, which was introduced in 1999. It became widely adopted as the gold standard for intraocular lens selection at the time of cataract surgery. 1 It is based on partial coherence interferometry (PCI). Good precision of the device has been reported, but the failure rate for axial length measurement is approximately 17.5% to 37.84%. 1-5 Optical low coherence reflectometry and optical low coherence interfer-ABSTRACT PURPOSE: To compare axial length measurements (and failure rate) of three swept-source optical coherence tomography (SS-OCT)-based biometers: IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany), OA-2000 (Tomey, Nagoya, Japan), and Argos (Movu Inc., Komaki, Japan) to those provided by a partial coherence interferometry (PCI)-based optical biometer (IOLMaster v5.4 [Carl Zeiss Meditec]). METHODS: A total of 119 patients (171 eyes) undergoing cataract surgery were enrolled. Axial length was measured with the four biometers in a random order. Chi-square analysis was used to determine whether statistically significant differences in success rates were found between biometers. Within-subject standard deviation (S w), test-retest repeatability (TRT), coefficient of variation (CoV), and intraclass correlation coefficients (ICCs) were calculated to analyze the intraobserver repeatability. Bland-Altman plots were used for agreement assessment. RESULTS: Axial length measurements were successfully measured in 166 eyes (97.08%) with the IOLMaster 700, 166 eyes (97.08%) with the OA-2000, 170 eyes (99.42%) with the Argos, and 138 eyes (80.70%) with the IOLMaster v5.4. Chisquare analysis indicated a significant difference in the failure rate between PCI-and SS-OCT-based biometers (P < .001). Intraobserver repeatability for the IOLMaster 700, OA-2000, and Argos showed excellent repeatability with low TRT (0.03, 0.06, and 0.05 mm, respectively), low CoV (0.04%, 0.10%, 0.07%, respectively), and high ICC (1.000, 0.999, and 1.000, respectively). The Bland-Altman 95% limits of agreement were as narrow as 0.09 mm, indicating excellent agreement among the three SS-OCT biometers and the PCI biometer. CONCLUSIONS: The three SS-OCT biometers showed a significantly higher success rate for axial length measurement than the IOLMaster v5.4 in various lens opacities. These SS-OCT biometers are likely to become the gold standard for axial measurement.