate fraction showed a group of indole with specific wavenumber at 2623 cm-1, 1737 cm-1, and 1237 cm-1 representing N-H, C=O, C-N, respectively. All fractions at every concentration (25%, 50%, 75%, 100%) have been tested and showed the medium effect on bacterial growth inhibition. Among all fractions, the AgNPs n-hexane fraction has the highest bacterial effect, which was indicated by mean values of inhibition zone 7.2 mm against S.aureus, as well as 6.6 mm against E.coli. ANOVA analysis showed that AgNPs n-hexane fraction has a significant inhibition zone compared to other fractions against S.aureus (p=0.002), but not significant to E.coli (p=0.128). The insignificant results on E.coli because of gram-negative bacteria's biophysical characteristics, such as membrane cell wall and flagellin. This research emphasized that AgNPs could be synthesized via a green process of nucleation by using plant extract that effectively inhibits the growth of S.aureus and E.coli. Further studies on the mechanism of the antibacterial effect at the molecular level might be investigated soon.

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Section: Antibacterial Analysismentioning

confidence: 99%

Green synthesis of silver nanoparticles from papaya seed extracts with alkaloid content for antibacterial application

Surura

Abdullah²,

Ginting³

et al. 2021

J. Teknol. Laboratorium

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“…Senyawa flavonoid merupakan salah satu antibakteri maupun antifungi karena memiliki kemampuan membentuk senyawa kompleks yang berikatan pada protein ekstraseluler yang bersifat larut serta berikatan dengan dinding sel mikroorganisme. Hal ini dikarenakan, salah satu senyawa flavonoid bersifat lipofilik dan bekerja sebagai agen penghambat Topoisomerase tipe II sehingga dapat menyebabkan proses replikasi maupun transkripsi sel mikroba menjadi terhambat Roni et al (2019), Penelitian yang telah dilakukan oleh Hartini and Mursyda (2019) menunjukkan hasil diameter zona hambat yang lebih besar dibandingkan dengan beberapa penelitian sebelumnya Tuntun (2016), dikarenakan pada penelitian tersebut menggunakan daun pepaya yang lebih muda. Menurut Gogna et al (2015) bahwa daun pepaya muda lebih tinggi kandungan flavonoid sehingga mempengaruhi terbentuknya zona hambat selain kecepatan difusi maupun stabilitas bahan kimianya.…”

Section: Hasil Dan Pembahasanunclassified

The Activities Of Combination Citrus hystrix Peel Extract and Carica papaya Leaves Extract Against Candida albicans and Escherichia coli

Anitasari

Sari

2021

medicra

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Citrus hystrix Peel Extract and Carica papaya Leaves Extract contain several active components that can be used as antimicrobial compounds. The aim was to test a mixture of extracts from Citrus hystrix peel and Carica papaya leaves as growth inhibiting compounds for Candida albicans and Escherichia coli. This study used 4 levels of treatment, namely a combination of papaya leaves extract and orange fruit peel at concentrations of 0%, 25%, 50%, 75% and 100%. The research data were in the form of the diameter of the growth inhibition of Escherichia coli and Candida fungi, which were analyzed using the Kruskall-Wallis test at 5% confidence level and 5% Duncan's test. showed a significant difference between treatments, but the concentration of 100% showed better results to inhibit Escherichia coli (1.58 ± 0.28 d) and the growth of Candida albicans (1.53 ± 0.57b) compared to controls and other concentrations.

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“…Hasil penelitian daun pepaya dan buah pepaya ini berbeda dengan penelitian sebelumnya yang menyatakan daun dan buah pepaya mempunyai sifat antibakteri yang dapat menghambat pertumbuhan beberapa jenis bakteri. 13 Perbedaan hasil penelitian ini kemungkinan dipengaruhi karena tidak terdapat standarisasi dalam pembuatan ekstrak, sehingga apabila penelitian dilakukan di berbagai laboratorium yang berbeda-beda dengan metode ekstraksi yang berbeda-beda, maka hasil penelitian yang didapat akan berbeda pula, beberapa faktor lainnya yang juga dapat mempengaruhi mutu ekstrak adalah jumlah dan jenis senyawa kimia, metode ekstraksi, dan penggunaan jenis pelarut dalam mengekstrak. 14…”

Section: Diskusiunclassified

Efek Antibakteri Tumbuhan Pepaya (Carica Papaya L.) Terhadap Porpyromonas Gingivalis (Laporan Penelitian)

Amin

Ariwibowo

Febria³

2021

JKGT

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Background: Porphyromonas gingivalis is one of the bacteria that cause pulp necrosis, NaOCl is an irrigation solution that has become the gold standard in endodontic treatment, however NaOCl is toxic, so other alternative materials are needed. One usable material is papaya plant (Carica papaya L.) which has antibacterial properties. Objective: to know the differences in the activity of papaya leaves extract, papaya seed extract, and papaya fruit juice in inhibiting P.gingivalis. Methods: This study is an in vitro experimental laboratory of agar well diffusion method used papaya seeds extract, papaya leaves extract and papaya fruit juice in several consentrations (6.25%,12.5%,25%,50%, and 100%) and NaOCl 5,25% as positive control. Results: This study showed that the diameter of inhibitory zone against P.gingivalis was found on 2 concentrations of papaya seed extract, a concentration of 100% with an average 23,43 mm and concentration of 50% with an avarege 16,43 mm. The inhibition zone test of papaya leaves extract and papaya fruit juice against P.gingivalis was not found around the well. Conclusion: Papaya seed extract was able to inhibit P.gingivalis in certain concentration, while papaya leave extract and papaya fruit juice were not able to inhibit the growth of P.gingivalis.

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AKTIVITAS ANTIBAKTERI BIJI,KULIT DAN DAUN PEPAYA (Carica papaya L.) TERHADAP BAKTERI Escherichia Coli dan Staphylococcus Aureus

Cited by 12 publications

References 0 publications

Green synthesis of silver nanoparticles from papaya seed extracts with alkaloid content for antibacterial application

Green synthesis of silver nanoparticles from papaya seed extracts with alkaloid content for antibacterial application

The Activities Of Combination Citrus hystrix Peel Extract and Carica papaya Leaves Extract Against Candida albicans and Escherichia coli

Efek Antibakteri Tumbuhan Pepaya (Carica Papaya L.) Terhadap Porpyromonas Gingivalis (Laporan Penelitian)

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