AH26 releases formaldehyde

Spångberg, Larz S.W.; Barbosa, Sergio; Lavigne, Gary

doi:10.1016/s0099-2399(06)80272-4

Cited by 107 publications

(71 citation statements)

References 13 publications

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“…AH Plus maintains the advantageous properties of the precursor product AH 26 such as high radiopacity, low solubility, and little shrinkage. As the toxicity of AH 26 can be, to some extent, related to the release of a small amount of formaldehyde during chemical setting process 14,15) , AH Plus was subsequently introduced in the market to overcome the drawbacks of AH 26 such as the tendency to discoloration and the release of formaldehyde. According to the manufacturer, AH Plus has superior clinical properties than AH 26 and the formulation does not release formaldehyde.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxicity of a novel mineral trioxide aggregated-based root canal sealer

Kim

Shin

2014

Dent. Mater. J.

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The objective of this study was to assess the cytotoxicity of EndoSeal, a novel mineral trioxide aggregate-based root canal sealer in comparison with two commonly used sealers, AH Plus and Sealapex. For cytotoxicity assay, MG-63 cells and human gingival fibroblasts were incubated in culture medium containing eluates of each sealer at 1, 3, and 7 days. Cell metabolism was evaluated by the WST-1 assay. For cell adhesion assay, disc specimens were fabricated from EndoSeal and AH Plus. MG-63 cells and human gingival fibroblasts were seeded on the discs, and after 1 day and 7 days of incubation, cell morphology and cell adhesion were examined by SEM. The order of cytotoxicity of root canal sealers was as follows: EndoSeal < AH Plus < Sealapex. Both types of cells seeded on the EndoSeal specimens were much larger, flat with rough margins compared to those on the AH Plus specimens. These results suggest that EndoSeal has a satisfactory cytocompatibility.

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Section: Discussionmentioning

confidence: 99%

Cytotoxicity of a novel mineral trioxide aggregated-based root canal sealer

Kim

Shin

2014

Dent. Mater. J.

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“…E. faecalis is also a common single isolate from the canals of the refractory cases 9) . When tested against E. faecalis, with the release of formaldehyde as an antimicrobial agent 7,11) , AH26 has significantly stronger bacterialcidal effect than Roth 801, MCS, Dentalis, Apexit, Ketac Endo, AH Plus, and RSA. The sealers, Dentalis, Apexit, AH Plus and RSA, do not provide any antimicrobial effect against E. faecalis.…”

Section: ⅳ Discussionmentioning

confidence: 99%

Antimicrobial activity of eight root canal sealers before and after setting

Fang

Lee

Lai

2002

J Korean Acad Conserv Dent

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“…52 Formaldehyde is released from some epoxy-based sealers (maximum rate after 48 hours), even though this amount is less than that of paraformaldehyde. 53 The leakage of formaldehyde from the epoxy sealers has been contributed to the mutagenic effects. 48,54 Formaldehyde is carcinogenic in animals; however, there are only few evidences for showing carcinogenicity in human.…”

Section: Genotoxicity Of Root Canal Sealersmentioning

confidence: 99%